2024
Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. PMID: 38504849, PMCID: PMC10948970, DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referral
2023
Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo)
Agampodi S, Wickramasinghe N, Agampodi T. Cohort Profile: The Rajarata Pregnancy Cohort (RaPCo). Anuradhapura Medical Journal 2023, 17: 31. DOI: 10.4038/amj.v17i1.7757.Peer-Reviewed Original ResearchMaternal morbidityFirst trimesterPregnancy cohortPregnant womenFirst antenatal clinic visitEarly pregnancy miscarriageFatty liver gradePregnancy care programsFatty liver indexGestational age neonatesAntenatal clinic visitPregnancy outcome dataAnemic pregnant womenSignificant risk factorsComprehensive mental healthBaseline data collectionGestational diabetesAge neonatesClinic visitsCohort womenMetabolic syndromeMetabolic derangementsEarly pregnancyEntire cohortLiver indexSerum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy
Agampodi S, Agampodi T, Amarasinghe G, Warnasekara J, Hettiarachchi A, Jayasinghe I, Koralegedara I, Abeyrathna P, Srimantha S, de Silva F, Gunarathne S, Wickramasinghe N. Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy. PLOS Global Public Health 2023, 3: e0000443. PMID: 36962935, PMCID: PMC10021427, DOI: 10.1371/journal.pgph.0000443.Peer-Reviewed Original ResearchGlomerular filtration rateWeeks of gestationRenal functionPregnant womenNonpregnant womenSerum creatinineSecond trimesterEarly pregnancyFiltration rateClinical practiceCommunity-based prospective cohort studyProspective population-based studyPre-existing medical conditionsProspective cohort studyHealthy pregnant womenCommunity-based cohortPopulation-based studyDifferent age strataMean eGFRCohort studyNewborn outcomesNonpregnant groupPregnancy cohortFirst trimesterMean SCr
2022
Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period
Rajapakse S, Wickramasinghe N, Warnasekara J, Abeyrathna P, Amarasinghe G, Hettiarachchi AU, Jayasinghe IU, Koralegedara I, Agampodi TC, Agampodi SB. Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period. PLOS ONE 2022, 17: e0269888. PMID: 35834567, PMCID: PMC9282538, DOI: 10.1371/journal.pone.0269888.Peer-Reviewed Original ResearchConceptsNew-onset wheezePregnant womenSecond trimesterAsthmatic womenPregnancy outcomesPregnant asthmatic womenEligible pregnant womenProspective cohort studyLow birth weightPrevalence of wheezeEffect of asthmaRural pregnant womenMaternal care programmeCohort studyProspective cohortHospital admissionAntenatal periodAsthma prevalenceFirst trimesterBirth weightClinical assessmentHigh prevalenceWheezeAsthmaTrimesterCross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol.
Amarasinghe G, Mendis V, Agampodi T, Agampodi S. Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol. F1000Research 2022, 10: 223. PMID: 35528960, PMCID: PMC9039368, DOI: 10.12688/f1000research.28226.3.Peer-Reviewed Original ResearchConceptsStrong public health systemCross-sectional studyPregnant womenFirst trimesterSignificant global health problemEtiology of anemiaInterviewer-administered questionnaireComplete blood countGlobal health problemPublic health systemAnuradhapura districtDietary questionnaireFetal outcomesMaternal anemiaAntenatal careAnemia controlBlood countSectional studyAnemia casesAnemiaHealth problemsPregnancySimilar etiologyField clinicsEtiologyDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2022, 10: 1028. DOI: 10.12688/f1000research.52539.3.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralClinical examinationMedical causesEarly pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates
Jayasinghe IU, Koralegedara IS, Agampodi SB. Early pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates. Acta Diabetologica 2022, 59: 535-543. PMID: 34973071, PMCID: PMC8917036, DOI: 10.1007/s00592-021-01828-1.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusGestational age neonatesLGA neonatesAge neonatesGestational ageFirst trimesterPrevalence of GDMWorld Health Organization criteriaDelivery gestational ageNeonatal birth weightPregnancy Study GroupsBirth weight centileMedian gestational ageProspective cohort studyAttributable risk percentageHigh-risk populationUndiagnosed DMCohort studyCumulative incidenceDiabetes mellitusWeight centileEarly pregnancyPregnant womenMean ageOrganization criteria
2021
Disease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2021, 10: 1028. DOI: 10.12688/f1000research.52539.1.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralCross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol
Amarasinghe G, Mendis V, Agampodi T, Agampodi S. Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol. F1000Research 2021, 10: 223. DOI: 10.12688/f1000research.28226.2.Peer-Reviewed Original ResearchStrong public health systemCross-sectional studyPregnant womenFirst trimesterSignificant global health problemEtiology of anemiaInterviewer-administered questionnaireComplete blood countGlobal health problemPublic health systemAnuradhapura districtDietary questionnaireFetal outcomesMaternal anemiaAntenatal careAnemia controlBlood countSectional studyAnemia casesAnemiaHealth problemsPregnancySimilar etiologyField clinicsEtiology
2020
The Rajarata Pregnancy Cohort (RaPCo): study protocol
Agampodi TC, Wickramasinghe ND, Prasanna RIR, Irangani MKL, Banda JMS, Jayathilake PMB, Hettiarachchi A, Amarasinghe G, Jayasinghe I, Koralagedara I, Gunarathne SP, Wickramage S, Warnasekara J, Lokunarangoda N, Mendis V, Dissanayaka AK, Premadasa J, Hettigama N, Koralagedara D, Weerasinghe M, Malawanage K, Jayakodi H, Wickramasinghe A, Agampodi SB. The Rajarata Pregnancy Cohort (RaPCo): study protocol. BMC Pregnancy And Childbirth 2020, 20: 374. PMID: 32586287, PMCID: PMC7318435, DOI: 10.1186/s12884-020-03056-x.Peer-Reviewed Original ResearchConceptsMaternal mental healthMaternal deathsMental healthSocial determinantsPregnancy cohortObstetric transitionEligible pregnant womenProspective cohort studyMaternal health outcomesMaternal mortality ratePreventable maternal deathsMaternal care programmeChild outcome dataAntenatal depressionCohort studyMiddle-income countriesFirst trimesterNeonatal periodPregnant womenClinical examinationMaternal healthEarly postpartumMaternal cohortStudy protocolMethodsThe studyFemale Obesity: An Emerging Threat in Sri Lanka
Jayasinghe I, Hettiarachchi A, Koralegedara I, Amarasinghe G, Agampodi T, Dissanayake K, Warnasekara J, Wickramasinghe N, Abeyrathne P, Agampodi S. Female Obesity: An Emerging Threat in Sri Lanka. Current Developments In Nutrition 2020, 4: nzaa063_043. PMCID: PMC7259207, DOI: 10.1093/cdn/nzaa063_043.Peer-Reviewed Original ResearchObesity grade IPrevalence of overweightBurden of overweightPrevalence of underweightMaternal health programsPeriod of gestationBurden of malnutritionLow educational levelPublic health systemCross-sectional analysisDedicated clinicCentral obesityOngoing cohortMiddle-income countriesWaist circumferenceFirst trimesterPregnant womenMean agePregnant mothersBody of evidenceAnthropometric assessmentGrade IHigh riskObesityHealth programs