2024
Protective Factors Predict Resilient Outcomes in Clinical High-Risk Youth with the Highest Individualized Psychosis Risk Scores
Cadenhead K, Addington J, Bearden C, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S. Protective Factors Predict Resilient Outcomes in Clinical High-Risk Youth with the Highest Individualized Psychosis Risk Scores. Schizophrenia Bulletin 2024, sbae182. PMID: 39488001, DOI: 10.1093/schbul/sbae182.Peer-Reviewed Original ResearchClinical high riskClinical high-risk participantsClinical high-risk researchPremorbid functioningResilient outcomesProtective factorsClinical high-risk youthClinical high-risk populationsReduced startle reactivityPrediction of psychosisAssociated with greater resilienceHigh-risk youthStudy of protective factorsStartle reactivityPsychotic conversionBrain areasPsychosisChildhood environmentBrain developmentGreater resilienceExploratory analysisLife experiencesPreventive interventionsSocial engagementHispanic heritage
2018
Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment
Mereish EH, Padovano HT, Wemm S, Miranda R. Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment. Psychopharmacology 2018, 235: 1933-1943. PMID: 29623354, PMCID: PMC6015780, DOI: 10.1007/s00213-018-4890-z.Peer-Reviewed Original ResearchConceptsCue-elicited cravingStartle reactivityEcological momentary assessment protocolHuman laboratoryCannabis-related stimuliCannabis-related cuesFrequent cannabis usersCross-level interactionsCannabis cuesResultsMultilevel modelsDrug cuesMotivational processesResponse patternsMotivational systemsPicture cuesPleasant stimuliStartle modulationCannabis usersCannabis useCuesStartle magnitudeCravingReal-world environmentsAge 16Startle reflex
1994
Effects of ethanol on the acoustic startle reflex in humans
Grillon C, Sinha R, O'Malley S. Effects of ethanol on the acoustic startle reflex in humans. Psychopharmacology 1994, 114: 167-171. PMID: 7846199, DOI: 10.1007/bf02245459.Peer-Reviewed Original ResearchConceptsEffects of ethanolStartle responsePrepulse inhibitionPrepulse stimulusStartle reflexHealthy normal subjectsAcoustic startle reflexAcoustic startle responseAcute ethanolSensorimotor reactivityNormal subjectsStartle amplitudeStartle reactivitySeparate daysReflex experimentsReflexStartle probesInhibitionStimuliPlaceboResponse
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