2024
The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment
Schoretsanitis G, Correll C, Agorastos A, Sanchez A, Erzin G, Grigoras R, Benussi M, Gondek T, Guloksuz S, Højlund M, Jerotic S, Kilic O, Metaj E, Sidhu D, Skandali N, Skuhareuski A, Tveito M, Wolthusen R, Communication and Publications E, Chumakov E, de Filippis R. The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment. The World Journal Of Biological Psychiatry 2024, 25: 342-351. PMID: 38905131, DOI: 10.1080/15622975.2024.2367138.Peer-Reviewed Original ResearchConceptsEuropean Psychiatric AssociationAntipsychotic treatmentPsychiatrists' attitudesTherapeutic drug monitoringEarly-career psychiatristsExploratory factor analysisBenefit of therapeutic drug monitoringPsychiatric AssociationAntipsychoticsNegative expectationsAssociated with frequencyTDM useDrug monitoringTherapeutic drug monitoring useFactor analysisBeliefs of patientsHigh-income countriesLow-/middle-income countriesResponse varianceClinical benefitClozapineOutpatient settingLinear regression analysisClinical settingPsychiatrists
2022
Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype?
Fusar-Poli L, Rutten B, van Os J, Aguglia E, Guloksuz S. Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype? International Review Of Psychiatry 2022, 34: 663-675. PMID: 36786114, DOI: 10.1080/09540261.2022.2101352.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresTreatment responseRisk scoreMental disordersDetailed clinical characterizationPresent narrative reviewPotential clinical utilityMajor mental disordersIndividual genetic predispositionRisk stratificationPrognostic evaluationClinical characterizationWide association study datasetsClinical utilityGeneral populationGenetic predispositionNarrative reviewSingle nucleotide polymorphismsSchizophrenia as a symptom of psychiatry’s reluctance to enter the moral era of medicine
van Os J, Guloksuz S. Schizophrenia as a symptom of psychiatry’s reluctance to enter the moral era of medicine. Schizophrenia Research 2022, 242: 138-140. PMID: 34991949, DOI: 10.1016/j.schres.2021.12.017.Peer-Reviewed Original ResearchInterplay between genetic background and environmental factors in psychiatry: current situation and future prospects.
Rutten B, Guloksuz S, Boks M, van Os J, Luykx J, van Winkel R. Interplay between genetic background and environmental factors in psychiatry: current situation and future prospects. Tijdschrift Voor Psychiatrie 2022, 64: 317-322. PMID: 35735044.Peer-Reviewed Original Research
2021
Medication strategies in first episode psychosis patients: A survey among psychiatrists
Kikkert M, Veling W, de Haan L, Begemann M, de Koning M, Sommer I, de Haan L, Veling W, van Os J, Smit F, Begemann M, Schuite‐Koops S, Marcelis M, Kikkert M, van Beveren N, Boonstra N, Rosema B, Bakker P, Gülöksüz S, Lokkerbol J, Brand B, Gangadin S, Geraets C, Hag E, Oomen P, Voppel A, van Amelsvoort T, Bak M, Been A, van den Bosch M, van den Brink T, Faber G, Grootens K, de Jonge M, Knegtering H, Kurkamp J, Mahabir A, Pijnenborg G, Staring T, Vaes W, Veen N, Veerman S, Wiersma S, Sommer I. Medication strategies in first episode psychosis patients: A survey among psychiatrists. Early Intervention In Psychiatry 2021, 16: 139-146. PMID: 33754470, PMCID: PMC9292219, DOI: 10.1111/eip.13138.Peer-Reviewed Original ResearchMeSH KeywordsAntipsychotic AgentsHumansPsychiatryPsychotic DisordersRemission InductionSurveys and QuestionnairesConceptsFirst psychotic episodeMedication discontinuationMedication strategiesPsychotic episodeFirst-episode psychosis patientsEpisode psychosis patientsSubstantial practice variationFirst-episode patientsMonths of remissionFirst-episode psychosisSpecific treatment strategiesSubsample of patientsPractice of cliniciansMaintenance therapyEarly discontinuationPsychosis patientsAntipsychotic drugsEpisode psychosisTreatment strategiesReduced dosePractice variationLong-term effectsSame doseDiscontinuationMost guidelines
2019
What is the role of personal characteristics of psychiatric trainees in Turkey on their mobility and migration?
