2024
A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections
Flatby H, Ravi A, Liyanarachi K, Afset J, Rasheed H, Brumpton B, Hveem K, Åsvold B, DeWan A, Solligård E, Damås J, Rogne T. A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. The Journal Of Infectious Diseases 2024, jiae231. PMID: 38713594, DOI: 10.1093/infdis/jiae231.Peer-Reviewed Original ResearchGenome-wide association studiesMichigan Genomics InitiativeAssociation studiesUpper UTIMendelian randomizationMR analysisUpper urinary tract infectionRisk factorsPotential causal risk factorsCardiometabolic risk factorsModifiable risk factorsSex-stratified analysesCausal risk factorUrinary tract infectionGenome-wideFemale-only analysisGenetic lociPotential causal relationshipGenome InitiativeHealth StudyUK BiobankHLA-DQA2LociTract infectionsSmoking score
2022
Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway
Mohus RM, Gustad LT, Furberg AS, Moen MK, Liyanarachi KV, Askim Å, Åsberg SE, DeWan AT, Rogne T, Simonsen GS, Nilsen TIL, Åsvold BO, Damås JK, Solligård E. Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway. Scientific Reports 2022, 12: 8436. PMID: 35589812, PMCID: PMC9118181, DOI: 10.1038/s41598-022-12569-8.Peer-Reviewed Original ResearchConceptsIncident bloodstream infectionCardiovascular risk factorsBloodstream infectionsBSI mortalityRisk factorsHigh riskHealth behaviorsFirst-time bloodstream infectionRisk of BSIPotential modifiable risk factorsPopulation-based HUNT StudyModifiable risk factorsSex differencesHospital recordsProspective studyHUNT StudyExcess riskMediation analysisCausal mediation analysisEffects of sexMortalityComorbiditiesWomenMenRisk