Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsWilliam Bradlyn Laskin, MD
Clinical ProfessorAbout
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Biography
After graduation from the United States Naval Academy at Annapolis in 1973, Dr. Laskin served two years on the destroyer, USS Corry (DD-817) as Gunnery Officer. He then earned his MD in 1979 from Jefferson Medical College in Philadelphia through the Navy Medical/Osteopathic Scholarship Program. Dr. Laskin completed his Anatomic and Clinical Pathology residency at Bethesda Naval Hospital (now known as Walter Reed National Military Medical Center) and was board certified in 1984. His Navy Medical Corps career included clinical leadership positions at the Armed Forces Institute of Pathology, the National Naval Medical Center, and Naval Hospital Japan, as well as faculty positions at the Uniformed Services University of the Health Sciences from 1990-1996. He was a member of the pathology faculty at Northwestern Feinberg School of Medicine in Chicago from 1996 to 2015, and served for a time as head of surgical pathology at Northwestern Memorial Hospital. Dr. Laskin joined the Pathology Department at Yale Medical School in 2015 as an Associate Professor.
Appointments
Pathology
Clinical ProfessorPrimary
Other Departments & Organizations
- Bone & Soft Tissue Pathology
- Pathology
- Sarcoma Program
- Surgical Pathology
- Yale Cancer Center
Education & Training
- Resident
- Bethesda Naval Hospital (1984)
- MD
- Jefferson Medical College (1979)
- BS
- United States Naval Academy, Chemistry (1973)
Research
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Overview
Medical Research Interests
ORCID
0000-0003-3991-3993
Research at a Glance
Yale Co-Authors
Publications Timeline
Hao Wu, MD, PhD
Dieter Lindskog, MD
Hari Deshpande, MD
Haiying Zhan, MD, PhD
Jeffrey Townsend, PhD
Jennifer Madison McNiff, MD
Publications
2026
Mycobacterial Spindle Cell Pseudotumor Presenteing as an Aggressive Lytic Lesion in the Tibia in an Immunocompromised Patient.
Wu H, Lindskog D, Laskin W. Mycobacterial Spindle Cell Pseudotumor Presenteing as an Aggressive Lytic Lesion in the Tibia in an Immunocompromised Patient. International Journal Of Surgical Pathology 2026, 10668969261422273. PMID: 41834387, DOI: 10.1177/10668969261422273.Peer-Reviewed Original ResearchConceptsSpindle cell pseudotumorMycobacterial spindle cell pseudotumorImmunocompromised patientsGranuloma formationSpindle-shaped histiocytesAtypical mycobacterial infectionLytic bone lesionsTumor-like proliferationAggressive lytic lesionGMS stainsLymph nodesLytic lesionsBone lesionsDifferential diagnosisDiagnostic considerationsOsseous lesionsMicrobiological cultureMycobacterial infectionAccurate diagnosisSpindled histiocytesNeoplastic conditionsPseudotumorTibial lesionsLesionsPatientsTuberculosis of the wrist- I Wasn't in good hands
Haroon J, Donohue K, Laskin W, Golden M. Tuberculosis of the wrist- I Wasn't in good hands. Journal Of Orthopaedic Reports 2026, 5: 100654. DOI: 10.1016/j.jorep.2025.100654.Peer-Reviewed Original Research
2025
Metastatic Breast Cancer to a Dedifferentiated Solitary Fibrous Tumor Arising from a PTEN Hamartoma of Soft Tissue
Jiao J, Lindskog D, Laskin W, Wu H. Metastatic Breast Cancer to a Dedifferentiated Solitary Fibrous Tumor Arising from a PTEN Hamartoma of Soft Tissue. International Journal Of Surgical Pathology 2025, 33: 1856-1861. PMID: 40452397, DOI: 10.1177/10668969251343903.Peer-Reviewed Case Reports and Technical NotesAltmetricConceptsDedifferentiated solitary fibrous tumorSolitary fibrous tumorPTEN hamartoma of soft tissueBreast cancerSoft tissueAssociated with other neoplasmsConventional solitary fibrous tumorMetastatic breast carcinomaGermline pathogenic variantsMetastatic breast cancerMetastatic ductal carcinomaPTEN hamartoma tumor syndromePlump spindle cellsDeep soft tissuesHamartoma tumor syndromePostzygotic mosaicismThin-walled vesselsPathogenic variantsPatternless patternFibrous tumorDuctal carcinomaBreast carcinomaGermline mutationsPediatric lesionsMyxoid background
2024
Use of Mitotic Activity and the Size of Any Dedifferentiated Component for Risk Assessment in MDM2-Amplified Liposarcoma.
