2024
Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. PMID: 38504849, PMCID: PMC10948970, DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referral
2023
Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Out-of-Pocket Expenditure for Antenatal Care Amid Free Health Care Provision: Evidence From a Large Pregnancy Cohort in Rural Sri Lanka. Global Health Science And Practice 2023, 11: e2200410. PMID: 37903576, PMCID: PMC10615247, DOI: 10.9745/ghsp-d-22-00410.Peer-Reviewed Original ResearchConceptsMean OOP expenditureAntenatal careLarge pregnancy cohortPrivate health facilitiesPregnant womenHealth facilitiesOOP expenditureMaternal morbidityIndependent predictorsPrevious pregnancyPregnancy cohortHealth service utilizationInterviewer-administered questionnaireSignificant independent predictorsGovernment health facilitiesGovernment health servicesCare modeLaboratory investigationsHealth care usersSelf-administered questionnaireSri Lankan settingMonthly household incomeHealth care provisionANC visitsThird trimesterIncorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka
Agampodi T, Amarasinghe G, Wickramasinghe A, Wickramasinghe N, Warnasekara J, Jayasinghe I, Hettiarachchi A, Nimesha D, Dilshani T, Senadheera S, Agampodi S. Incorporating early pregnancy mental health screening and management into routine maternal care: experience from the Rajarata Pregnancy Cohort (RaPCo), Sri Lanka. BMJ Global Health 2023, 8: e012852. PMID: 37748792, PMCID: PMC10533714, DOI: 10.1136/bmjgh-2023-012852.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleMental health screeningMental health problemsPregnancy cohortSecond trimesterEarly pregnancyHealth screeningClinical InterviewHealth problemsPregnancy care programsRoutine maternal careTertiary care hospitalMental health service provisionPrimary healthcare levelHigher EPDS scoresPostnatal Depression ScaleWeeks of periodPregnancy-associated conditionsMental health gapPatient-centered careHealth service provisionHealth surveillance systemsCare hospitalMiddle-income countriesPregnant womenPeriod poverty in rural Sri Lanka; Understanding menstruation hygiene and related health issues to empower women.
Hettiarachchi A, Agampodi T, Agampodi S. Period poverty in rural Sri Lanka; Understanding menstruation hygiene and related health issues to empower women. Anuradhapura Medical Journal 2023, 17: 25-28. DOI: 10.4038/amj.v17i2.7759.Peer-Reviewed Original ResearchBlood lossManagement of menstruationComprehensive reproductive health educationMenstrual blood lossCross-sectional studyFinancial burdenHealth-seeking behaviourHygiene productsReproductive health educationMenstrual hygiene productsMoor ethnicityMenstrual historyPregnant womenRelated health issuesMenstrual issuesMenstruation hygieneMOH areaHealth educationRural Sri LankaMedical careLower educationHealth issuesImpact of COVID-19 pandemic on health service utilisation and household economy of pregnant and postpartum women: a cross-sectional study from rural Sri Lanka
Gunarathna S, Wickramasinghe N, Agampodi T, Prasanna I, Agampodi S. Impact of COVID-19 pandemic on health service utilisation and household economy of pregnant and postpartum women: a cross-sectional study from rural Sri Lanka. BMJ Open 2023, 13: e070214. PMID: 37247958, PMCID: PMC10230333, DOI: 10.1136/bmjopen-2022-070214.Peer-Reviewed Original ResearchConceptsCurrent economic crisisHousehold economyFree public health servicesFinancial assistanceNon-parametric analysisEconomic crisisEconomic dataMonthly household incomeSri LankaHealth service utilisationHousehold incomeEconomic componentCOVID-19 pandemicEconomyPovertyIncomeService utilisationRural Sri LankaPostpartum womenCross-sectional studyPregnant womenAnuradhapura districtPublic health servicesLankaHealthcare utilisationCohort Profile: The Rajarata Pregnancy Cohort (RaPCo)
Agampodi S, Wickramasinghe N, Agampodi T. Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo). Anuradhapura Medical Journal 2023, 17: 31. DOI: 10.4038/amj.v17i1.7757.Peer-Reviewed Original ResearchMaternal morbidityFirst trimesterPregnancy cohortPregnant womenFirst antenatal clinic visitEarly pregnancy miscarriageFatty liver gradePregnancy care programsFatty liver indexGestational age neonatesAntenatal clinic visitPregnancy outcome dataAnemic pregnant womenSignificant risk factorsComprehensive mental healthBaseline data collectionGestational diabetesAge neonatesClinic visitsCohort womenMetabolic syndromeMetabolic derangementsEarly pregnancyEntire cohortLiver indexEarly pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitionsSerum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy
