Sox17 drives functional engraftment of endothelium converted from non-vascular cells
Schachterle W, Badwe C, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura J, Rafii S. Sox17 drives functional engraftment of endothelium converted from non-vascular cells. Nature Communications 2017, 8: 13963. PMID: 28091527, PMCID: PMC5260855, DOI: 10.1038/ncomms13963.Peer-Reviewed Original ResearchConceptsEndothelial cellsMorphogenesis genesETS transcription factorsVascular endothelial cellsTreat vasculopathyAmniotic cellsGenomic targetsConsensus sitesTransplantation strategiesInjured vesselsParacrine factorsTranscription factorsNon-vascular cellsSOX17 expressionVascular functionFunctional engraftmentTransplantation studiesGene expressionPromote tissue regenerationSOX17Support metabolismEnforced expressionEC-like cellsEC gene expressionTransplantation
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