2021
La Crosse Virus Shows Strain-Specific Differences in Pathogenesis
Wilson S, López K, Coutermash-Ott S, Auguste D, Porier D, Armstrong P, Andreadis T, Eastwood G, Auguste A. La Crosse Virus Shows Strain-Specific Differences in Pathogenesis. Pathogens 2021, 10: 400. PMID: 33805389, PMCID: PMC8066585, DOI: 10.3390/pathogens10040400.Peer-Reviewed Original ResearchLa Crosse virusPediatric viral encephalitisNeuroinvasive capacityPublic health pathogenViral encephalitisImportant public health pathogenMurine modelEndemic regionsStrain-specific differencesTherapeutic efficacyExcessive mortalityPathogenesisViral strainsMouse studiesVirusNeurovirulenceMortalityContemporaneous strainsLineage IEntomological riskEncephalitisVaccineDisease
1992
Infectivity and pathogenesis of iridescent virus type 22 in various insect hosts
Tesh R, Andreadis T. Infectivity and pathogenesis of iridescent virus type 22 in various insect hosts. Archives Of Virology 1992, 126: 57-65. PMID: 1355961, DOI: 10.1007/bf01309684.Peer-Reviewed Original ResearchConceptsType 22Day observation periodViral antigensInfected mosquitoesVirus replicationObservation periodTransovarial transmissionPathogenesisDifferent organsVirus particlesHost cell cytoplasmSmall percentageSand fliesSpecies of mosquitoesInfectivityMidgut epitheliumMosquitoesPhlebotomine sand fliesCell cytoplasmFat bodyMortalityTrachealAntigenInfected insectsEpithelium