Wu H, Sukhanova M, Tang H, Lu X, Zhong M, Deshpande H, Pollack S, Laskin W, Alexiev B. Use of Mitotic Activity and the Size of Any Dedifferentiated Component for Risk Assessment in MDM2-Amplified Liposarcoma. Archives Of Pathology & Laboratory Medicine 2024, 149: 422-430. PMID: 39164013, DOI: 10.5858/arpa.2024-0098-oa.Peer-Reviewed Original ResearchCitationsConceptsAtypical lipomatous tumor/well-differentiated liposarcomaMDM2-amplified liposarcomasDedifferentiated componentDedifferentiated liposarcomaAdverse eventsMitotic countLocal recurrence statusMDM2 copy numberAssociated with adverse eventsLog-rank testOverall tumor volumeUnivariate logistic regressionChromosome 12q13-15Statistically significant associationPercentage of cellsTumor dimensionTumor volumeTumor sizeMDM2 proto-oncogeneClinicopathological characteristicsPathology reportsGrade 3Recurrence statusUnivariate analysisMultivariate regression modelGenomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature
Kaseb H, Tan C, Townsend J, Costa J, Laskin W. Genomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature. Genetic Testing And Molecular Biomarkers 2024, 28: 351-359. PMID: 39052504, DOI: 10.1089/gtmb.2024.0080.Peer-Reviewed Original ResearchCitationsConceptsWhole-exome sequencingTumor mutational burdenOsteosarcoma of boneMutational burdenGenomic landscapeDNA damage repair genesDNA homologous recombination repairLoss of heterozygosityEffects of chemotherapyPathogenic germline mutationsParaffin-embedded tissuesPrimary malignant bone tumorAnalysis of single nucleotide variantsMalignant bone tumorsRecombination repairMutagenic processesMolecular aberrationsOlder adult patientsAdult patientsSingle nucleotide variantsDNA recombinational repairGermline mutationsTumor pathogenesisFormalin-FixedHomologous recombination repairAdenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma
Tang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024, 51: 604-608. PMID: 38711196, DOI: 10.1111/cup.14639.Peer-Reviewed Original ResearchCitationsConceptsEncapsulated papillary carcinomaDuctal carcinoma in situAnogenital mammary-like glandsMammary-like glandsInvasive carcinomaPapillary carcinomaBreast lesionsHidradenoma papilliferumLack of myoepithelial cellsInvasive mucinous carcinomaCutaneous adnexal tumorsCarcinoma in situInvasive ductal carcinomaGland typeVulvar tumorsAdnexal tumorsMucinous carcinomaDuctal carcinomaBreast carcinomaInvasive componentPapillary proliferationHistopathological featuresRare caseSkin tumorsCystic spacesAn Unexpected Finding: A Progressive Case of Thoracic Sarcoma
Campana M, Mogica J, Laskin W, Deshpande H. An Unexpected Finding: A Progressive Case of Thoracic Sarcoma. American Journal Of Respiratory And Critical Care Medicine 2024, 209: a6534-a6534. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6534.Peer-Reviewed Original Research
2023
Myxoinflammatory Fibroblastic Sarcoma
Wu H, Laskin W. Myxoinflammatory Fibroblastic Sarcoma. Surgical Pathology Clinics 2023, 17: 83-96. PMID: 38278610, DOI: 10.1016/j.path.2023.07.003.ChaptersCitationsAltmetricClear cell chondrosarcoma: a review of clinicopathologic characteristics, differential diagnoses, and patient management
Alexiev B, Vormittag-Nocito E, Peabody T, Samet J, Laskin W. Clear cell chondrosarcoma: a review of clinicopathologic characteristics, differential diagnoses, and patient management. Human Pathology 2023, 139: 126-134. PMID: 37805864, DOI: 10.1016/j.humpath.2023.06.004.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsClear cell chondrosarcomaDiagnosis of clear cell chondrosarcomaPrimary bone tumorsDiagnostic accuracy of core needle biopsyAccuracy of core needle biopsyBone tumorsRarest primary bone tumorsLocal recurrence rateAbundant clear cytoplasmCore needle biopsyRate of recurrenceYounger patient ageLow-grade chondrosarcomaSkeletally Immature PatientsMalignant cartilaginous neoplasmsDecades of lifeEpiphysis of long bonesLow diagnostic accuracyOperative resectionIncomplete excisionNeedle biopsyHistopathological diagnosisPatient ageRecurrence rateClinicopathological characteristics
2019
Soft Tissue Lesions Involving Female Reproductive Organs
Fetsch J, Laskin W. Soft Tissue Lesions Involving Female Reproductive Organs. 2019, 1405-1467. DOI: 10.1007/978-3-319-46334-6_22.Peer-Reviewed Original ResearchCitationsConceptsFemale reproductive organsCommon benign mesenchymal tumorsMalignant mesenchymal neoplasmArmed Forces InstituteSoft tissue lesionsBenign mesenchymal tumorsGynecologic tractAdult patientsTumor RegistryMesenchymal tumorsReproductive organsMesenchymal neoplasmsMesenchymal processesRarer lesionsTissue lesions
Academic Achievements & Community Involvement
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Honors
honor Alpha Omega Alpha
06/01/1979National AwardJefferson Medical CollegeDetailsUnited States
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