2023
Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue
Kim S, Cho Y, Shin Y, Yu H, Chowdhury T, Kim S, Yi K, Choi C, Cha S, Park C, Ku J. Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue. Scientific Data 2023, 10: 448. PMID: 37438387, PMCID: PMC10338444, DOI: 10.1038/s41597-023-02365-y.Peer-Reviewed Original ResearchConceptsCell linesPatient-derived glioblastoma cell linesPatient-derived cell linesWhole exome sequencing datasetsExome sequencing datasetsGBM cell linesGlioblastoma cell linesSequence dataGenomic featuresLethal intracranial tumorSequencing technologiesSequencing datasetsMolecular markersWES datasetsGenome profilesMutational signaturesDruggable targetsNumber alterationsBiological credibilityGenomic profilesBiological platformMolecular characteristicsOriginal tissueTumor tissueGlioblastoma
2007
EVOLUTION OF HOST SPECIFICITY DRIVES REPRODUCTIVE ISOLATION AMONG RNA VIRUSES
Duffy S, Burch CL, Turner PE. EVOLUTION OF HOST SPECIFICITY DRIVES REPRODUCTIVE ISOLATION AMONG RNA VIRUSES. Evolution 2007, 61: 2614-2622. PMID: 17908251, PMCID: PMC7202233, DOI: 10.1111/j.1558-5646.2007.00226.x.Peer-Reviewed Original ResearchConceptsReproductive isolationEcological speciation hypothesisDivergent natural selectionRNA virusesAssortative mating evolvesNatural selectionHost rangeRNA bacteriophage phi6Speciation hypothesisSingle nucleotide changePhytophagous insectsEcological adaptationNovel hostEvolutionary fateWhole-genome sequencingGenetic exchangeImportant traitsBiological credibilityAlternative hostsExperimental populationsLaboratory populationsAssortative matingDirect selectionGenome sequencingNucleotide changes
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