Upregulation of matrix metalloproteinases and inflammatory mediators are associated with abdominal aortic aneurysm induction in a porcine model
Khare G, Rhee S, Hynecek R, DeRubertis B, Kent K, Faries P. Upregulation of matrix metalloproteinases and inflammatory mediators are associated with abdominal aortic aneurysm induction in a porcine model. The FASEB Journal 2007, 21: a1129-a1129. DOI: 10.1096/fasebj.21.6.a1129-b.Peer-Reviewed Original ResearchAbdominal aortic aneurysmPorcine modelMatrix metalloproteinasesEndovascular treatment strategiesNormal aortic tissueMale Yorkshire swineDays post inductionKey matrix metalloproteinasesCDNA expression profilesAneurysm inductionInflammatory mediatorsGene chip arrayInflammatory cytokinesAortic aneurysmAAA formationLocal perfusionTreatment strategiesAAA pathogenesisMechanical dilationAortic tissueExpression profilesTissue inhibitorAAA tissueYorkshire swineSerine protease levels
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