2024
The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment
Schoretsanitis G, Correll C, Agorastos A, Sanchez A, Erzin G, Grigoras R, Benussi M, Gondek T, Guloksuz S, Højlund M, Jerotic S, Kilic O, Metaj E, Sidhu D, Skandali N, Skuhareuski A, Tveito M, Wolthusen R, Communication and Publications E, Chumakov E, de Filippis R. The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment. The World Journal Of Biological Psychiatry 2024, 25: 342-351. PMID: 38905131, DOI: 10.1080/15622975.2024.2367138.Peer-Reviewed Original ResearchConceptsEuropean Psychiatric AssociationAntipsychotic treatmentPsychiatrists' attitudesTherapeutic drug monitoringEarly-career psychiatristsExploratory factor analysisBenefit of therapeutic drug monitoringPsychiatric AssociationAntipsychoticsNegative expectationsAssociated with frequencyTDM useDrug monitoringTherapeutic drug monitoring useFactor analysisBeliefs of patientsHigh-income countriesLow-/middle-income countriesResponse varianceClinical benefitClozapineOutpatient settingLinear regression analysisClinical settingPsychiatrists
2023
Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study
Fusar-Poli L, Prachason T, Erzin G, Pries L, Brondino N, Politi P, Delespaul P, Kenis G, Luykx J, Lin B, Richards A, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak S, Mihaljevic M, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz P, García-Portilla M, Sanjuan J, Escarti M, Santos J, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric N, Atbaşoğlu C, Üçok A, Alptekin K, Saka M, Arango C, O'Donovan M, van Os J, Rutten B, Guloksuz S, investigators G. Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. Psychiatry Research 2023, 323: 115184. PMID: 37015164, DOI: 10.1016/j.psychres.2023.115184.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesCognitionCognition DisordersCross-Sectional StudiesExposomeFemaleHumansMaleSchizophreniaSchizophrenic PsychologySiblingsConceptsBenton Facial Recognition TestDegraded Facial Affect Recognition TaskWechsler Adult Intelligence Scale-Third EditionSchizophrenia spectrum disordersSocial cognitionCognitive domainsFacial affect recognition taskAffect recognition taskFacial Recognition TestCognitive impairmentRecognition testSpectrum disorderRecognition taskCross-sectional sampleHealthy controlsCognitionPsychosis spectrumShort versionUnaffected siblingsNeurocognitionEUGEI studySchizophreniaPerceptionImpairmentSiblings
2022
The association between cannabis use and facial emotion recognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study
Fusar-Poli L, Pries LK, van Os J, Radhakrishnan R, Pençe AY, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Üçok A, Alptekin K, Saka MC, investigators G, Aguglia E, Arango C, Rutten BP, Guloksuz S. The association between cannabis use and facial emotion recognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study. European Neuropsychopharmacology 2022, 63: 47-59. PMID: 36055075, DOI: 10.1016/j.euroneuro.2022.08.003.Peer-Reviewed Original ResearchMeSH KeywordsCannabinoid Receptor AgonistsCannabisCross-Sectional StudiesEmotionsFacial RecognitionHumansPsychotic DisordersSchizophreniaSiblingsConceptsHealthy controlsCannabis useDegraded Facial Affect Recognition TaskPresent cross-sectional studyCross-sectional studyHigh genetic riskProgression of schizophreniaRegular cannabis useCognitive disturbancesRegular cannabisPsychosis riskPatientsSchizophreniaFacial emotion recognition performanceGenetic riskCannabisCurrent cannabisEUGEI studyLongitudinal studyAgeSiblingsAssociationRiskOnsetEffect relationship
2021
Association between exposome score for schizophrenia and functioning in first-episode psychosis: results from the Athens first-episode psychosis research study
Erzin G, Pries L, Dimitrakopoulos S, Ralli I, Xenaki L, Soldatos R, Vlachos I, Selakovic M, Foteli S, Kosteletos I, Nianiakas N, Mantonakis L, Rizos E, Kollias K, Van Os J, Guloksuz S, Stefanis N. Association between exposome score for schizophrenia and functioning in first-episode psychosis: results from the Athens first-episode psychosis research study. Psychological Medicine 2021, 53: 2609-2618. PMID: 34789350, PMCID: PMC10123830, DOI: 10.1017/s0033291721004542.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesEthnicityExposomeHumansMinority GroupsPsychotic DisordersSchizophreniaAssociation Between Discrimination Stress and Suicidality in Preadolescent Children
