Virus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico
Sharp TM, Hunsperger E, Santiago GA, Muñoz-Jordan JL, Santiago LM, Rivera A, Rodríguez-Acosta RL, Feliciano L, Margolis HS, Tomashek KM. Virus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2013, 7: e2159. PMID: 23593526, PMCID: PMC3617145, DOI: 10.1371/journal.pntd.0002159.Peer-Reviewed Original ResearchConceptsAcute febrile illnessReverse transcriptase-polymerase chain reactionLaboratory-positive casesPrimary infectionDengue casesDENV-1DENV-2Anti-DENV IgM antibodiesSerum specimenMortality of dengueMosquito-transmitted dengue virusPrimary DENV infectionPassive dengue surveillance systemHealth care providersPrimary prevention interventionsTranscriptase-polymerase chain reactionOnly age groupDENV nucleic acidLaboratory diagnostic dataRates of diseaseFebrile illnessSevere dengueDENV infectionIgM antibodiesDENV antigen