Nalan Yurtsever, MD
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Titles
Assistant Professor of Laboratory Medicine
Medical Director of Clinical Labs, Laboratory Medicine; Assistant Medical Director of Blood Bank, Laboratory Medicine
Biography
Nalan Yurtsever, MD, is a laboratory medicine specialist with expertise in transfusion medicine and apheresis. She currently serves as the Medical Director of the Clinical Laboratory at Bridgeport Hospital and Assistant Medical Director of the blood bank. Dr. Yurtsever is committed to improving laboratory quality to enhance both diagnosis and treatment. Her work aims to advance testing methods and deepen the understanding of transfusion-related challenges to improve patient outcomes.
Appointments
Laboratory Medicine
Assistant ProfessorPrimary
Other Departments & Organizations
- All Institutions
- Laboratory Medicine
- Palade House Affiliates
- Yale Medicine
- Yale New Haven Health System
Education & Training
- MD
- Yale New Haven Hospital, Transfusion Medicine and Apheresis (2024)
- Fellowship
- Yale University School of Medicine (2024)
- MD
- Zucker School of Medicine at Hofstra/Northwell, Anatomic and Clinical Pathology (2023)
- MD
- Ankara University School of Medicine
- Residency
- Zucker School of Medicine at Hofstra/Northwell
Research
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Overview
Research interests include red cell exchange in sickle cell patients, transfusion reactions, transfusion safety, and red cell antibodies.
ORCID
0000-0001-7807-6046
Research at a Glance
Yale Co-Authors
Publications Timeline
Christopher Tormey, MD
Henry Rinder, MD
Erin Horstman, MD
Alexa Siddon, MD
Edward L. Snyder, MD, FACP
Hongyan Chai
Publications
2025
Reevaluating Ferritin Reference Intervals: Defining Limits Based on Iron-Sufficient Population Studies, Clinical Relevance, and Healthcare Efficiency
Kodger J, El-Khoury J, Yurtsever N. Reevaluating Ferritin Reference Intervals: Defining Limits Based on Iron-Sufficient Population Studies, Clinical Relevance, and Healthcare Efficiency. The Journal Of Applied Laboratory Medicine 2025, jfaf151. PMID: 41047906, DOI: 10.1093/jalm/jfaf151.Peer-Reviewed Original ResearchLoss of D expression associated with hematologic disease progression: a case report and review of the literature
Yurtsever N, Carmichael G, Li P, Di Wen J, Chai H, Diadamo A, Denomme G, Tormey C. Loss of D expression associated with hematologic disease progression: a case report and review of the literature. Immunohematology 2025, 41: 80-83. PMID: 41168989, DOI: 10.2478/immunohematology-2025-012.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsStem cell transplantationPatient's red blood cellsMyelodysplastic syndromeCell transplantationRed blood cellsPolymerase chain reactionPre-B acute lymphocytic leukemiaColon cancerGroup AAllogeneic stem cell transplantationHigh-risk myelodysplastic syndromeInitiation of immunosuppressive therapyDiagnosis of myelodysplastic syndromeChromosomal microarrayAcute lymphocytic leukemiaSanger sequencingFemale cellsPartial D variantsGene expressionImmunosuppressive therapyLymphocytic leukemiaD phenotypeMale patientsCase reportAnti-D reagentsWhy auto‐anti‐D might be more likely than allo‐anti‐D for people with conventional D type
Yurtsever N, Liu J, Cedeno E, Tormey C, Denomme G, Horstman E. Why auto‐anti‐D might be more likely than allo‐anti‐D for people with conventional D type. British Journal Of Haematology 2025, 207: 1722-1725. PMID: 41070675, DOI: 10.1111/bjh.70081.Peer-Reviewed Original ResearchEvaluating RhD assessment by automated methodology: A potential “blind spot” for RhD variant identification
Yurtsever N, Tormey C, Bizzario L, Lee E. Evaluating RhD assessment by automated methodology: A potential “blind spot” for RhD variant identification. Transfusion 2025, 65: 1574-1579. PMID: 40944507, DOI: 10.1111/trf.18343.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPositive predictive valueRHD genotypingD variantsWomen of Childbearing AgeRHD variant allelesHigh-risk patientsYale-New Haven HospitalAnti-D formationBlood bank protocolsTube testAnti-D AntibodiesNew Haven HospitalRh blood groupsChildbearing ageVariant allelesPatient populationTransfusion practicePatientsTraditional tube testsPredictive valueTransfusionBlood groupTransfusion servicesRHDSerological reactivity“Cryobit” aggregates in liquid plasma units
Gereg C, Tormey C, West F, Yurtsever N. “Cryobit” aggregates in liquid plasma units. Transfusion 2025, 65: 1383-1384. PMID: 40485613, DOI: 10.1111/trf.18308.Peer-Reviewed Original ResearchMedical, Societal, and Ethical Considerations for Directed Blood Donation in 2025.
