2023
Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis
Lawler P, Manvelian G, Coppi A, Damask A, Cantor M, Ferreira M, Paulding C, Banerjee N, Li D, Jorgensen S, Attre R, Carey D, Krebs K, Milani L, Hveem K, Damås J, Solligård E, Stender S, Tybjærg-Hansen A, Nordestgaard B, Hernandez-Beeftink T, Rogne T, Flores C, Villar J, Walley K, Liu V, Fohner A, Lotta L, Kyratsous C, Sleeman M, Scemama M, DelGizzi R, Pordy R, Horowitz J, Baras A, Martin G, Steg P, Schwartz G, Szarek M, Goodman S. Pharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis. Critical Care Explorations 2023, 5: e0997. PMID: 37954898, PMCID: PMC10635596, DOI: 10.1097/cce.0000000000000997.Peer-Reviewed Original ResearchProprotein convertase subtilisin/kexin type 9Convertase subtilisin/kexin type 9Subtilisin/kexin type 9Human cohort studiesODYSSEY OUTCOMESCohort studyType 9Isotype-matched controlExperimental murine modelSepsis ratePCSK9 inhibitionPCSK9 inhibitorsSepsis complicationsSepsis mortalitySepsis outcomeImproved survivalBacterial sepsisClinical outcomesBloodstream clearanceSepsis modelClinical trialsOdds ratioCardiovascular diseasePretreatment settingSepsis diagnosis
2017
Longitudinal Ultrasound Measures of Fetal Growth and Offspring Outcomes
Larose T, Turner S, Hutcheon J, Rogne T, Riphagen I, Martinussen M, Jacobsen G. Longitudinal Ultrasound Measures of Fetal Growth and Offspring Outcomes. Current Epidemiology Reports 2017, 4: 98-105. DOI: 10.1007/s40471-017-0103-2.Peer-Reviewed Original ResearchFetal growth restrictionFetal growthGrowth restrictionOffspring outcomesLongitudinal ultrasonographyAdverse clinical outcomesNon-communicable diseasesLongitudinal ultrasound measurementsPurpose of ReviewInLong-term healthClinical outcomesGestational ageSmall fetusesPerinatal periodDisease outcomePredictive valueUltrasonographyNarrative reviewPostnatal growthUltrasound measuresUltrasound measurementsRecent evidenceOutcomesSame individualPregnancy