Pramod Narayan Bonde, MD

Associate Professor of Surgery (Cardiac Surgery); Surgical Director of Mechanical Circulatory Support; Associate Program Director Cardiothoracic Surgery Residency Program

Research Interests

Biomedical Engineering; Heart Valves; Miniaturization; Medical Laboratory Science; Heart Transplantation; Minimally Invasive Surgical Procedures; Heart Valve Prosthesis Implantation; Biomedical Technology

Research Organizations

Surgery: Bonde Lab | Cardiac Surgery

Research Summary

The major focus of my research is understanding the mechanisms and processes involved in myocardial recovery supported by mechanical circulatory support. The treatment of heart failure currently is targeted towards minimizing the neurohumoral effects (diuretics, ACE inhibitors, beta blockers) of failing myocardium and as such is merely symptomatic without improving the underlying heart failure. Mechanical circulatory support can reverse the heart failure and can be an effective strategy to interrupt the relentless progression of heart failure. My vision constitutes a small intra-cardiac mechanical circulatory device, which can be inserted by minimally invasive surgery and can be powered wirelessly to offer an un-tethered and unrestricted quality of life. Such device will use a novel controller algorithm to train the myocardium to recover to its fullest extent, eventually to be weaned completely from mechanical support. For such a vision to crystallize it needs three essential components: a small innovative ventricular assist device (VAD), a wireless transmission system and a reproducible animal model of heart failure. My lab has focused on these areas to bring this to reality in the last few years.

Extensive Research Description

FREE-D wireless power system


Artificial heart

Artificial Lung(Pulmonary Assist device)


Myocardial recovery using LVAD as a bridge

Mechanical CPR devices

Percutaneous artificial heart valves

Instrumentation and devices for minimally invasive cardiac surgery

Wireless pacemaker/AICDs.

Outcomes research

Heart Tarnsplantation

Lung Transplantation

Selected Publications

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