2023
Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning
Kucukkaya A, Zeevi T, Chai N, Raju R, Haider S, Elbanan M, Petukhova-Greenstein A, Lin M, Onofrey J, Nowak M, Cooper K, Thomas E, Santana J, Gebauer B, Mulligan D, Staib L, Batra R, Chapiro J. Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning. Scientific Reports 2023, 13: 7579. PMID: 37165035, PMCID: PMC10172370, DOI: 10.1038/s41598-023-34439-7.Peer-Reviewed Original Research
2020
Automated detection and delineation of hepatocellular carcinoma on multiphasic contrast-enhanced MRI using deep learning
Bousabarah K, Letzen B, Tefera J, Savic L, Schobert I, Schlachter T, Staib LH, Kocher M, Chapiro J, Lin M. Automated detection and delineation of hepatocellular carcinoma on multiphasic contrast-enhanced MRI using deep learning. Abdominal Radiology 2020, 46: 216-225. PMID: 32500237, PMCID: PMC7714704, DOI: 10.1007/s00261-020-02604-5.Peer-Reviewed Original ResearchConceptsDeep convolutional neural networkAverage false positive rateDice similarity coefficientU-NetDeep learning algorithmsConvolutional neural networkTest setMean Dice similarity coefficientRandom forest classifierDCNN methodDCNN approachDeep learningNet architectureLearning algorithmNeural networkLiver segmentationManual 3D segmentationForest classifierGround truthManual segmentationFalse positive rateCorresponding segmentationSegmentationMultiphasic contrast-enhanced MRIThresholding
2019
Generalizable Multi-Site Training and Testing Of Deep Neural Networks Using Image Normalization
Onofrey JA, Casetti-Dinescu DI, Lauritzen AD, Sarkar S, Venkataraman R, Fan RE, Sonn GA, Sprenkle PC, Staib LH, Papademetris X. Generalizable Multi-Site Training and Testing Of Deep Neural Networks Using Image Normalization. 2011 IEEE International Symposium On Biomedical Imaging: From Nano To Macro 2019, 00: 348-351. PMID: 32874427, PMCID: PMC7457546, DOI: 10.1109/isbi.2019.8759295.Peer-Reviewed Original ResearchDeep neural networksNeural networkDeep learning algorithmsProstate gland segmentationImage normalization methodGland segmentationLearning algorithmImage normalizationMulti-site dataIntensity normalization methodNormalization methodSingle-site dataAlgorithmNetworkPotential solutionsEquipment sourcesClinical adoptionSegmentationTrainingIntensity characteristicsRobustnessDataSite trainingMethodAdoption