2024
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancy
2023
Mendelian randomization study of birthweight, gestational age, and risk of childhood acute lymphoblastic leukemia
Rogne T, DeWan A, Metayer C, Wiemels J, Ma X. Mendelian randomization study of birthweight, gestational age, and risk of childhood acute lymphoblastic leukemia. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101058. PMID: 37330008, DOI: 10.1016/j.ajogmf.2023.101058.Peer-Reviewed Original ResearchDyslipidemia and Risk of Preeclampsia: A Multiancestry Mendelian Randomization Study
Hosier H, Lipkind H, Rasheed H, DeWan A, Rogne T. Dyslipidemia and Risk of Preeclampsia: A Multiancestry Mendelian Randomization Study. Hypertension 2023, 80: 1067-1076. PMID: 36883459, DOI: 10.1161/hypertensionaha.122.20426.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaProtective effectCholesteryl Ester Transfer Protein InhibitionLack of effectMendelian randomization studyMendelian randomization analysisMaternal morbidityElevated HDLLeading causeLipid levelsObservational studyPreeclampsiaLipid measurementsReduced riskAncestry groupsPharmacological targetsRandomization studyHDLLDLRandomization analysisSingle nucleotide polymorphismsNew targetsDyslipidemiaRiskProtein inhibitionSex‐Specific Reproductive Factors Augment Cardiovascular Disease Risk in Women: A Mendelian Randomization Study
Ardissino M, Slob E, Carter P, Rogne T, Girling J, Burgess S, Ng F. Sex‐Specific Reproductive Factors Augment Cardiovascular Disease Risk in Women: A Mendelian Randomization Study. Journal Of The American Heart Association 2023, 12: e027933. PMID: 36846989, PMCID: PMC10111460, DOI: 10.1161/jaha.122.027933.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseBody mass indexHeart failureCardiovascular diseaseReproductive factorsArtery diseaseIschemic strokeMass indexAtrial fibrillationLive birthsFirst birthCardiovascular disease riskType 2 diabetesBackground Observational studiesMendelian randomizationMendelian randomization studyModifiable mediatorsBlood pressureResidual confoundingObservational studyPrimary analysisRandomization studyDisease riskStrokeClinical interventionsOutdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers
Zhong C, Wang R, Morimoto L, Longcore T, Franklin M, Rogne T, Metayer C, Wiemels J, Ma X. Outdoor artificial light at night, air pollution, and risk of childhood acute lymphoblastic leukemia in the California Linkage Study of Early-Onset Cancers. Scientific Reports 2023, 13: 583. PMID: 36631468, PMCID: PMC9834257, DOI: 10.1038/s41598-022-23682-z.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaRisk of childhoodEarly-onset cancersLymphoblastic leukemiaBirth recordsChildhood acute lymphoblastic leukemiaNon-Hispanic white childrenHispanic childrenCalifornia Cancer RegistryEtiology of childhoodOutdoor artificial lightOutdoor ALANHighest tertileCancer RegistryLinkage studiesRisk factorsBorderline associationElevated riskCancer diagnosisCancerEnvironmental exposuresWhite childrenCommon typeAir pollutionRisk
2022
Insomnia symptoms and risk of bloodstream infections: prospective data from the prospective population‐based Nord‐Trøndelag Health Study (HUNT), Norway
Thorkildsen MS, Laugsand LE, Nilsen TIL, Mohus RM, Høvik LH, Rogne T, Solligård E, Damås JK, Gustad LT. Insomnia symptoms and risk of bloodstream infections: prospective data from the prospective population‐based Nord‐Trøndelag Health Study (HUNT), Norway. Journal Of Sleep Research 2022, 32: e13696. PMID: 36068650, PMCID: PMC10078600, DOI: 10.1111/jsr.13696.Peer-Reviewed Original ResearchMeSH KeywordsHumansNorwayProspective StudiesRisk FactorsSepsisSleep Initiation and Maintenance DisordersConceptsFirst-time bloodstream infectionNord-Trøndelag Health StudyHazard ratioBloodstream infectionsInsomnia symptomsProspective dataHealth StudyConfidence intervalsNorwegian Nord-Trøndelag Health StudyRisk of BSIPopulation-based prospective studyPopulation-based Nord-Trøndelag Health StudyFrequent insomnia symptomsNon-restorative sleepRisk of infectionCox regressionProspective studyAbove symptomsImmune functionSymptomsInfectionMortalitySleepRiskParticipantsExplaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway
Mohus RM, Gustad LT, Furberg AS, Moen MK, Liyanarachi KV, Askim Å, Åsberg SE, DeWan AT, Rogne T, Simonsen GS, Nilsen TIL, Åsvold BO, Damås JK, Solligård E. Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway. Scientific Reports 2022, 12: 8436. PMID: 35589812, PMCID: PMC9118181, DOI: 10.1038/s41598-022-12569-8.Peer-Reviewed Original ResearchConceptsIncident bloodstream infectionCardiovascular risk factorsBloodstream infectionsBSI mortalityRisk factorsHigh riskHealth behaviorsFirst-time bloodstream infectionRisk of BSIPotential modifiable risk factorsPopulation-based HUNT StudyModifiable risk factorsSex differencesHospital recordsProspective studyHUNT StudyExcess riskMediation analysisCausal mediation analysisEffects of sexMortalityComorbiditiesWomenMenRiskModifiable risk factors for ectopic pregnancy: a Mendelian randomization study
Rogne T, Liew Z, Hernáez Á, Brumpton BM, Magnus MC. Modifiable risk factors for ectopic pregnancy: a Mendelian randomization study. American Journal Of Obstetrics And Gynecology 2022, 227: 339-341.e4. PMID: 35390318, DOI: 10.1016/j.ajog.2022.03.063.Peer-Reviewed Original Research
2021
Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway
Grønseth S, Rogne T, Hannula R, Åsvold BO, Afset JE, Damås JK. Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway. BMC Infectious Diseases 2021, 21: 659. PMID: 34233631, PMCID: PMC8262122, DOI: 10.1186/s12879-021-06144-1.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusRegional incidence ratesRetrospective studyMedical recordsIncidence rateP. jiroveciiTwelve-year retrospective studyMain clinical findingsMajor risk factorPatients' medical recordsHospital mortalityImmunosuppressant usePCP prophylaxisClinical characteristicsMost patientsRadiological featuresPerson yearsClinical findingsImmunodeficiency virusIntensive carePolymerase chain reactionRisk factorsModern chemotherapyCardinal symptomsStudy populationGWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections
Rogne T, Liyanarachi KV, Rasheed H, Thomas LF, Flatby HM, Stenvik J, Løset M, Gill D, Burgess S, Willer CJ, Hveem K, Åsvold BO, Brumpton BM, DeWan AT, Solligård E, Damås JK. GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections. Journal Of Investigative Dermatology 2021, 141: 2083-2086.e8. PMID: 33662382, PMCID: PMC7612997, DOI: 10.1016/j.jid.2021.01.020.Peer-Reviewed Original Research
2020
Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study
Rogne T, Solligård E, Burgess S, Brumpton BM, Paulsen J, Prescott HC, Mohus RM, Gustad LT, Mehl A, Åsvold BO, DeWan AT, Damås JK. Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study. PLOS Medicine 2020, 17: e1003413. PMID: 33196656, PMCID: PMC7668585, DOI: 10.1371/journal.pmed.1003413.Peer-Reviewed Original ResearchConceptsBody mass indexHigher body mass indexBloodstream infectionsBSI incidenceBSI mortalityHazard ratioMass indexGeneral populationPopulation-based cohortAnalysis of patientsTerms of mortalityMendelian randomization studyTraditional epidemiological studiesMendelian randomization analysisObesity paradoxMean ageObservational studyEpidemiological studiesRandomization studyCausal associationSepsisMortalityPatientsInfectionRandomization analysisCardiometabolic Traits, Sepsis, and Severe COVID-19
Ponsford MJ, Gkatzionis A, Walker VM, Grant AJ, Wootton RE, Moore LSP, Fatumo S, Mason AM, Zuber V, Willer C, Rasheed H, Brumpton B, Hveem K, Damås J, Davies N, Åsvold BO, Solligård E, Jones S, Burgess S, Rogne T, Gill D. Cardiometabolic Traits, Sepsis, and Severe COVID-19. Circulation 2020, 142: 1791-1793. PMID: 32966752, PMCID: PMC7594537, DOI: 10.1161/circulationaha.120.050753.Peer-Reviewed Original ResearchBetacoronavirusBody Mass IndexCase-Control StudiesCoronavirus InfectionsCOVID-19Diabetes Mellitus, Type 2DyslipidemiasGene-Environment InteractionGenetic Association StudiesGenetic Predisposition to DiseaseHost-Pathogen InteractionsHumansMendelian Randomization AnalysisObesityPandemicsPhenotypePneumonia, ViralPolymorphism, Single NucleotideRisk FactorsSARS-CoV-2SepsisSeverity of Illness IndexSmokingGenome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study).
