Altered Expression of Cytokine Signaling Pathway Genes in Peripheral Blood Cells of Alcohol Dependent Subjects: Preliminary Findings
Beech RD, Qu J, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R. Altered Expression of Cytokine Signaling Pathway Genes in Peripheral Blood Cells of Alcohol Dependent Subjects: Preliminary Findings. Alcohol Clinical And Experimental Research 2012, 36: 1487-1496. PMID: 22471388, PMCID: PMC3393821, DOI: 10.1111/j.1530-0277.2012.01775.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismBlood CellsCytokinesDemographyDiagnostic and Statistical Manual of Mental DisordersEthnicityFemaleGene ExpressionGene Expression ProfilingHumansInterleukin-15InterleukinsJanus KinasesMaleMicroarray AnalysisMiddle AgedRecurrenceSignal TransductionSTAT Transcription FactorsYoung AdultConceptsGroups of subjectsMD subjectsAlcohol dependenceGeneGo MetaCore softwareEnd-organ damageChronic alcohol abusePeripheral blood cellsInnate immune responseAlcohol-dependent subjectsHeavy alcohol useT cell receptorPeripheral bloodClinical studiesImmune responseJanus kinase-signal transducerHigh riskImmune functionModerate drinkersHD subjectsAlcohol abuseAlcohol consumptionHeavy drinkersKinase-signal transducerDependent subjectsSignaling Pathway Genes