2024
Pre-COVID-19 hospital quality and hospital response to COVID-19: examining associations between risk-adjusted mortality for patients hospitalised with COVID-19 and pre-COVID-19 hospital quality
Peter D, Li S, Wang Y, Zhang J, Grady J, McDowell K, Norton E, Lin Z, Bernheim S, Venkatesh A, Fleisher L, Schreiber M, Suter L, Triche E. Pre-COVID-19 hospital quality and hospital response to COVID-19: examining associations between risk-adjusted mortality for patients hospitalised with COVID-19 and pre-COVID-19 hospital quality. BMJ Open 2024, 14: e077394. PMID: 38553067, PMCID: PMC10982775, DOI: 10.1136/bmjopen-2023-077394.Peer-Reviewed Original ResearchMeSH KeywordsAgedCOVID-19Hospital MortalityHospitalsHumansMedicarePandemicsRetrospective StudiesUnited StatesConceptsHospital qualityPatient experiencePre-COVID-19Medicare patientsShort-term acute care hospitalsCritical access hospitalsAcute care hospitalsFuture public health emergenciesHigher odds of mortalityIn-hospitalRisk-adjusted mortalityOdds of mortalityCare deliveryAccess hospitalsEffective careCOVID-19-related deathsAssociated with mortalityCare structuresHospital characteristicsPublic health emergencySummary scoreMedicare beneficiariesHigher oddsHospital responseRSMRs
2023
Racial Differences in Presentation and Outcomes After Peripheral Arterial Interventions: Insights From the NCDR-PVI Registry
Julien H, Wang Y, Curtis J, Johnston-Cox H, Eberly L, Wang G, Nathan A, Fanaroff A, Khatana S, Groeneveld P, Secemsky E, Eneanya N, Vora A, Kobayashi T, Barbery C, Chery G, Kohi M, Kirksey L, Armstrong E, Jaff M, Giri J. Racial Differences in Presentation and Outcomes After Peripheral Arterial Interventions: Insights From the NCDR-PVI Registry. Circulation Cardiovascular Interventions 2023, 16: e011485. PMID: 37339237, DOI: 10.1161/circinterventions.121.011485.Peer-Reviewed Original ResearchConceptsDistressed Communities Index scorePeripheral arterial interventionsBlack patientsDrug-eluting technologiesWhite patientsArterial interventionsIndex scoreAcute kidney injuryRate of amputationSocioeconomic statusMultivariable logistic regressionPatient's zip codeZip codesMedicaid Services dataLow socioeconomic statusHigh ratePVI procedureKidney injuryMajor amputationIntervention RegistryHigh prevalenceAmerican CollegePatientsRevascularizationLogistic regression
2012
Impact of Community Wealth on Use of Cardiac-Resynchronization Therapy With Defibrillators for Heart Failure Patients
Farmer S, Tuohy E, Small D, Wang Y, Groeneveld P. Impact of Community Wealth on Use of Cardiac-Resynchronization Therapy With Defibrillators for Heart Failure Patients. Circulation Cardiovascular Quality And Outcomes 2012, 5: 798-807. PMID: 23093561, DOI: 10.1161/circoutcomes.112.965509.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesChi-Square DistributionCommunity Health ServicesDefibrillators, ImplantableEconomics, HospitalElectric CountershockFemaleHealth Care CostsHealth Services AccessibilityHealthcare DisparitiesHeart FailureHumansIncomeLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioRegistriesResidence CharacteristicsRetrospective StudiesTreatment OutcomeUnited StatesConceptsCardiac resynchronization therapyHospital resourcesNational Cardiovascular Data RegistryHeart failure patientsHeart failure therapyPatient-level variablesMajor health policy concernFailure patientsFailure therapyInsurance statusHospital characteristicsPatient stayCardiovascular disease treatmentHealth policy concernData registryPatientsPatient volumeMedian household incomeHealth policyTherapyInsurance coverageSignificant predictorsDisease treatmentHospital ownershipAverage median household income
2011
US Cardiologist Workforce From 1995 To 2007: Modest Growth, Lasting Geographic Maldistribution Especially In Rural Areas
Aneja S, Ross JS, Wang Y, Matsumoto M, Rodgers GP, Bernheim SM, Rathore SS, Krumholz HM. US Cardiologist Workforce From 1995 To 2007: Modest Growth, Lasting Geographic Maldistribution Especially In Rural Areas. Health Affairs 2011, 30: 2301-2309. PMID: 22147857, PMCID: PMC3332098, DOI: 10.1377/hlthaff.2011.0255.Peer-Reviewed Original ResearchConceptsPrimary care physiciansCare physiciansGeographic maldistributionChronic cardiovascular diseaseHospital referral regionsUse of telemedicineCardiology workforceNumber of cardiologistsTotal physician workforceCardiovascular diseaseCardiovascular careReferral regionsElderly populationUS populationTotal physiciansCardiologistsPhysiciansAge sixtyPhysician workforceDisadvantaged areasPercentRural areasPopulationDiseaseVariety of strategiesInfluence of Age on Perioperative Complications Among Patients Undergoing Implantable Cardioverter-Defibrillators for Primary Prevention in the United States
