2025
Role of non-human primate models in accelerating research and developing countermeasures against Zika virus infection
Li A, Coffey L, Mohr E, Raper J, Chahroudi A, Ausderau K, Aliota M, Friedrich T, Mitzey A, Koenig M, Golos T, Jaeger H, Roberts V, Lo J, Smith J, Hirsch A, Streblow D, Newman C, O’Connor D, Lackritz E, Van Rompay K, Waldorf K, Workgroup Z, Waldorf K, Barrett A, Beasley D, Bennie J, Bourne N, Brault A, Cehovin A, Coelho C, Diamond M, Emperador D, Faria N, Fay P, Golding J, Harris E, Hasanin N, Jaenisch T, Ko A, Lackritz E, Leighton T, Leo Y, Mehr A, Memish Z, Méndez-Rico J, Moore K, Mura M, Ng L, Osterholm M, Ostrowsky J, Peeling R, Rabe I, Salje H, Staples J, Thomas S, Ulrich A, Vanhomwegen J, Wongsawat J. Role of non-human primate models in accelerating research and developing countermeasures against Zika virus infection. The Lancet Microbe 2025, 6: 101030. PMID: 40024258, PMCID: PMC12145256, DOI: 10.1016/j.lanmic.2024.101030.Peer-Reviewed Original ResearchNon-human primate modelZika virus infectionZika virus researchPrimate modelVirus infectionCases of congenital microcephalyFetal brain injuryLaboratory-confirmed casesGestational ageZika virus strainsBrain injuryPerinatal complicationsZika virus epidemicTesting medical countermeasuresCongenital microcephalyGlobal health concernVirus researchDevelopmental abnormalitiesZika virusVirus strainsMedical countermeasuresCongenital brain injuryInfectionZikaVirus epidemic
2024
Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury
Achanta S, Gentile M, Albert C, Schulte K, Pantazides B, Crow B, Quiñones-González J, Perez J, Ford D, Patel R, Blake T, Gunn M, Jordt S. Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2024, 326: l482-l495. PMID: 38318664, PMCID: PMC11281795, DOI: 10.1152/ajplung.00162.2023.Peer-Reviewed Original ResearchAcute lung injuryBronchoalveolar lavage fluidChlorine gasChlorinated fatty acidsDecreased dynamic lung complianceHuman acute lung injuryPeak inspiratory pressureIncreased airway resistanceMedical countermeasuresControlled mechanical ventilationForensic biomarkersDynamic lung complianceFormation of microthrombiProtein adductsAir-exposed groupNeutrophilic alveolitisTesting medical countermeasuresVascular leakageNeutrophil countPulmonary edemaHistopathological featuresPotential medical countermeasuresForensic analysisInspiratory pressureLung injury
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply