2013
Parvovirus evades interferon-dependent viral control in primary mouse embryonic fibroblasts
Mattei LM, Cotmore SF, Tattersall P, Iwasaki A. Parvovirus evades interferon-dependent viral control in primary mouse embryonic fibroblasts. Virology 2013, 442: 20-27. PMID: 23676303, PMCID: PMC3767977, DOI: 10.1016/j.virol.2013.03.020.Peer-Reviewed Original ResearchConceptsType I IFNsI IFNsI interferonIFN responseAntiviral immune mechanismsType I interferonInnate defense mechanismsMouse embryonic fibroblastsMVMp infectionViral controlImmune mechanismsInnate sensingAntiviral programViral replicationViral sensorsMurine parvovirusPoly (I:C) stimulationVirusEmbryonic fibroblastsType IMiceDefense mechanismsMinute virusMVMpPrimary mouse embryonic fibroblasts
1999
Controlled Conformational Transitions in the MVM Virion Expose the VP1 N-Terminus and Viral Genome without Particle Disassembly
Cotmore S, D'Abramo A, Ticknor C, Tattersall P. Controlled Conformational Transitions in the MVM Virion Expose the VP1 N-Terminus and Viral Genome without Particle Disassembly. Virology 1999, 254: 169-181. PMID: 9927584, DOI: 10.1006/viro.1998.9520.Peer-Reviewed Original ResearchConceptsViral particlesPrior treatmentAntigenic determinantsCapsid protein VP1Empty viral particlesParvovirus minute virusBrief exposureInfectious virionsIndividual polypeptide speciesSerumProtein VP1Proportion of virionsVirusVirionsEpitope accessibilityMinute virusApparent integrityViral genomeGreat majorityVP1ProportionMice
1992
Two amino acid substitutions within the capsid are coordinately required for acquisition of fibrotropism by the lymphotropic strain of minute virus of mice
Ball-Goodrich L, Tattersall P. Two amino acid substitutions within the capsid are coordinately required for acquisition of fibrotropism by the lymphotropic strain of minute virus of mice. Journal Of Virology 1992, 66: 3415-3423. PMID: 1316457, PMCID: PMC241122, DOI: 10.1128/jvi.66.6.3415-3423.1992.Peer-Reviewed Original ResearchConceptsRestrictive infectionDouble mutant virusLymphotropic strainViral life cycleMinute virusInfectionImmunosuppressive strainFibroblast infectionVirusParvovirus minute virusMutant virusA9 fibroblastsCodon 317MiceCodon 321Amino acid substitutionsFibroblastsSame cellsCapsid geneCellsGene expressionAcid substitutionsSynergistic interactionNucleotide changesA9 cellsThe pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2
Brownstein D, Smith A, Johnson E, Pintel D, Naeger L, Tattersall P. The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2. Journal Of Virology 1992, 66: 3118-3124. PMID: 1373202, PMCID: PMC241074, DOI: 10.1128/jvi.66.5.3118-3124.1992.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCapsidDNA, ViralEpitopesGenetic VariationImmunohistochemistryMiceMice, Inbred C3HMinute virus of miceMutagenesisNucleic Acid HybridizationParvoviridae InfectionsStructure-Activity RelationshipTissue DistributionViral Core ProteinsViral Nonstructural ProteinsVirulenceConceptsPathogenesis of infectionAsymptomatic infectionMultiple organsViral capsid antigenMesenteric lymph nodesSmooth muscle cellsSame target cellsMVMi infectionLymph nodesCapsid antigenMVMp infectionLethal infectionC3H/Lymphoid cellsTarget organsSimilar dosesAllotropic determinantMinute virusInfectious virusVirus titrationInfectionMuscle cellsMiceTitersTarget cells
1989
Evidence for a ligation step in the DNA replication of the autonomous parvovirus minute virus of mice
Cotmore S, Gunther M, Tattersall P. Evidence for a ligation step in the DNA replication of the autonomous parvovirus minute virus of mice. Journal Of Virology 1989, 63: 1002-1006. PMID: 2911112, PMCID: PMC247784, DOI: 10.1128/jvi.63.2.1002-1006.1989.Peer-Reviewed Original Research
1988
The terminal protein of minute virus of mice is an 83 kilodalton polypeptide linked to specific forms of double‐stranded and single‐stranded viral DNA
Gunther M, Tattersall P. The terminal protein of minute virus of mice is an 83 kilodalton polypeptide linked to specific forms of double‐stranded and single‐stranded viral DNA. FEBS Letters 1988, 242: 22-26. PMID: 3203742, DOI: 10.1016/0014-5793(88)80977-3.Peer-Reviewed Original ResearchMapping of the fibrotropic and lymphotropic host range determinants of the parvovirus minute virus of mice