Tsai V, Goldstein MK, Hsia HH, Wang Y, Curtis J, Heidenreich PA. Influence of Age on Perioperative Complications Among Patients Undergoing Implantable Cardioverter-Defibrillators for Primary Prevention in the United States. Circulation Cardiovascular Quality And Outcomes 2011, 4: 549-556. PMID: 21878667, DOI: 10.1161/circoutcomes.110.959205.Peer-Reviewed Original ResearchConceptsAdverse eventsICD RegistryPrimary prevention ICD recipientsEnd pointImplantable cardioverter defibrillator recipientsPatients 85 yearsPrimary prevention patientsMinor adverse eventsPrimary end pointSecondary end pointsMajor adverse eventsCongestive heart failureCoronary artery diseaseLength of stayInfluence of ageHospital mortalityICD trialsPerioperative complicationsPeriprocedural complicationsArtery diseaseHeart failureICD recipientsRenal diseaseIncreased oddsAtrial fibrillationAge Differences in Primary Prevention Implantable Cardioverter‐Defibrillator Use in U.S. Individuals
Tsai V, Goldstein MK, Hsia HH, Wang Y, Curtis J, Heidenreich PA, Registry O. Age Differences in Primary Prevention Implantable Cardioverter‐Defibrillator Use in U.S. Individuals. Journal Of The American Geriatrics Society 2011, 59: 1589-1595. PMID: 21883101, DOI: 10.1111/j.1532-5415.2011.03542.x.Peer-Reviewed Original ResearchConceptsICD RegistryICD useNonarrhythmic deathHigh riskImplantable cardioverter-defibrillator (ICD) useHigh comorbid burdenPrior myocardial infarctionRisk of deathHigh-risk individualsRisk stratification systemOlder U.S. adultsYounger age groupsComorbid burdenICD implantationEjection fractionICD recipientsPrimary preventionRetrospective studyMyocardial infarctionMortality riskLower riskAge groupsU.S. adultsYounger groupOlder adultsDual-Chamber Implantable Cardioverter-Defibrillator Selection Is Associated With Increased Complication Rates and Mortality Among Patients Enrolled in the NCDR Implantable Cardioverter-Defibrillator Registry
Dewland TA, Pellegrini CN, Wang Y, Marcus GM, Keung E, Varosy PD. Dual-Chamber Implantable Cardioverter-Defibrillator Selection Is Associated With Increased Complication Rates and Mortality Among Patients Enrolled in the NCDR Implantable Cardioverter-Defibrillator Registry. Journal Of The American College Of Cardiology 2011, 58: 1007-1013. PMID: 21867834, DOI: 10.1016/j.jacc.2011.04.039.Peer-Reviewed Original ResearchConceptsDual-chamber ICDHospital mortalityComplication rateDevice implantationDual-chamber implantable cardioverter-defibrillator (ICD) implantationNational Cardiovascular Data Registry ICD RegistryImplantable Cardioverter-Defibrillator RegistrySingle-chamber ICD implantationImplantable cardioverter defibrillator implantationHospital complication ratesSingle-chamber defibrillatorsCardioverter-defibrillator implantationMajority of patientsReal-world populationDual-chamber devicesSingle-chamber devicesLongitudinal cohort designMedical comorbiditiesPeriprocedural complicationsAdverse eventsBaseline characteristicsICD implantationICD indicationICD RegistryICD useUse of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study
Dorfman AL, Fazel R, Einstein AJ, Applegate KE, Krumholz HM, Wang Y, Christodoulou E, Chen J, Sanchez R, Nallamothu BK. Use of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study. JAMA Pediatrics 2011, 165: 458-464. PMID: 21199972, PMCID: PMC3686496, DOI: 10.1001/archpediatrics.2010.270.Peer-Reviewed Original ResearchConceptsDiagnostic imaging proceduresTomographic scanImaging proceduresRetrospective cohort analysisPopulation-based ratesPediatric populationPlain radiographyCohort analysisHigh dosesMedical diagnostic imaging proceduresStudy periodAppropriate useChildrenHigh rateMedical imaging proceduresScansFrequent useHealth care marketUS health care marketYearsPatientsInfantsPopulationCare marketUnitedHealthcareUnderstanding the use and impact of the online community in a national quality improvement campaign
