2018
Combining acetabular and femoral morphology improves our understanding of the down syndrome hip
Bakouny Z, Assi A, Yared F, Khalil N, Mansour E, Yaacoub J, Skalli W, Ghanem I. Combining acetabular and femoral morphology improves our understanding of the down syndrome hip. Clinical Biomechanics 2018, 58: 96-102. PMID: 30064043, DOI: 10.1016/j.clinbiomech.2018.07.016.Peer-Reviewed Original ResearchConceptsAcetabular sector angleDown's syndrome subjectsDown syndrome compared to controlsSyndrome subjectsThree-dimensional anatomyDown syndromeAnterior acetabular sector angleHip instabilityPosterior acetabular sector angleStanding positionAsymptomatic controlsHip alterationsControl subjectsTreatment strategiesHeterogeneous anatomySyndromeFull-body biplanar X-raysPatientsAnatomyHipLower limbsAcetabular anatomySubjects
2012
Glycine treatment of the risk syndrome for psychosis: Report of two pilot studies
Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: Report of two pilot studies. European Neuropsychopharmacology 2012, 23: 931-940. PMID: 23089076, PMCID: PMC4028140, DOI: 10.1016/j.euroneuro.2012.09.008.Peer-Reviewed Original ResearchConceptsPilot studyRisk syndromeSyndrome patientsNegative symptomsShort-term pilot studyEffect sizeAdjunctive antipsychotic medicationOpen-label studyPatients meeting criteriaNMDA receptor functionDurability of effectPsychosis risk symptomsGlycine site agonistsGroup effect sizesWeeks of evaluationAntipsychotic medicationSyndrome subjectsPromising effect sizesTreatment needsLarge effect sizesMeeting criteriaCognitive impairmentReduced symptomsReceptor functionSymptoms
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