2021
La Crosse Virus Shows Strain-Specific Differences in Pathogenesis
Wilson S, López K, Coutermash-Ott S, Auguste D, Porier D, Armstrong P, Andreadis T, Eastwood G, Auguste A. La Crosse Virus Shows Strain-Specific Differences in Pathogenesis. Pathogens 2021, 10: 400. PMID: 33805389, PMCID: PMC8066585, DOI: 10.3390/pathogens10040400.Peer-Reviewed Original ResearchLa Crosse virusPediatric viral encephalitisNeuroinvasive capacityPublic health pathogenViral encephalitisImportant public health pathogenMurine modelEndemic regionsStrain-specific differencesTherapeutic efficacyExcessive mortalityPathogenesisViral strainsMouse studiesVirusNeurovirulenceMortalityContemporaneous strainsLineage IEntomological riskEncephalitisVaccineDisease
2020
Local persistence of novel regional variants of La Crosse virus in the Northeast USA
Eastwood G, Shepard J, Misencik M, Andreadis T, Armstrong P. Local persistence of novel regional variants of La Crosse virus in the Northeast USA. Parasites & Vectors 2020, 13: 569. PMID: 33176861, PMCID: PMC7659055, DOI: 10.1186/s13071-020-04440-4.Peer-Reviewed Original ResearchConceptsHuman casesMosquito-borne virusLa Crosse virusPediatric encephalitisField-collected mosquitoesLACV infectionConclusionOur analysisLocal mosquito populationsVirusPublic healthVirus lineagesLACVNew York StateMosquito populationsMosquitoesEncephalitisIsolatesLong-term persistenceInfectionPrevalenceCases