Cocaine Augments Dopamine-Mediated Inhibition of Neuronal Activity in the Dorsal Bed Nucleus of the Stria Terminalis
Melchior J, Perez R, Salimando G, Luchsinger J, Basu A, Winder D. Cocaine Augments Dopamine-Mediated Inhibition of Neuronal Activity in the Dorsal Bed Nucleus of the Stria Terminalis. Journal Of Neuroscience 2021, 41: 5876-5893. PMID: 34035141, PMCID: PMC8265809, DOI: 10.1523/jneurosci.0284-21.2021.Peer-Reviewed Original ResearchDorsal bed nucleusBed nucleusStria terminalisDopaminergic inputAutoreceptor activationCocaine administrationD2/D3 receptor antagonist racloprideDopamine-mediated inhibitionSubstantial dopaminergic inputReceptor antagonist racloprideDrug-induced elevationAcute cocaine administrationMale C57BL6 micePopulation activityCalcium transient activityDrug reward pathwaysWhole-cell electrophysiologyMouse brain slicesCellular inhibitionOutward membrane currentsAntagonist racloprideDopamine terminalsSaline administrationC57BL6 miceCatecholamine release