Agampodi S, Agampodi T, Amarasinghe G, Warnasekara J, Hettiarachchi A, Jayasinghe I, Koralegedara I, Abeyrathna P, Srimantha S, de Silva F, Gunarathne S, Wickramasinghe N. Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy. PLOS Global Public Health 2023, 3: e0000443. PMID: 36962935, PMCID: PMC10021427, DOI: 10.1371/journal.pgph.0000443.Peer-Reviewed Original ResearchGlomerular filtration rateWeeks of gestationRenal functionPregnant womenNonpregnant womenSerum creatinineSecond trimesterEarly pregnancyFiltration rateClinical practiceCommunity-based prospective cohort studyProspective population-based studyPre-existing medical conditionsProspective cohort studyHealthy pregnant womenCommunity-based cohortPopulation-based studyDifferent age strataMean eGFRCohort studyNewborn outcomesNonpregnant groupPregnancy cohortFirst trimesterMean SCrDeterminants of birthweight in rural Sri Lanka; a cohort study
Banda P, Amarasinghe G, Agampodi S. Determinants of birthweight in rural Sri Lanka; a cohort study. BMC Pediatrics 2023, 23: 40. PMID: 36690991, PMCID: PMC9869565, DOI: 10.1186/s12887-022-03830-0.Peer-Reviewed Original ResearchConceptsMother-infant cohortPregnant womenCohort studyPreterm birthPsychosocial wellbeingThird trimester pregnant womenPerinatal health issuesProspective cohort studySocioeconomic statusPrimary care levelMaternal care servicesAntenatal care programsHusband's education levelSelf-completed questionnaireMiddle-income settingsEducation levelHierarchical logistic regressionPregnancy registrationHypertensive disordersMaternal BMISingleton pregnanciesThird trimesterBaby's sexChronic diabetesPerinatal health
2022
The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. The geo-spatial perspective of biological, social and environmental determinants of early pregnancy anaemia in rural Sri Lanka: Need for context-specific approaches on prevention. Geospatial Health 2022, 17 PMID: 36468596, DOI: 10.4081/gh.2022.1110.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaEarly pregnancyPregnant womenRisk factorsFirst trimester pregnant womenHigher anemia prevalenceAntenatal care programsEnvironmental risk factorsHeterogeneous risk factorsMaternal anemiaPregnancy anemiaPregnancy cohortAnemia prevalenceDietary patternsHigh prevalenceAnemiaCare programRural Sri LankaPrevalenceSocioeconomic disparitiesPregnancyHealth DivisionEthnic distributionSignificant differencesAnuradhapura districtFactors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities?
Amarasinghe G, Agampodi T, Mendis V, Agampodi S. Factors associated with early pregnancy anemia in rural Sri Lanka: Does being ‘under care’ iron out socioeconomic disparities? PLOS ONE 2022, 17: e0274642. PMID: 36201463, PMCID: PMC9536542, DOI: 10.1371/journal.pone.0274642.Peer-Reviewed Original ResearchConceptsPregnancy anemiaPregnant womenFirst trimester pregnant womenSocioeconomic disparitiesRisk of anemiaOdds of anemiaFull blood countHistory of anemiaContinuum of carePeriod of gestationFamily Health ProgramHierarchical logistic regression modelsSelf-completed questionnaireLogistic regression modelsHealth care coveragePublic health infrastructureMaternal anemiaAntenatal careCohort studyBreast feedingContraceptive injectionMiddle-income countriesAnemia preventionRegression modelsAnemia controlHelp-seeking intention for depression and suicidal ideation during pregnancy and postpartum in rural Sri Lanka, a cross-sectional study
Amarasinghe GS, Agampodi SB. Help-seeking intention for depression and suicidal ideation during pregnancy and postpartum in rural Sri Lanka, a cross-sectional study. Rural And Remote Health 2022, 22: 7273. PMID: 36059212, DOI: 10.22605/rrh7273.Peer-Reviewed Original ResearchConceptsSymptoms of depressionPublic health midwivesCross-sectional studyPregnant womenSuicidal ideationSuicidal thoughtsRural Sri LankaMental illnessHelp-seeking patternsHelp-seeking intentionsCommon mental illnessResource-constrained settingsMental health professionalsMaternal morbidityAntenatal clinicCurrent pregnancyMaternal deathsNumerous morbiditiesPeripartum depressionPostpartum mothersPostpartum periodMaternal depressionVignette-based questionnaireRisk populationsHealth professionalsAsthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period
Rajapakse S, Wickramasinghe N, Warnasekara J, Abeyrathna P, Amarasinghe G, Hettiarachchi AU, Jayasinghe IU, Koralegedara I, Agampodi TC, Agampodi SB. Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period. PLOS ONE 2022, 17: e0269888. PMID: 35834567, PMCID: PMC9282538, DOI: 10.1371/journal.pone.0269888.Peer-Reviewed Original ResearchConceptsNew-onset wheezePregnant womenSecond trimesterAsthmatic womenPregnancy outcomesPregnant asthmatic womenEligible pregnant womenProspective cohort studyLow birth weightPrevalence of wheezeEffect of asthmaRural pregnant womenMaternal care programmeCohort studyProspective cohortHospital admissionAntenatal periodAsthma prevalenceFirst trimesterBirth weightClinical assessmentHigh prevalenceWheezeAsthmaTrimesterFatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy
Koralegedara IS, Warnasekara JN, Rathnayake A, Dayaratne KG, Agampodi SB. Fatty Liver Index is a valid predictor of non-alcoholic fatty liver disease (NAFLD) in pregnancy. BMJ Open Gastroenterology 2022, 9: e000913. PMID: 35728866, PMCID: PMC9214354, DOI: 10.1136/bmjgast-2022-000913.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseFatty liver indexAdverse pregnancy outcomesFatty liver diseasePregnant womenPregnancy outcomesLiver diseaseFatty liverLiver indexFirst trimester pregnant womenGamma-glutamyl transferase levelsBody mass indexPeriod of gestationLogistic regression modelsBinary logistic regression modelIndependent predictorsMass indexPregnancy cohortEarly pregnancyMean ageTransferase levelsLiver enzymesUltrasound scanGeneral populationHealth setupDoes Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka
Gunarathne S, Amarasinghe G, Agampodi T, Wickramasinghe N, Mendis V, Prasanna I, Agampodi S. Does Being Diagnosed As Anemic in Early Pregnancy Have an Impact on the Household Expenditure for Food? Evidence From a Maternal Cohort in Rural Sri Lanka. Current Developments In Nutrition 2022, 6: 654. PMCID: PMC9193294, DOI: 10.1093/cdn/nzac061.038.Peer-Reviewed Original ResearchNon-anaemic womenEarly pregnancyPregnant womenRural Sri LankaFirst trimester pregnant womenPublic health midwivesHousehold food expenditureThird of pregnanciesAnemic pregnant womenMann-Whitney U testDiagnosis of anemiaMonthly household incomeLifestyle modificationHemoglobin levelsPregnancy cohortThird trimesterMean ageModerate anemiaMaternal cohortAppropriate treatmentHousehold economic statusNutritional educationSelf-administrated questionnairePregnancyAnemiaFeasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort
Jayasinghe I, Wickramasinghe Y, Kurera DM, Samarakoon N, Rupasinghe I, Ponmalay P, Agampodi SB. Feasibility of using telephone interviews and internet-based message services during the COVID-19 pandemic in rural Sri Lanka: experiences of the Rajarata Pregnancy Cohort. Rural And Remote Health 2022, 22: 7442. PMID: 35546146, DOI: 10.22605/rrh7442.Peer-Reviewed Original ResearchConceptsTelephone interviewsPregnancy cohortCOVID-19 pandemicTelephone-based strategyHealth message deliveryHealth promotion initiativesLow-resource settingsPregnant womenPopulation health researchersRural Sri LankaPromotion initiativesHealth disparitiesRural areasCohortSelection biasHealth researchersMiddle-income nationsPandemicDeliveryParticipantsLocal settingProper assessmentImplementation of researchSettingSri LankaCross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol.
Amarasinghe G, Mendis V, Agampodi T, Agampodi S. Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol. F1000Research 2022, 10: 223. PMID: 35528960, PMCID: PMC9039368, DOI: 10.12688/f1000research.28226.3.Peer-Reviewed Original ResearchConceptsStrong public health systemCross-sectional studyPregnant womenFirst trimesterSignificant global health problemEtiology of anemiaInterviewer-administered questionnaireComplete blood countGlobal health problemPublic health systemAnuradhapura districtDietary questionnaireFetal outcomesMaternal anemiaAntenatal careAnemia controlBlood countSectional studyAnemia casesAnemiaHealth problemsPregnancySimilar etiologyField clinicsEtiologyDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2022, 10: 1028. DOI: 10.12688/f1000research.52539.3.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralClinical examinationMedical causesEconomic burden of out-of-pocket expenditure, productivity cost during pregnancy and COVID-19 impact on household economy in a cohort of pregnant women in Anuradhapura District, Sri Lanka; A study protocol
Gunarathne SP, Wickramasinghe ND, Agampodi TC, Prasanna IR, Agampodi SB. Economic burden of out-of-pocket expenditure, productivity cost during pregnancy and COVID-19 impact on household economy in a cohort of pregnant women in Anuradhapura District, Sri Lanka; A study protocol. F1000Research 2022, 10: 700. PMID: 35528955, PMCID: PMC9046902, DOI: 10.12688/f1000research.53320.3.Peer-Reviewed Original ResearchConceptsPregnant womenMaternal healthProductivity costsEconomic burdenHealth servicesPocket expenditureCOVID-19 outbreakCross-sectional studyAnuradhapura districtTerms of absenteeismHealth care practitionersFree health servicesLack of evidenceStudy protocolHealth care administratorsOngoing COVID-19 pandemicCare practitionersStudy settingCOVID-19 impactPregnancyOOPECohortMedical officersWomenStudy sampleNon-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothers