Andrea Barbieri, MD
Cards
Additional Titles
Residency Program Director, Pathology
Contact Info
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View Doctor ProfileAdditional Titles
Residency Program Director, Pathology
Contact Info
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Residency Program Director, Pathology
Contact Info
About
Titles
Associate Professor of Pathology
Residency Program Director, Pathology
Biography
Andrea Barbieri is an associate professor in the Department of Pathology. She provides clinical care as a surgical pathologist with expertise in endocrine, head and neck, gastrointestinal and liver pathology. She is a Michigan native and received her undergraduate degree from Case Western Reserve University in Cleveland, Ohio and MD from Wayne State University School of Medicine in Detroit, Michigan. She subsequently completed her residency in Pathology and Laboratory Medicine at Yale New Haven Hospital in 2013 and gastrointestinal pathology fellowship at the Medical College of Wisconsin in 2014. She is board certified in anatomic and clinical pathology. She co-leads the Community and Visibility working group of the Dean's Advisory Council on LGBTQI+ Affairs. She serves as the Residency Program Director for the Anatomic and Clinical Pathology residency training program.
Appointments
Pathology
Associate Professor on TermPrimary
Other Departments & Organizations
- Dean's Advisory Council for LGBTQI Affairs
- Directories
- Gastrointestinal (GI) & Liver Pathology
- Head and Neck Cancers Program
- Head, Neck & Endocrine Pathology
- Pancreatic Diseases Program
- Pathology
- Surgical Pathology
- Training in Lab Med and Pathology
- Yale Medicine
- Yale Medicine Outlist
Education & Training
- Fellowship
- Medical College of Wisconsin (2014)
- Residency
- Yale University/Yale-New Haven Hospital (2013)
- MD
- Wayne State University (2009)
- BA
- Case Western Reserve University (2005)
Research
Overview
Medical Research Interests
Public Health Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Manju Prasad, MD, MBBS
Dhanpat Jain, MD
Joanna Gibson, MD, PhD
Martin Kriegel, MD, PhD
Peter Podany
Allen Bale, MD
Pancreatic Neoplasms
Thyroid Gland
Publications
2023
Grading system for medullary thyroid carcinoma; an institutional experience
Podany P, Meiklejohn K, Garritano J, Holt E, Barbieri A, Prasad M, Gilani S. Grading system for medullary thyroid carcinoma; an institutional experience. Annals Of Diagnostic Pathology 2023, 64: 152112. PMID: 36736129, DOI: 10.1016/j.anndiagpath.2023.152112.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsMedullary thyroid carcinomaTwo-tier grading systemDistant metastasisNuclear pleomorphismGrading systemNodal diseaseOverall survivalVascular invasionMTC casesThyroid carcinomaMedullary thyroid carcinoma casesMultivariate Cox regressionThyroid carcinoma casesCohort of casesRisk stratificationCox regressionTumor gradePathology reportsCarcinoma casesInstitutional experienceThyroid malignancyTumor fibrosisHG groupProminent nucleoliRare type
2022
A review of DICER1: structure, function and contribution to disease
Meiklejohn K, Darbinyan A, Barbieri A. A review of DICER1: structure, function and contribution to disease. Diagnostic Histopathology 2022, 28: 329-336. DOI: 10.1016/j.mpdhp.2022.05.004.Peer-Reviewed Original Research
2021
Impact of Transoral Endoscopic Vestibular Approach Thyroidectomy on Pathologic Assessment.
Smith SM, Ahmed M, Carling T, Udelsman R, Adeniran AJ, Gilani S, Prasad ML, Barbieri AL. Impact of Transoral Endoscopic Vestibular Approach Thyroidectomy on Pathologic Assessment. Archives Of Pathology & Laboratory Medicine 2021, 146: 879-885. PMID: 34669921, DOI: 10.5858/arpa.2021-0082-oa.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsPapillary thyroid carcinomaMargin statusFinal diagnosisThyroid carcinomaCytologic diagnosisEndoscopic thyroid resectionUndetermined significance/Surgical resection specimensPreoperative cytologic diagnosisPathologic assessmentClinical followIndolent neoplasmClinicopathologic featuresThyroid resectionVestibular approachMean agePathologic examinationPreoperative imagingTumor sizeResection specimensPathologic parametersMalignant diagnosisFollicular lesionsFollicular neoplasmSurgical pathologyAnaplastic Thyroid Carcinoma: Cytomorphologic Features on Fine-Needle Aspiration and Associated Diagnostic Challenges
Podany P, Abi-Raad R, Barbieri A, Garritano J, Prasad ML, Cai G, Adeniran AJ, Gilani SM. Anaplastic Thyroid Carcinoma: Cytomorphologic Features on Fine-Needle Aspiration and Associated Diagnostic Challenges. American Journal Of Clinical Pathology 2021, 157: 608-619. PMID: 34661606, PMCID: PMC8973262, DOI: 10.1093/ajcp/aqab159.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH Keywords and ConceptsConceptsAnaplastic thyroid carcinomaFine-needle aspirationCytologic featuresATC casesTumor cellsThyroid carcinomaControl groupDiagnosis of ATCAcute inflammatory cellsKey cytologic featuresNuclear membrane irregularitySingle tumor cellsAggressive malignancyInflammatory cellsClinical historyDiagnostic challengePatient prognosisInclusion criteriaNeedle aspirationCytomorphologic featuresEarly diagnosisEpithelioid cytomorphologyNuclear pleomorphismAvailable slidesElectronic databasesEpidermotropic metastasis of squamous cell carcinoma of the tonsil: A case report with molecular confirmation
Li P, Barbieri A, Walther Z, McNiff J, Panse G. Epidermotropic metastasis of squamous cell carcinoma of the tonsil: A case report with molecular confirmation. Journal Of Cutaneous Pathology 2021, 48: 1514-1519. PMID: 34302376, DOI: 10.1111/cup.14108.Peer-Reviewed Case Reports and Technical NotesMeSH Keywords and ConceptsConceptsSquamous cell carcinomaOropharyngeal squamous cell carcinomaCell carcinomaDe novo squamous cell carcinomaPrimary oropharyngeal squamous cell carcinomaTonsillar squamous cell carcinomaTargetable genetic aberrationsLesion biopsy specimensSkin biopsy specimenSkin lesion biopsy specimensMetastatic diseaseEpidermal involvementEpidermotropic metastasesMetastatic lesionsPoor prognosisBiopsy specimenCase reportClinical historyBiopsy specimensSecondary diseaseSkin lesionsTumor originMetastatic specimensMetastasisNeck skinAnaplastic thyroid carcinoma: diagnostic challenges, histopathologic features and ancillary testing
Gilani S, Khan M, Barbieri A, Prasad M. Anaplastic thyroid carcinoma: diagnostic challenges, histopathologic features and ancillary testing. Diagnostic Histopathology 2021, 27: 263-271. DOI: 10.1016/j.mpdhp.2021.03.004.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAnaplastic thyroid carcinomaDiagnostic challengeAggressive thyroid malignancyHigh mortality rateThyroid follicular cellsCompressive symptomsHistopathologic featuresCarcinoma componentThyroid malignancyAncillary testingThyroid carcinomaMortality rateDiagnostic limitationsFollicular cellsHistopathologic variabilityPaucicellular specimensMalignancyMolecular featuresPainCarcinomaSymptomsLower Gastrointestinal Syphilis: Case Series and Literature Review
Ferzacca E, Barbieri A, Barakat L, Olave MC, Dunne D. Lower Gastrointestinal Syphilis: Case Series and Literature Review. Open Forum Infectious Diseases 2021, 8: ofab157. PMID: 34631920, PMCID: PMC8494075, DOI: 10.1093/ofid/ofab157.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAdditional casesCommon physical examination findingsAnal sexual contactLower gastrointestinal symptomsChronic inflammatory infiltrateInflammatory bowel diseasePhysical examination findingsPercent of specimensAnal painAnorectal massAnorectal ulcersNontreponemal titersGastrointestinal symptomsRectal massSyphilis infectionBowel diseaseRare manifestationCase seriesInflammatory infiltrateEarly syphilisExamination findingsImmunodeficiency virusMucosal abnormalitiesMedical records
2020
A Novel Variant in the Calcium‐Sensing Receptor Associated with Familial Hypocalciuric Hypercalcemia and Low‐to‐Normal PTH
Majumdar SK, Jacob T, Bale A, Bailey A, Kwon J, Hughes T, Barbieri AL, Laskin W, Cohen P, Carling TJE. A Novel Variant in the Calcium‐Sensing Receptor Associated with Familial Hypocalciuric Hypercalcemia and Low‐to‐Normal PTH. Case Reports In Endocrinology 2020, 2020: 8752610. PMID: 33062349, PMCID: PMC7555459, DOI: 10.1155/2020/8752610.Peer-Reviewed Case Reports and Technical NotesConceptsFamilial hypocalciuric hypercalcemiaLow urinary calcium excretionUrinary calcium excretionCalcium excretionSerum calciumHypocalciuric hypercalcemiaCalcium-sensing receptor geneElevated set pointOsteitis fibrosa cysticaNovel heterozygous variantElevated calcitriolParathyroid histologyIntact PTHMild hypercalcemiaSubtotal parathyroidectomyFibrosa cysticaPrimary hyperparathyroidismMild elevationNormal PTHClinical manifestationsNovel variantsBony findingsBony lesionsCASR geneParathyroid glandsThyroid tissue outside the thyroid gland: Differential diagnosis and associated diagnostic challenges
Barbieri A, Prasad ML, Gilani SM. Thyroid tissue outside the thyroid gland: Differential diagnosis and associated diagnostic challenges. Annals Of Diagnostic Pathology 2020, 48: 151584. PMID: 32871503, DOI: 10.1016/j.anndiagpath.2020.151584.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsDifferential diagnostic considerationsThyroid tissueThyroid glandLymph nodesDiagnostic challengeDifferential diagnosisDiagnostic considerationsLateral neck lymph nodesNeck lymph nodesRoutine daily practiceThyroglossal duct cystLocation of lesionsMalignant differential diagnosisDuct cystDefinitive diagnosisLingual thyroidAnatomic locationClinical settingThyroid folliclesDaily practiceDiagnosisParasitic nodulesGlandTissueHistologicHistologic Classification and Molecular Signature of Polymorphous Adenocarcinoma (PAC) and Cribriform Adenocarcinoma of Salivary Gland (CASG)
Xu B, Barbieri AL, Bishop JA, Chiosea SI, Dogan S, Di Palma S, Faquin WC, Ghossein R, Hyrcza M, Jo VY, Lewis JS, Lozada JR, Michal M, Pareja FG, Perez-Ordonez B, Prasad ML, Purgina B, Reis-Filho JS, Scognamiglio T, Sebastiao APM, Seethala RR, Skálová A, Smith SM, Tekkeşin MS, Thompson LDR, Wasseman JK, Wenig BM, Weinreb I, Katabi N. Histologic Classification and Molecular Signature of Polymorphous Adenocarcinoma (PAC) and Cribriform Adenocarcinoma of Salivary Gland (CASG). The American Journal Of Surgical Pathology 2020, 44: 545-552. PMID: 31917707, PMCID: PMC7437128, DOI: 10.1097/pas.0000000000001431.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsMeSH KeywordsAdenocarcinomaBiomarkers, TumorBiopsyCanadaDNA Mutational AnalysisEuropeGene FusionGenetic Predisposition to DiseaseHumansIn Situ Hybridization, FluorescenceMutationObserver VariationPredictive Value of TestsReal-Time Polymerase Chain ReactionReproducibility of ResultsSalivary Gland NeoplasmsUnited StatesConceptsPapillary architectureIndeterminate featuresPolymorphous adenocarcinomaConsensus diagnosisCribriform adenocarcinomaInterobserver agreementSalivary glandsFair interobserver agreementNeck pathologistHistologic diversityHistologic classificationMorphologic spectrumDiagnostic concordanceSolid patternMolecular alterationsAdenocarcinomaGlomeruloid structuresTumorsLevel of agreementHotspot mutationsClear nucleiModerate agreementExpert pathologistsSuch molecular eventsMolecular signatures
Academic Achievements & Community Involvement
honor Top Doctors List
Regional AwardCastle ConnollyDetails05/01/2024honor Advanced Emerging Leaders Program
Yale University AwardYale School of ManagementDetails05/01/2024honor Emerging Leaders Program
Yale University AwardYale School of ManagementDetails05/01/2023honor Great Catch Award
Hospital System AwardYale New Haven HospitalDetails06/07/2021honor Medical Education Fellow
Yale School of Medicine AwardDetails06/01/2021United States
Clinical Care
Overview
Andrea Barbieri, MD, is a pathologist who specializes in gastrointestinal, liver, endocrine, and head and neck diseases and cancers.
She developed an early interest in medicine, having heard her father (an interventional radiologist) and mother (an ultrasound technician) discuss medical stories at the dinner table. In medical school, Dr. Barbieri particularly enjoyed lectures on pathology. “Looking at a snapshot of cells and coming up with a cohesive diagnosis felt like solving a puzzle or translating another language,” Dr. Barbieri says.
Dr. Barbieri initially specialized in gastrointestinal and liver pathology, and later gained experience with endocrine and head and neck diseases. “Having knowledge in different areas of pathology is helpful when making diagnoses in a specific area,” she says.
Dr. Barbieri also feels she works closely with patients even though, like all pathologists, she rarely sees them face-to-face. “I feel like a patient advocate, ensuring they get the best and most appropriate care,” she says.
As an assistant professor of pathology at the Yale School of Medicine, Dr. Barbieri conducts research into infectious diseases related to the gastrointestinal tract. Her research also focuses on how to improve the quality of diagnoses in pathology.
Clinical Specialties
Fact Sheets
Head and Neck Cancer
Learn More on Yale Medicine
Board Certifications
Anatomic & Clinical Pathology
- Certification Organization
- AB of Pathology
- Latest Certification Date
- 2013
- Original Certification Date
- 2013
Yale Medicine News
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News
- November 13, 2024
Public School Students Explore Careers at Annual Yale Pathology Day
- May 01, 2024
Yale Pathology Faculty Members Recognized as Top Doctors
- June 27, 2023
Yale Pathology Joins Office of Health Equity Research in Community Listening Session
- October 06, 2022
Natalia Buza, MD, Named First Director of New Yale Pathology Center of Excellence for Women’s Health
Get In Touch
Contacts
Administrative Support
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
Events
- EveryoneAndrea Barbieri, MD - Rita Abi-Raad, MDhttps://yale.zoom.us/j/99370751754 Meeting ID: 993 7075 1754 Or Telephone:203-432-9666 (2-ZOOM if on-campus) or 646 568 7788