Argabright S, Visoki E, Moore T, Ryan D, DiDomenico G, Njoroge W, Taylor J, Guloksuz S, Gur R, Gur R, Benton T, Barzilay R. Association Between Discrimination Stress and Suicidality in Preadolescent Children. Journal Of The American Academy Of Child & Adolescent Psychiatry 2021, 61: 686-697. PMID: 34425231, PMCID: PMC8917360, DOI: 10.1016/j.jaac.2021.08.011.Peer-Reviewed Original ResearchLongitudinal associations between alcohol use, smoking, genetic risk scoring and symptoms of depression in the general population: a prospective 6-year cohort study
de Boer N, Vermeulen J, Lin B, van Os J, Have M, de Graaf R, van Dorsselaer S, Bak M, Rutten B, Batalla A, Guloksuz S, Luykx J. Longitudinal associations between alcohol use, smoking, genetic risk scoring and symptoms of depression in the general population: a prospective 6-year cohort study. Psychological Medicine 2021, 53: 1409-1417. PMID: 35023464, PMCID: PMC10009403, DOI: 10.1017/s0033291721002968.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingCohort StudiesCross-Sectional StudiesDepressionHumansLongitudinal StudiesProspective StudiesRisk FactorsSmokingConceptsNumber of cigarettesDepressive symptomsAlcohol useLongitudinal associationsGeneral populationSmoking behaviorAlcohol consumptionGenetic risk scoringSymptoms of depressionGenetic risk score analysisGenetic risk scoreAlcohol cessationCohort studySmoking statusGlobal burdenMood disordersRisk scoreSmokingModerate drinkingRisk score analysisLess symptomsLinear mixed effects modelsSymptomsScore analysisRisk scoring
2020
Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia
Sahbaz C, Zibandey N, Kurtulmus A, Duran Y, Gokalp M, Kırpınar I, Sahin F, Guloksuz S, Akkoc T. Reduced regulatory T cells with increased proinflammatory response in patients with schizophrenia. Psychopharmacology 2020, 237: 1861-1871. PMID: 32221694, DOI: 10.1007/s00213-020-05504-0.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsRegulatory T cellsHealthy controlsT cellsIL-17AIL-6Smoking status-matched healthy controlsCulture supernatant levelsT cell percentageTh1/Th2Levels of Foxp3Blood mononuclear cellsBody mass indexImmune imbalanceTreg percentageMass indexProinflammatory cytokinesMethodsForty patientsMononuclear cellsPlasma levelsProinflammatory responseSupernatant levelsCell percentageResultsIn comparisonArray kit
2015
Pharmaceutical industry interactions of psychiatric trainees from 20 European countries
Riese F, Guloksuz S, Roventa C, Fair J, Haravuori H, Rolko T, Flynn D, Giacco D, Banjac V, Jovanovic N, Bayat N, Palumbo C, Rusaka M, Kilic O, Augėnaitė J, Nawka A, Zenger M, Kekin I, Wuyts P, Barrett E, Bausch-Becker N, Mikaliūnas J, del Valle E, Feffer K, Lomax G, Marques J, Jauhar S. Pharmaceutical industry interactions of psychiatric trainees from 20 European countries. European Psychiatry 2015, 30: 284-290. PMID: 25456156, DOI: 10.1016/j.eurpsy.2014.09.417.Peer-Reviewed Original Research
2012
Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence?
Jauhar S, Guloksuz S, Andlauer O, Lydall G, Marques J, Mendonca L, Dumitrescu I, Roventa C, De Vriendt N, Van Zanten J, Riese F, Nwachukwu I, Nawka A, Psaras R, Masson N, Krishnadas R, Volpe U, European Federation of Psychiatric Trainees' Research Group. Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence? BMC Psychiatry 2012, 12: 27. PMID: 22463055, PMCID: PMC3337226, DOI: 10.1186/1471-244x-12-27.Peer-Reviewed Original ResearchConceptsSecond-generation antipsychoticsCognitive behavioral therapyUse of SGAsSecond-generation antipsychotic medicationsKnowledge of trialQuestionnaire-based studyAntipsychotic medicationAntipsychotic treatmentTreatment choicePatientsBehavioral therapyForms of psychotherapyOwn treatmentAntipsychoticsTreatmentPsychosisTrialsPsychiatry traineesEfficacyTrainees