2024
In vivo neuropil density from anatomical MRI and machine learning
Akif A, Staib L, Herman P, Rothman D, Yu Y, Hyder F. In vivo neuropil density from anatomical MRI and machine learning. Cerebral Cortex 2024, 34: bhae200. PMID: 38771239, PMCID: PMC11107380, DOI: 10.1093/cercor/bhae200.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingSynaptic densityNeuropil densityCellular densityArtificial neural networkNeural networkPositron emission tomographyAnatomical magnetic resonance imagingHealthy subjectsSynaptic activityMRI scansMachine learning algorithmsBrain's energy budgetEmission tomographyIn vivo MRI scansResonance imagingTissue cellularityLearning algorithmsDiffusion magnetic resonance imagingMachine learningMicroscopic interpretationInterpretation of functional neuroimaging dataIndividual predictionsSubjects
2001
Automated measurement of latent morphological features in the human corpus callosum
Peterson B, Feineigle P, Staib L, Gore J. Automated measurement of latent morphological features in the human corpus callosum. Human Brain Mapping 2001, 12: 232-245. PMID: 11241874, PMCID: PMC6871880, DOI: 10.1002/1097-0193(200104)12:4<232::aid-hbm1018>3.0.co;2-j.Peer-Reviewed Original ResearchConceptsCorpus callosumSubject characteristicsYears of ageHuman corpus callosumPatient groupCallosum sizeHealthy subjectsMRI scansVentricular volumeCallosumMidsagittal planeFactor scoresNeural correlatesConstruct validityFactor-based analysisConventional measuresFuture studiesMorphological featuresAgePredictive validitySubjectsScoresNormal developmentVarimax rotationFactors
2000
Hippocampal Volume Reduction in Major Depression
Bremner J, Narayan M, Anderson E, Staib L, Miller H, Charney D. Hippocampal Volume Reduction in Major Depression. American Journal Of Psychiatry 2000, 157: 115-118. PMID: 10618023, DOI: 10.1176/ajp.157.1.115.Peer-Reviewed Original ResearchConceptsSmaller left hippocampal volumeLeft hippocampal volumeHippocampal volumeMajor depressionComparison subjectsHippocampal volume reductionWhole brain volumeMagnetic resonance imagingNondepressed comparison subjectsAlcohol exposureBrain areasBrain volumeResonance imagingPatientsElevated levelsDepressionHippocampusVolume reductionComparison regionBrain sizeSubjectsRemissionGlucocorticoidsFindings