2017
Differences in Prevalence of Symptomatic Zika Virus Infection, by Age and Sex—Puerto Rico, 2016
Lozier MJ, Burke RM, Lopez J, Acevedo V, Amador M, Read JS, Jara A, Waterman SH, Barrera R, Muñoz-Jordan J, Rivera-Garcia B, Sharp TM. Differences in Prevalence of Symptomatic Zika Virus Infection, by Age and Sex—Puerto Rico, 2016. The Journal Of Infectious Diseases 2017, 217: 1678-1689. PMID: 29216376, PMCID: PMC8849542, DOI: 10.1093/infdis/jix630.Peer-Reviewed Original ResearchConceptsZIKV infectionReverse transcription-polymerase chain reactionEnzyme-linked immunosorbent assaySex-dependent differencesSymptomatic infectionFemale sexSymptomatic Zika virus infectionZika virus infectionSymptomatic ZIKV infectionZika virus diseaseTranscription-polymerase chain reactionNonpregnant womenResidents of householdsZIKV diseaseRecent illnessVirus infectionDisease casesDiagnostic testingStudy participantsInfectionImmunosorbent assayConvenience samplePotential mechanismsChain reactionAgeAcute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico
Dirlikov E, Medina NA, Major CG, Munoz-Jordan JL, Luciano CA, Rivera-Garcia B, Sharp TM. Acute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico. JAMA 2017, 318: 1498-1500. PMID: 29049645, PMCID: PMC5817969, DOI: 10.1001/jama.2017.11483.Peer-Reviewed Original Research
2016
Use of Household Cluster Investigations to Identify Factors Associated with Chikungunya Virus Infection and Frequency of Case Reporting in Puerto Rico
Bloch D, Roth NM, Caraballo EV, Muñoz-Jordan J, Hunsperger E, Rivera A, Pérez-Padilla J, Garcia B, Sharp TM. Use of Household Cluster Investigations to Identify Factors Associated with Chikungunya Virus Infection and Frequency of Case Reporting in Puerto Rico. PLOS Neglected Tropical Diseases 2016, 10: e0005075. PMID: 27764085, PMCID: PMC5072658, DOI: 10.1371/journal.pntd.0005075.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAgedAged, 80 and overAir ConditioningAntibodies, ViralChikungunya FeverChikungunya virusChildChild, PreschoolCymbopogonDisease NotificationDisease OutbreaksEnzyme-Linked Immunosorbent AssayExanthemaFamily CharacteristicsFemaleFeverHumansInfantMaleMiddle AgedPoint-of-Care SystemsPolymerase Chain ReactionPuerto RicoYoung AdultConceptsSymptomatic CHIKV infectionRecent CHIKV infectionCHIKV infectionPublic health authoritiesChikungunya virusChikungunya patientsMedical careHealth authoritiesCase reportingAnti-CHIKV IgMAcute febrile illnessChikungunya virus infectionCare rapid diagnostic testsRapid diagnostic testsPuerto Rico DepartmentCluster investigationsAcute illnessFebrile illnessSkin rashResidents of householdsDevelopment of diseaseMultivariable analysisIllness onsetIgG antibodiesIgM ELISAEarly Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico
Sharp TM, García B, Pérez-Padilla J, Galloway RL, Guerra M, Ryff KR, Haberling D, Ramakrishnan S, Shadomy S, Blau D, Tomashek KM, Bower WA. Early Indicators of Fatal Leptospirosis during the 2010 Epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2016, 10: e0004482. PMID: 26914210, PMCID: PMC4767218, DOI: 10.1371/journal.pntd.0004482.Peer-Reviewed Original ResearchConceptsFirst medical visitWhite blood cellsLeptospirosis patientsFatal outcomeMedical visitsFatal leptospirosisLaboratory valuesHospitalized leptospirosis patientsNon-fatal patientsRoutine laboratory valuesLeg painControl patientsMost patientsCase patientsHospital admissionMultivariable analysisIllness onsetPlatelet countDengue patientsFatal casesWBC countLeptospirosis epidemicPatientsMedical careOld male