In 2009, the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act) was passed which gave the U.S. Food and Drug Administration (FDA) the authority to regulate the manufacture, distribution, and marketing of tobacco products to protect public health. With the passage of the Tobacco Control Act, NIH and the FDA formed an interagency partnership to foster tobacco regulatory research. At the center of this association is the funding of 14 Tobacco Centers of Regulatory Science (TCORS), made up of scientists with a broad range of expertise develop science-based policies to reduce addiction to tobacco products.
The Yale Tobacco Center of Regulatory Science (TCORS) conducts programmatic research to examine the influence of flavors, and related factors, on preference for and addiction to tobacco products. With the overarching goal of reducing addiction to tobacco products, the Yale TCORS will conduct detailed evaluations of the influence of flavors and sweeteners on the addictive potential of tobacco products. Cohesive and hypothesis driven, our research incorporates multiple methods and disciplines. The multidisciplinary team includes experts in sensory perception, tobacco addiction, adolescent tobacco use, menthol and irritant receptor biology, nicotinic receptor biology, dopaminergic signaling in brain reward pathways, human behavioral pharmacology, assay and clinical pharmacokinetics of drugs of abuse, analytical chemistry, health economics and decision making science, and tobacco regulation.
In addition, the center trains scientists, and provides pilot funding to stimulate research related to tobacco regulatory science.