Brain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths
Zugman A, Ringlein G, Finn E, Lewis K, Berman E, Silverman W, Lebowitz E, Pine D, Winkler A. Brain functional connectivity and anatomical features as predictors of cognitive behavioral therapy outcome for anxiety in youths. Psychological Medicine 2025, 55: e91. PMID: 40125734, PMCID: PMC12080668, DOI: 10.1017/s0033291724003131.Peer-Reviewed Original ResearchConceptsCognitive-behavioral therapyConnectome predictive modelingWeeks of cognitive-behavioral therapyCognitive behavioural therapy outcomeResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingBehaviour therapy outcomePediatric anxiety disordersBaseline anxiety severityBrain functional connectivityAnxiety disordersAnxiety severityPediatric anxietyAnxiety diagnosesAnxiety symptomsFunctional connectivityTherapy outcomeAnxietyFirst-line treatmentTreatment responseTreatment outcomesMagnetic resonance imagingPredictive of responseFirst-lineClinical outcomes
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