Microenvironment Cell Contribution to Lymphoma Immunity
Kumar D, Xu ML. Microenvironment Cell Contribution to Lymphoma Immunity. Frontiers In Oncology 2018, 8: 288. PMID: 30101129, PMCID: PMC6073855, DOI: 10.3389/fonc.2018.00288.Peer-Reviewed Original ResearchLymphoma-associated macrophagesMesenchymal stem/stromal cellsT cellsLymphoma microenvironmentStromal cellsMarkers of exhaustionImmune checkpoint blockadeRegulatory T cellsEra of immunotherapyNatural killer cellsAnti-tumor effectsStem/stromal cellsLymphoma immunityTim-3Adverse eventsCheckpoint blockadeDendritic cellsImmune dysfunctionKiller cellsPD-1Immune cellsMechanisms of resistanceImmune escapeTumor surveillanceLAG-3Benign lymph node microenvironment is associated with response to immunotherapy
Toki MI, Kumar D, Ahmed FS, Rimm DL, Xu ML. Benign lymph node microenvironment is associated with response to immunotherapy. Precision Clinical Medicine 2020, 3: 44-53. PMID: 35693430, PMCID: PMC8985791, DOI: 10.1093/pcmedi/pbaa003.Peer-Reviewed Original ResearchBenign lymph nodesLymph nodesT cellsQuantitative immunofluorescenceBenign lymphPD-L1Immune checkpoint blockade therapyMultiplexed quantitative immunofluorescenceHigh expressionCheckpoint blockade therapyMacrophage marker expressionSignificant differencesCytotoxic markersBlockade therapyBenign findingsCancer patientsLymphoid tissueImmune surveillanceTreatment responsePostmortem examinationImmunotherapyProliferation indexSplenic tissueB cellsPatients