Rogne T, Damås JK, Solligård E, DeWan AT. Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study). Critical Care Medicine 2020, 48: 1580-1586. PMID: 32885941, DOI: 10.1097/ccm.0000000000004520.Peer-Reviewed Original ResearchThe Role of FER rs4957796 in the Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-up of the Population-based Nord-Trøndelag Health Study
Rogne T, Damås JK, Flatby HM, Åsvold BO, DeWan AT, Solligård E. The Role of FER rs4957796 in the Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-up of the Population-based Nord-Trøndelag Health Study. Clinical Infectious Diseases 2020, 73: e297-e303. PMID: 32699877, PMCID: PMC8282309, DOI: 10.1093/cid/ciaa786.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaFollow-Up StudiesHumansProportional Hazards ModelsProspective StudiesRisk FactorsSepsisConceptsBloodstream infectionsHUNT StudyCC genotypePopulation-based HUNT StudyBloodstream infection incidenceBloodstream infection patientsTotal study populationTerms of mortalityInfection patientsSepsis mortalityCase fatalityImmunoregulatory roleDiagnosis codesProspective dataStudy populationTT genotypeBlood samplesInfection incidencePatientsC alleleInfectionMajor causeHealth lossMortalitySingle nucleotide polymorphisms
2017
Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data
Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L, Jaddoe VW, Steegers EA, Joshi S, Chong YS, Godfrey KM, Yap F, Yahyaoui R, Thomas T, Hay G, Hogeveen M, Demir A, Saravanan P, Skovlund E, Martinussen MP, Jacobsen GW, Franco OH, Bracken MB, Risnes KR. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. American Journal Of Epidemiology 2017, 185: 212-223. PMID: 28108470, PMCID: PMC5390862, DOI: 10.1093/aje/kww212.Peer-Reviewed Original ResearchConceptsLow birth weightPreterm birthBirth weightB12 deficiencyIndividual participant dataB12 concentrationsHigh riskSystematic reviewParticipant dataMaternal B12 levelsLinear associationVitamin B12 supplementationVitamin B12 deficiencyOffspring birth weightVitamin B12 concentrationsLength of gestationB12 levelsB12 supplementationMaternal serumMaternal levelsEligible studiesCurrent evidencePregnancyMeta-AnalysisBirth
2014
Association between low blood glucose increase during glucose tolerance tests in pregnancy and impaired fetal growth
Rogne T, Jacobsen GW. Association between low blood glucose increase during glucose tolerance tests in pregnancy and impaired fetal growth. Acta Obstetricia Et Gynecologica Scandinavica 2014, 93: 1160-1169. PMID: 24576054, DOI: 10.1111/aogs.12365.Peer-Reviewed Original ResearchConceptsGlucose tolerance testFetal growthFetal weightTolerance testGlucose challengeWeek 25Oral glucose tolerance testMaternal blood glucoseLow groupProspective cohort studyGestational week 25Low-risk populationOral glucose challengeHigh-risk populationBlood glucose increaseCapillary glucose valuesPoisson regression modelsLighter babiesCohort studyPregnant womenBlood glucoseLate pregnancyLight fetusesWeek 37Anthropometric measures