2025
Diagnosis of Fibrosis with Magnetization-Prepared Golden-angle RAdial Sparse Parallel (MP-GRASP) T1Mapping in Renal Allografts
Bane O, Feng L, Xia D, Liu M, Bolger I, Calle S, Dyke J, Menon M, Seshan S, Salvatore S, Stillman I, Muthukumar T, Farouk S, Taouli B, Lewis S. Diagnosis of Fibrosis with Magnetization-Prepared Golden-angle RAdial Sparse Parallel (MP-GRASP) T1Mapping in Renal Allografts. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/4462.Peer-Reviewed Original ResearchRenal allograft fibrosisAllograft fibrosisRenal functionDiagnostic performanceRenal transplant recipientsDiagnosis of fibrosisGolden-angle radial sparse parallelRenal T1Variable flip angle T1 mappingFunctioning allograftEGFR declineTransplant recipientsRenal allograftsRenal transplantationT1 mapping methodDiagnostic sensitivityRenal fibrosisFibrosisT1 mappingPatientsAllograftRadial acquisitionAngle acquisitionVariable flip angle methodBiopsy
2014
Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis
Menon MC, Chuang PY, Li Z, Wei C, Zhang W, Luan Y, Yi Z, Xiong H, Woytovich C, Greene I, Overbey J, Rosales I, Bagiella E, Chen R, Ma M, Li L, Ding W, Djamali A, Saminego M, O’Connell P, Gallon L, Colvin R, Schroppel B, He JC, Murphy B. Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis. Journal Of Clinical Investigation 2014, 125: 208-221. PMID: 25437874, PMCID: PMC4382250, DOI: 10.1172/jci76902.Peer-Reviewed Original ResearchMeSH KeywordsAllograftsAnimalsbeta CateninDisease SusceptibilityEnhancer Elements, GeneticFibrosisGene ExpressionGenetic Association StudiesGenetic LociHEK293 CellsHumansIntronsKidneyKidney DiseasesKidney TransplantationMaleMiceMicrofilament ProteinsPolymorphism, Single NucleotideQuantitative Trait LociRiskSmad3 ProteinTranscription Factor 7-Like 2 ProteinTranscriptional ActivationTransforming Growth Factor beta1ConceptsChronic allograft nephropathyChronic kidney diseaseAllograft fibrosisTGF-β1Development of CANRisk allelesKidney transplant recipientsRenal allograft recipientsGlomerular filtration rateRenal allograft fibrosisTGF-β1 administrationUnilateral ureteric obstructionRenal tubular cellsTranscription factor 7Canonical TGF-β1Cell-specific knockdownAllograft injuryAllograft nephropathyAllograft recipientsTransplant recipientsProspective cohortRenal functionInterstitial fibrosisUreteric obstructionKidney disease
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