2024
Family history of psychiatric conditions and development of siblings of children with autism
Bellia G, Chang J, Liew Z, Vernetti A, Macari S, Powell K, Chawarska K. Family history of psychiatric conditions and development of siblings of children with autism. Autism Research 2024, 17: 1665-1676. PMID: 38896553, PMCID: PMC11341253, DOI: 10.1002/aur.3175.Peer-Reviewed Original ResearchSiblings of childrenNeuropsychiatric disordersFamilies of childrenFamily history of schizophreniaYounger siblings of childrenHistory of psychiatric conditionsHistory of schizophreniaYounger siblingsAssess autism symptomsNonverbal IQAutism symptomsBipolar disorderIntellectual disabilityPsychiatric conditionsSubclinical symptomsAdaptive skillsSocial affectAdaptive functioningAutismFamily historyParent interviewsFamily factorsMultiple regression analysisDevelopmental outcomesDisorders
2016
Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study
Charman T, Young GS, Brian J, Carter A, Carver LJ, Chawarska K, Curtin S, Dobkins K, Elsabbagh M, Georgiades S, Hertz‐Picciotto I, Hutman T, Iverson JM, Jones EJ, Landa R, Macari S, Messinger DS, Nelson CA, Ozonoff S, Saulnier C, Stone WL, Tager‐Flusberg H, Webb SJ, Yirmiya N, Zwaigenbaum L. Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study. Autism Research 2016, 10: 169-178. PMID: 27417857, PMCID: PMC5993543, DOI: 10.1002/aur.1669.Peer-Reviewed Original ResearchConceptsAutism Diagnostic Observation ScheduleAutism spectrum disorderHigh-risk siblingsLow-risk controlsBroader autism phenotypeModerate language delayAdaptive functioningASD symptomsLanguage delayVineland Adaptive Behavior ScalesLower adaptive functioningAge 3 yearsAutism Diagnostic InterviewProportion of toddlersAdaptive behavior outcomesAdaptive Behavior ScalesOngoing clinical monitoringAutism phenotypeMullen ScalesSpectrum disorderObservation ScheduleEarly learningBehavioral outcomesElevated scoresDevelopmental outcomes
2014
18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study
Chawarska K, Shic F, Macari S, Campbell DJ, Brian J, Landa R, Hutman T, Nelson CA, Ozonoff S, Tager-Flusberg H, Young GS, Zwaigenbaum L, Cohen IL, Charman T, Messinger DS, Klin A, Johnson S, Bryson S. 18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 1317-1327.e1. PMID: 25457930, PMCID: PMC4254798, DOI: 10.1016/j.jaac.2014.09.015.Peer-Reviewed Original ResearchConceptsPoor eye contactHigh riskEarly diagnostic considerationAutism spectrum disorderAge 3 yearsEye contactBaby Siblings Research Consortium StudyClinical featuresDiagnostic considerationsSpectrum disorderSpecific treatmentYounger siblingsSymptom profilesAutism Diagnostic Observation ScheduleConsortium studyMonthsDiagnostic outcomesRegression tree analysisOutcomesLater OutcomesChildrenDevelopmental outcomesHigh functioningSiblingsBehavioral profileScreening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report
Rowberry J, Macari S, Chen G, Campbell D, Leventhal JM, Weitzman C, Chawarska K. Screening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report. Journal Of Autism And Developmental Disorders 2014, 45: 221-229. PMID: 25149178, PMCID: PMC4289092, DOI: 10.1007/s10803-014-2211-x.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderParental reportsSpectrum disorderDevelopmental outcomesHigh-risk siblingsFirst Year InventoryVocal imitationRepetitive behaviorsSocial communicationGreater impairmentClinician ratingsYounger siblingsScreening instrumentPreliminary findingsASD casesImportant implicationsDisordersSiblingsImitationParentsRatingsImpairmentInventoryChildrenCommunication