Kilic O, Sonmez E, Erzin G, Guloksuz S, Pinto da Costa M. What is the role of personal characteristics of psychiatric trainees in Turkey on their mobility and migration? Asian Journal Of Psychiatry 2019, 42: 30-31. PMID: 30951929, DOI: 10.1016/j.ajp.2019.03.020.Peer-Reviewed Original ResearchConceptsPsychiatric trainees
2018
The Exposome Paradigm and the Complexities of Environmental Research in Psychiatry
Guloksuz S, van Os J, Rutten B. The Exposome Paradigm and the Complexities of Environmental Research in Psychiatry. JAMA Psychiatry 2018, 75: 985-986. PMID: 29874362, DOI: 10.1001/jamapsychiatry.2018.1211.Peer-Reviewed Original ResearchThe Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments
Guloksuz S, Rutten B, Pries L, Have M, de Graaf R, van Dorsselaer S, Klingenberg B, van Os J, Ioannidis J, Group T. The Complexities of Evaluating the Exposome in Psychiatry: A Data-Driven Illustration of Challenges and Some Propositions for Amendments. Schizophrenia Bulletin 2018, 44: 1175-1179. PMID: 30169883, PMCID: PMC6192470, DOI: 10.1093/schbul/sby118.Peer-Reviewed Original ResearchConceptsMental health outcomesHealth outcomesNetherlands Mental Health SurveyMental Health SurveyPre-specified analysis planFalsification endpointsModifiable factorsSources of heterogeneityHealth SurveyIntervention effectsSelective reportingAnalysis planP-valueOutcomesEffect sizeVibration of effectsAnalytical planSame outcomeDifferent studiesExploratory analysisExposureStudy 2 dataP-value thresholdMobility trends of psychiatric trainees in Turkey: hard to leave, harder to stay?
Kilic O, Sonmez E, Erzin G, Guloksuz S, Pinto da Costa M. Mobility trends of psychiatric trainees in Turkey: hard to leave, harder to stay? European Archives Of Psychiatry And Clinical Neuroscience 2018, 269: 367-369. PMID: 29938296, DOI: 10.1007/s00406-018-0914-2.Peer-Reviewed Original Research
2017
Application of network methods for understanding mental disorders: pitfalls and promise
Guloksuz S, Pries L, van Os J. Application of network methods for understanding mental disorders: pitfalls and promise. Psychological Medicine 2017, 47: 2743-2752. PMID: 28578740, DOI: 10.1017/s0033291717001350.Peer-Reviewed Original Research
2015
Pharmaceutical industry interactions of psychiatric trainees from 20 European countries
Riese F, Guloksuz S, Roventa C, Fair J, Haravuori H, Rolko T, Flynn D, Giacco D, Banjac V, Jovanovic N, Bayat N, Palumbo C, Rusaka M, Kilic O, Augėnaitė J, Nawka A, Zenger M, Kekin I, Wuyts P, Barrett E, Bausch-Becker N, Mikaliūnas J, del Valle E, Feffer K, Lomax G, Marques J, Jauhar S. Pharmaceutical industry interactions of psychiatric trainees from 20 European countries. European Psychiatry 2015, 30: 284-290. PMID: 25456156, DOI: 10.1016/j.eurpsy.2014.09.417.Peer-Reviewed Original Research
2013
Science, Psychiatry, and the DSM.
Atbaşoğlu E, Gülöksüz S. Science, Psychiatry, and the DSM. Turkish Journal Of Psychiatry 2013, 24: 202-12. PMID: 24049010, DOI: 10.5080/u7220.Peer-Reviewed Original ResearchMeSH KeywordsDiagnostic and Statistical Manual of Mental DisordersHumansMental DisordersPsychiatryScienceTurkeyConceptsGeneral medical conditionsGood vantage pointContemporary psychiatryBranches of medicineDetailed medical assessmentGeneral medical diagnosisVantage pointPsychiatryMedical conditionsApproach todayDSM disordersMedical assessmentStructural abnormalitiesMental disordersBiopsychosocial approachPsychiatric phenomenaSpecific causesStatistical ManualDiagnostic reliabilityScientific problemsDimensions of moodDisordersScienceMain scientific problemsDisciplines
2012
Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence?
Jauhar S, Guloksuz S, Andlauer O, Lydall G, Marques J, Mendonca L, Dumitrescu I, Roventa C, De Vriendt N, Van Zanten J, Riese F, Nwachukwu I, Nawka A, Psaras R, Masson N, Krishnadas R, Volpe U, European Federation of Psychiatric Trainees' Research Group. Choice of antipsychotic treatment by European psychiatry trainees: are decisions based on evidence? BMC Psychiatry 2012, 12: 27. PMID: 22463055, PMCID: PMC3337226, DOI: 10.1186/1471-244x-12-27.Peer-Reviewed Original ResearchConceptsSecond-generation antipsychoticsCognitive behavioral therapyUse of SGAsSecond-generation antipsychotic medicationsKnowledge of trialQuestionnaire-based studyAntipsychotic medicationAntipsychotic treatmentTreatment choicePatientsBehavioral therapyForms of psychotherapyOwn treatmentAntipsychoticsTreatmentPsychosisTrialsPsychiatry traineesEfficacyTrainees
2009
Attitudes and behaviors of psychiatry residents and psychiatrists working in training institutes towards the relationship between the pharmaceutical industry and physicians.
Gülöksüz S, Oral E, Ulaş H. Attitudes and behaviors of psychiatry residents and psychiatrists working in training institutes towards the relationship between the pharmaceutical industry and physicians. Turkish Journal Of Psychiatry 2009, 20: 236-42. PMID: 19757223.Peer-Reviewed Original ResearchConceptsPharmaceutical representativesPrescribing practicesSecond-year residentsHospital staffState hospital staffPhysician prescribing practicesPsychiatry residentsUniversity hospital staffBehavior of physiciansMost physiciansPharmaceutical promotionEducational meetingsDuration of residencyPhysiciansBehaviors of psychiatristsOlder residentsPsychiatristsSignificant interaction