A whole-brain voxel based measure of intrinsic connectivity contrast reveals local changes in tissue connectivity with anesthetic without a priori assumptions on thresholds or regions of interest
Martuzzi R, Ramani R, Qiu M, Shen X, Papademetris X, Constable RT. A whole-brain voxel based measure of intrinsic connectivity contrast reveals local changes in tissue connectivity with anesthetic without a priori assumptions on thresholds or regions of interest. NeuroImage 2011, 58: 1044-1050. PMID: 21763437, PMCID: PMC3183817, DOI: 10.1016/j.neuroimage.2011.06.075.Peer-Reviewed Original ResearchConceptsIntrinsic connectivity contrastBrain circuitsFunctional connectivity fMRISpontaneous fluctuationsFunctional magnetic resonance imaging (fMRI) signalsWhole-brain voxelDifferent brain circuitsConnectivity analysisMagnetic resonance imaging signalsSevoflurane anesthesiaIntrinsic connectivityIndividual tissue elementsICC analysisICC measuresRegion of interestTissue elementsFMRI signalsBrainNon-invasive mannerFunctional organizationImaging signalsSeed regionSingle seed regionTissue connectivityPrevious studies