Gardiner E, Tattersall P. Mapping of the fibrotropic and lymphotropic host range determinants of the parvovirus minute virus of mice. Journal Of Virology 1988, 62: 2605-2613. PMID: 3392768, PMCID: PMC253690, DOI: 10.1128/jvi.62.8.2605-2613.1988.Peer-Reviewed Original ResearchConceptsFibroblast host cellsLymphotropic strainHost cell typesLymphocyte culturesMinute virusPlaque formationTarget cell specificityChimeric viral genomesFibroblast monolayersViral growthParvovirus minute virusViral progenyVirusHost range determinantsMiceHost cellsCell specificityCell typesRecombinant virusesViral sequencesViral genomeViral promotersInfectious genomic cloneVirus structural genesRange determinantsThe NS-1 polypeptide of minute virus of mice is covalently attached to the 5' termini of duplex replicative-form DNA and progeny single strands
Cotmore S, Tattersall P. The NS-1 polypeptide of minute virus of mice is covalently attached to the 5' termini of duplex replicative-form DNA and progeny single strands. Journal Of Virology 1988, 62: 851-860. PMID: 3339715, PMCID: PMC253642, DOI: 10.1128/jvi.62.3.851-860.1988.Peer-Reviewed Original Research
1986
DNA sequence of the lymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain
Astell C, Gardiner E, Tattersall P. DNA sequence of the lymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain. Journal Of Virology 1986, 57: 656-669. PMID: 3502703, PMCID: PMC252781, DOI: 10.1128/jvi.57.2.656-669.1986.Peer-Reviewed Original Research
1984
Formation of a host range mutant of the lymphotropic strain of minute virus of mice during persistent infection in mouse L cells
Ron D, Tattersall P, Tal J. Formation of a host range mutant of the lymphotropic strain of minute virus of mice during persistent infection in mouse L cells. Journal Of Virology 1984, 52: 63-69. PMID: 6090711, PMCID: PMC254489, DOI: 10.1128/jvi.52.1.63-69.1984.Peer-Reviewed Original ResearchConceptsLymphotropic strainPersistent infectionL cellsMinute virusT lymphocyte cell lineAltered host rangeCarrier stateHigh titersMiceCarrier culturesViral host rangeVirusCell linesSingle plaqueInfectionMassive cell lysisRestriction enzyme analysisMouse L cellsCellsViral genomeCell lysisHost range mutantsDaysEnzyme analysisEarly stages
1983
Construction of an infectious molecular clone of the autonomous parvovirus minute virus of mice
Merchlinsky M, Tattersall P, Leary J, Cotmore S, Gardiner E, Ward D. Construction of an infectious molecular clone of the autonomous parvovirus minute virus of mice. Journal Of Virology 1983, 47: 227-232. PMID: 6345805, PMCID: PMC255236, DOI: 10.1128/jvi.47.1.227-232.1983.Peer-Reviewed Original ResearchInteraction of minute virus of mice with differentiated cells: strain-dependent target cell specificity is mediated by intracellular factors
Spalholz B, Tattersall P. Interaction of minute virus of mice with differentiated cells: strain-dependent target cell specificity is mediated by intracellular factors. Journal Of Virology 1983, 46: 937-943. PMID: 6602221, PMCID: PMC256568, DOI: 10.1128/jvi.46.3.937-943.1983.Peer-Reviewed Original ResearchConceptsVirus-host cell interactionsTarget cell specificityCell typesIntracellular host factorsRestrictive cell typesRestrictive infectionCell interactionsMinute virusCell specificityHost cell typesViral determinantsViral replicationSpecific receptorsImmunosuppressive strainHost factorsSame receptorViral DNA synthesisPrototype strainVirusDetectable expressionIncoming viral genomesEarly eventsFinal outcomeInfectionMiceReciprocal productive and restrictive virus-cell interactions of immunosuppressive and prototype strains of minute virus of mice
Tattersall P, Bratton J. Reciprocal productive and restrictive virus-cell interactions of immunosuppressive and prototype strains of minute virus of mice. Journal Of Virology 1983, 46: 944-955. PMID: 6602222, PMCID: PMC256569, DOI: 10.1128/jvi.46.3.944-955.1983.Peer-Reviewed Original ResearchConceptsPrototype strainImmunosuppressive strainVirus variantsStrain-specific determinantsMurine host cellsVirus-host cell interactionsVirus-cell interactionsViral antigensT cellsHost cell populationsHelper functionMinute virusTarget cell specificityInfected cellsCell phenotypeCell populationsIndistinguishable strainsHost cell phenotypeCell interactionsGenomic criteriaDifferent cell typesSimian virus 40MiceHost cellsCell specificity
1972
Replication of the Parvovirus MVM I. Dependence of Virus Multiplication and Plaque Formation on Cell Growth
Tattersall P. Replication of the Parvovirus MVM I. Dependence of Virus Multiplication and Plaque Formation on Cell Growth. Journal Of Virology 1972, 10: 586-590. PMID: 4673484, PMCID: PMC356507, DOI: 10.1128/jvi.10.4.586-590.1972.Peer-Reviewed Original Research