Nembhard IM, Nazem AG, Webster TR, Wang Y, Krumholz HM, Bradley EH. Understanding the use and impact of the online community in a national quality improvement campaign. BMJ Quality & Safety 2011, 20: 68. PMID: 21228078, DOI: 10.1136/bmjqs.2010.040253.Peer-Reviewed Original ResearchConceptsOnline communitiesPerformance measurement issuesSilent usersNational Quality CampaignHeart attack careD2B AllianceMeasurement issuesQuality campaignOrganizationImprovement campaignInformation exchangeExpert guidanceRole changesQuality improvement campaignStaff useImpactHigh-volume usersAllianceCampaignPerformance improvementLack of associationData sourcesHospital SurveyHelpfulnessPerformance
2010
The performance of US hospitals as reflected in risk‐standardized 30‐day mortality and readmission rates for medicare beneficiaries with pneumonia
Lindenauer PK, Bernheim SM, Grady JN, Lin Z, Wang Y, Wang Y, Merrill AR, Han LF, Rapp MT, Drye EE, Normand S, Krumholz HM. The performance of US hospitals as reflected in risk‐standardized 30‐day mortality and readmission rates for medicare beneficiaries with pneumonia. Journal Of Hospital Medicine 2010, 5: e12-e18. PMID: 20665626, DOI: 10.1002/jhm.822.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesReadmission ratesHospital referral regionsReferral regionsMedicare beneficiariesMortality rateRisk-standardized readmission ratesNonfederal acute care hospitalsNational quality improvement effortsPattern of hospitalAcute care hospitalsCross-sectional studyService Medicare beneficiariesQuality improvement effortsMedian hospitalHospital dischargeElderly patientsHospital admissionCare hospitalReadmission analysisOutpatient MedicareLeading causePrincipal diagnosisPneumoniaPatients
2001
Blood Transfusion in Elderly Patients with Acute Myocardial Infarction
Wu W, Rathore S, Wang Y, Radford M, Krumholz H. Blood Transfusion in Elderly Patients with Acute Myocardial Infarction. New England Journal Of Medicine 2001, 345: 1230-1236. PMID: 11680442, DOI: 10.1056/nejmoa010615.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionBlood transfusionMyocardial infarctionElderly patientsHematocrit valuesMortality rateLower short-term mortality rateMedicare beneficiaries 65 yearsShort-term mortality rateUse of transfusionsCoronary artery diseaseBeneficiaries 65 yearsDegree of anemiaLow hematocrit valuesArtery diseaseRetrospective studySubgroup analysisTransfusionPatientsAdmissionInfarctionMortalityHematocritAdverse effectsAnemiaAcute myocardial infarction in the elderly: differences by age
Mehta R, Rathore S, Radford M, Wang Y, Wang Y, Krumholz H. Acute myocardial infarction in the elderly: differences by age. Journal Of The American College Of Cardiology 2001, 38: 736-741. PMID: 11527626, DOI: 10.1016/s0735-1097(01)01432-2.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overFemaleHumansMaleMyocardial InfarctionOdds RatioUnited StatesConceptsAcute myocardial infarctionAge-associated differencesElderly patientsClinical characteristicsAge groupsMyocardial infarctionThirty-day mortality rateMedicare beneficiaries ageOne-year mortalityPrior coronary diseaseProportion of patientsST-segment elevationOlder age groupsSignificant age-associated differencesChest painEffect of ageOlder patientsRenal insufficiencyCoronary diseaseHeart failureHospital admissionPatient characteristicsSuccessive age groupsSymptom onsetDiabetic patients
1999
Comparing AMI Mortality Among Hospitals in Patients 65 Years of Age and Older
Krumholz H, Chen J, Wang Y, Radford M, Chen Y, Marciniak T. Comparing AMI Mortality Among Hospitals in Patients 65 Years of Age and Older. Circulation 1999, 99: 2986-2992. PMID: 10368115, DOI: 10.1161/01.cir.99.23.2986.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionWhite blood cell countPatients 65 yearsSystolic blood pressureCongestive heart failureMedical chart reviewReceiver-operating characteristic curveBlood cell countRisk-adjusted outcomesYears of ageAdministrative billing codesRisk-adjustment modelsHospital outcomesSerum creatinineChart reviewDerivation cohortHeart failurePatient characteristicsBlood pressureCardiac arrestValidation cohortCandidate predictor variablesAMI mortalityBilling codes