Jacobs J, Booth G, Lewis-Newby M, Saifee N, Ferguson E, Cohn C, Delaney M, Morley S, Thomas S, Thorpe R, Raza S, Weaver M, Woo J, Sharma D, So-Osman C, Yurtsever N, Tormey C, Waters A, Goldman M, Yan M, Fasano R, Stephens L, Allen E, Erikstrup C, Infanti L, Schlafer T, Warner M, Winters J, Tobian A, Bloch E. Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025. Annals Of Internal Medicine 2025, 178: 1021-1026. PMID: 40354666, DOI: 10.7326/annals-25-00815.Peer-Reviewed Original ResearchCitationsAltmetricConceptsDirected donationEthical principlesEthical concernsEthical considerationsLegislative attemptsPersonal beliefsLegislative effortsPublic trustMandate complianceDiscriminatory practicesScientific justificationDonation preferencesExacerbate shortagesScientific communityMedical necessityDonationPotential harmUnited StatesDirected blood donationsAllocation practicesEthicsLogistical burdenNon-evidence-based interventionsPatient safety risksBlood donationEvaluation of nonspecific reactivity rates across three immunohematology testing platforms with assessment of subsequent specific alloantibody development
Yurtsever N, Carmichael G, Malonis R, Madden M, Isik N, Ahmed M, Bizzario L, Shah B, Tormey C, Lee E. Evaluation of nonspecific reactivity rates across three immunohematology testing platforms with assessment of subsequent specific alloantibody development. Transfusion 2025, 65: 978-984. PMID: 40251842, PMCID: PMC12092180, DOI: 10.1111/trf.18256.Peer-Reviewed Original ResearchCitationsConceptsNonspecific reactivityAntibody screeningStrength of reactivityRate of positivityReagent red cellsAlloantibody developmentKruskal-Wallis testAntibody historyChart reviewPretransfusion testingAntibody identificationIRB approvalIdentification panelKruskal-WallisPositive screenAntibody detectionRed cellsAntibodiesAlloantibodiesStudy periodReactivation rateTube testNonspecific reactionsScreeningCellsMisoprostol administration mimicking a febrile transfusion reaction
Yurtsever N, Snyder E. Misoprostol administration mimicking a febrile transfusion reaction. Transfusion 2025, 65: 643-646. PMID: 39907501, DOI: 10.1111/trf.18150.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsFebrile nonhemolytic transfusion reactionsTransfusion reactionsBlood culturesSynthetic prostaglandin E1 analogueThermogenic effectAdministration of misoprostolProstaglandin E1 analogueRed cell transfusionTransfusion medicineFebrile transfusion reactionsNonhemolytic transfusion reactionsG1P0 femaleMisoprostol administrationCell transfusionE1 analogueChart reviewSerological workupCase reportDifferential diagnosisEnhance patient satisfactionMisoprostolTransfusionUterotonic propertiesSerological findingsSide effects
2024
Prophylactic Red Cell Exchange: Preventing Complications in Pregnant Patients with Sickle Cell Disease
Sariipek N, Horstman E, Tormey C, Yurtsever N. Prophylactic Red Cell Exchange: Preventing Complications in Pregnant Patients with Sickle Cell Disease. Blood 2024, 144: 5340-5340. DOI: 10.1182/blood-2024-198650.Peer-Reviewed Original ResearchConceptsRed cell exchangeManagement of pregnancy-related complicationsSickle cell diseasePre-eclampsiaPregnancy-related complicationsCesarean sectionCell diseaseApgar scoreHealthy infantsPainful crisesBilateral retinal vein occlusionAmerican Society for Apheresis guidelinesSpectra Optia apheresis systemHematocrit levelsEmergency cesarean sectionRetinal artery occlusionRetinal vein occlusionBilateral renal infarctionSickle cell-related complicationsHistory of retinopathyPrevent pre-eclampsiaSecond-line therapyTransient vision lossWeeks of gestationPregnancy related complicationsAssessing the Effect of Changing the Average Hematocrit in Red Blood Cell (RBC) Units on the Post- Procedure Hematocrits of Patients Undergoing Erythrocytapheresis
Musante K, Roome L, Yurtsever N, Rinder H, Tormey C, Lee E. Assessing the Effect of Changing the Average Hematocrit in Red Blood Cell (RBC) Units on the Post- Procedure Hematocrits of Patients Undergoing Erythrocytapheresis. American Journal Of Clinical Pathology 2024, 162: s147-s147. DOI: 10.1093/ajcp/aqae129.326.Peer-Reviewed Original ResearchConceptsSickle cell diseaseRed blood cell unitsSickle cell disease patientsRed blood cellsPatient's HctRBC unitsTransfused RBC unitsRetrospective chart reviewTwo-sample t-testChart reviewAdverse eventsMedian numberPre-procedureProphylactic procedureCell diseasePatientsAcademic hospitalAverage hematocritAverage HctBlood cellsHctTransfusion servicesT-testQuality studiesHematocrit
Academic Achievements & Community Involvement
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Clinical Care
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Overview
Nalan Yurtsever, MD, is a laboratory medicine specialist with expertise in transfusion medicine and apheresis. She currently serves as the medical director of the clinical laboratory at Bridgeport Hospital and assistant medical director of its blood bank.
Dr. Yurtsever is committed to improving laboratory quality to enhance both diagnosis and treatment. Her work aims to advance testing methods and deepen the understanding of transfusion-related challenges to improve patient outcomes.
Clinical Specialties
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Locations
Bridgeport Hospital
Academic Office
267 Grant Street, Wing Pathology, Fl 2nd floor
Bridgeport, CT 06610
Milford Hospital
Academic Office
300 Seaside Ave
Milford, CT 06460
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
Events
Everyone David Gibb, MD, PhD