The expression of essential selenoproteins during development requires SECIS-binding protein 2–like
Kiledjian N, Shah R, Vetick M, Copeland P. The expression of essential selenoproteins during development requires SECIS-binding protein 2–like. Life Science Alliance 2022, 5: e202101291. PMID: 35210313, PMCID: PMC8881744, DOI: 10.26508/lsa.202101291.Peer-Reviewed Original ResearchConceptsSECIS-binding protein 2Sec insertion sequenceSelenoprotein synthesisProtein 2Amino acid selenocysteineFrame UGA codonDays post fertilizationEssential selenoproteinsCRISPR mutationsSec incorporationUGA codonSelenoprotein mRNAsPost fertilizationRNA structureSe labelingSelenoproteinsFull complementInsertion sequenceEmbryosCodonGenesSBP2Oxidative stressDietary requirementsRelative roles
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