2021
The mutational landscape of human somatic and germline cells
Moore L, Cagan A, Coorens T, Neville M, Sanghvi R, Sanders M, Oliver T, Leongamornlert D, Ellis P, Noorani A, Mitchell T, Butler T, Hooks Y, Warren A, Jorgensen M, Dawson K, Menzies A, O’Neill L, Latimer C, Teng M, van Boxtel R, Iacobuzio-Donahue C, Martincorena I, Heer R, Campbell P, Fitzgerald R, Stratton M, Rahbari R. The mutational landscape of human somatic and germline cells. Nature 2021, 597: 381-386. PMID: 34433962, DOI: 10.1038/s41586-021-03822-7.Peer-Reviewed Original ResearchConceptsCell typesMutational landscapeRate of mutationLow rate of cell divisionRate of cell divisionBasal spermatogoniaGermline cellsGenetic variationCell divisionHuman cellsMutational signaturesGermlineAcquired mutationsMutationsSpermatogoniaHuman populationCellsIndividual's lifetimeSBS5/40SpermSBS18Stem cellsSBS1LandscapeType
2012
Epab and Pabpc1 Are Differentially Expressed During Male Germ Cell Development
Ozturk S, Guzeloglu-Kayisli O, Demir N, Sozen B, Ilbay O, Lalioti MD, Seli E. Epab and Pabpc1 Are Differentially Expressed During Male Germ Cell Development. Reproductive Sciences 2012, 19: 911-922. PMID: 22814100, PMCID: PMC4046314, DOI: 10.1177/1933719112446086.Peer-Reviewed Original ResearchConceptsRound spermatidsGene expressionMale germ cell developmentGerm cell developmentPABPC1 expressionTranslational regulationCytoplasmic polyadenylationPosttranscriptional mechanismsPABPC1Key proteinsCell developmentEPABSpatial expressionMature testesMouse testisMessenger RNASpermatogenic cellsTail lengthProteinSpermatocytesExpressionSpermatogoniaTestisEarly postnatal lifePolyadenylation
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