2019
Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy
Latif SR, Nguyen VQ, Peters DC, Soufer A, Henry ML, Grunseich K, Testani J, Hur DJ, Huber S, Mojibian H, Dicks D, Sinusas AJ, Meadows JL, Papoutsidakis N, Jacoby D, Baldassarre LA. Left atrial fibrosis correlates with extent of left ventricular myocardial delayed enhancement and left ventricular strain in hypertrophic cardiomyopathy. The International Journal Of Cardiovascular Imaging 2019, 35: 1309-1318. PMID: 30790116, DOI: 10.1007/s10554-019-01551-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAtrial Function, LeftAtrial RemodelingCardiomyopathy, HypertrophicContrast MediaFemaleFibrosisHeart AtriaHeart VentriclesHumansHypertrophy, Left VentricularMagnetic Resonance Imaging, CineMaleMiddle AgedOrganometallic CompoundsPredictive Value of TestsRetrospective StudiesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsLA fibrosisLV-LGEHypertrophic cardiomyopathyLA-LGELV fibrosisLV parametersLV end-diastolic volumeSetting of HCMAldosterone system inhibitionLate gadolinium enhancement (LGE) sequencesLV global strainLeft ventricular massEnd-diastolic volumeLeft atrial fibrosisMaximum wall thicknessFibrosis correlatesRenin-AngiotensinVentricular strainMedication usageAtrial fibrosisLV remodelingVentricular massLV massSystem inhibitionDiastolic volumePrognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2018
Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure
Seemann F, Baldassarre LA, Llanos‐Chea F, Gonzales RA, Grunseich K, Hu C, Sugeng L, Meadows J, Heiberg E, Peters DC. Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure. Physiological Reports 2018, 6: e13828. PMID: 30187654, PMCID: PMC6125607, DOI: 10.14814/phy2.13828.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementMagnetic resonance imagingPulmonary capillary wedge pressureLA late gadolinium enhancementCapillary wedge pressureTransthoracic echocardiographyDiastolic functionDiastolic parametersWedge pressureAtrial remodelingFilling pressureCardiovascular magnetic resonance imagingLeft atrial remodelingVentricular filling pressureAtrial late gadolinium enhancementLGE-magnetic resonance imagingDiastolic dysfunctionMedical chartsLA volumeAtrial fibrosisGadolinium enhancementResonance imagingPressure catheterizationLow interobserverEchocardiography
2016
T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1
Hu C, Sinusas AJ, Huber S, Thorn S, Stacy MR, Mojibian H, Peters DC. T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1. Journal Of Cardiovascular Magnetic Resonance 2016, 19: 63. PMID: 28821300, PMCID: PMC5563030, DOI: 10.1186/s12968-017-0375-1.Peer-Reviewed Original ResearchAlgorithmsAnimalsCardiomyopathiesComputer SimulationContrast MediaFeasibility StudiesFemaleFibrosisHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedModels, CardiovascularMonte Carlo MethodOrganometallic CompoundsPhantoms, ImagingPredictive Value of TestsReproducibility of ResultsSus scrofaCMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation
Peters DC, Duncan JS, Grunseich K, Marieb MA, Cornfeld D, Sinusas AJ, Chelikani S. CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation. JACC Cardiovascular Imaging 2016, 10: 207-208. PMID: 27085430, PMCID: PMC5600154, DOI: 10.1016/j.jcmg.2016.01.015.Peer-Reviewed Original Research
2013
Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2009
Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy
Han Y, Peters DC, Dokhan B, Manning WJ. Shorter difference between myocardium and blood optimal inversion time suggests diffuse fibrosis in dilated cardiomyopathy. Journal Of Magnetic Resonance Imaging 2009, 30: 967-972. PMID: 19856417, PMCID: PMC2862561, DOI: 10.1002/jmri.21953.Peer-Reviewed Original ResearchConceptsDCM patientsDiffuse fibrosisCardiovascular magnetic resonance studyLGE CMR imagesCardiomyopathy patientsHealthy controlsHealthy subjectsLGE-CMRHeart ratePatientsFibrosisOptimal inversion timeBloodMyocardiumMyocardium contrastInversion timeShort differencesBlood signalBlood SNRDCMOptimal timeLower CNR
2008
Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse
Han Y, Peters DC, Salton CJ, Bzymek D, Nezafat R, Goddu B, Kissinger KV, Zimetbaum PJ, Manning WJ, Yeon SB. Cardiovascular Magnetic Resonance Characterization of Mitral Valve Prolapse. JACC Cardiovascular Imaging 2008, 1: 294-303. PMID: 19356441, DOI: 10.1016/j.jcmg.2008.01.013.Peer-Reviewed Original ResearchMeSH KeywordsArrhythmias, CardiacCase-Control StudiesContrast MediaEchocardiography, DopplerFibrosisGadolinium DTPAHumansImaging, Three-DimensionalMagnetic Resonance Imaging, CineMitral ValveMitral Valve ProlapsePapillary MusclesPredictive Value of TestsProspective StudiesSensitivity and SpecificityConceptsMitral valve prolapseComplex ventricular arrhythmiasMVP patientsMitral annular diameterValve prolapseControl subjectsPapillary musclesTransthoracic echocardiographyVentricular arrhythmiasAnnular diameterDiagnostic criteriaCardiovascular magnetic resonance characterizationCommon valvular heart diseaseLeft ventricular outflow tractCMR diagnostic criteriaSubgroup of patientsValvular heart diseaseVentricular outflow tractGold standardLate gadolinium enhancementCardiovascular magnetic resonanceMitral valve morphologyValuable imaging toolClinical gold standardControl patients