Featured Publications
Distinct neural networks predict cocaine versus cannabis treatment outcomes
Lichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingCognitive behavior therapyCognitive behavioral therapySubstance use disordersCannabis abstinenceNeural mechanismsBehavior therapyDistinct neural networksComputer-based trainingCannabis use disorderFMRI scanningNeural predictorsStudy 1Study 2Treatment outcomesContingency managementPrior workComparison subjectsNetwork strengthUse disordersNovel treatment targetsAbstinenceIndependent samplesCocaine abstinenceTreatment responders
2019
Gambling disorder
Potenza MN, Balodis IM, Derevensky J, Grant JE, Petry NM, Verdejo-Garcia A, Yip SW. Gambling disorder. Nature Reviews Disease Primers 2019, 5: 51. PMID: 31346179, DOI: 10.1038/s41572-019-0099-7.Peer-Reviewed Original ResearchConceptsPlacebo-controlled trialOpioid receptor antagonistGambling disorderCognitive behavioral therapyPharmacological therapyLimbic structuresPsychiatric disordersAdult populationSubstantial distressClinical settingBehavioral interventionsTreatment effortsDisordersTherapyPoor qualityFormal indicationNeurobiological studiesTreatmentImproved identificationMedicationsPathophysiologyEtiologyAntagonistPrevalenceGamblers Anonymous