2024
Wilson Disease and the COVID-19 pandemic: exploring patients’ mental health and vaccination attitudes in a longitudinal study
Coskun A, Aydin A, Tosun S, To U, Rubman S, Schilsky M, Zimbrean P. Wilson Disease and the COVID-19 pandemic: exploring patients’ mental health and vaccination attitudes in a longitudinal study. Frontiers In Psychology 2024, 15: 1326802. PMID: 38803830, PMCID: PMC11129684, DOI: 10.3389/fpsyg.2024.1326802.Peer-Reviewed Original ResearchMental healthMental health of individualsMental health scalesCognitive functionVaccination ratesHealth of individualsQuality of lifeCOVID-19 pandemicStudy investigated stressLevels of stressHealth scaleChronic conditionsCOVID-19 perceptionsVaccine attitudesIncreased depressionIncome lossCOVID-19Exacerbate anxietyPositive attitudesLongitudinal studyEssential workersActive initiatorsAnxietyWD patientsDepression
2020
P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Coskun A, Patel A, Wadhwa A, Apdik T, Tomlin R, Deng Y, Gonzalez-Peralta R, Schilsky M. P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.23.Peer-Reviewed Original ResearchMental health issuesWilson's diseaseHealth issuesSeverity of liverMental health QOLPhysical health QoLReview of imagingP-QOL scoresQuality of lifeFIB4 scoreAdult patientsRegistry studyNeurological assessmentPhysical health issuesChronic diseasesOutcome measuresPatientsNeurological diseasesWD patientsQoLAssess qualityDiseaseCirrhosisSignificant differencesScores
2019
Chapter 19 Wilson Disease Psychiatric Aspects
Zimbrean P. Chapter 19 Wilson Disease Psychiatric Aspects. 2019, 215-225. DOI: 10.1016/b978-0-12-810532-0.00019-7.Peer-Reviewed Original ResearchQuality of lifeWilson's diseasePsychiatric presentationsGoals of careNewer psychotropic medicationsIrreversible cognitive declineCommon presentationNeurological findingsSymptomatic treatmentPsychotropic medicationsCurrent treatmentGeneral populationPsychiatric aspectsCognitive declineFunctional psychosesWD patientsCognitive deficitsMood instabilitySymptomsTreatmentPresentationSecondary effectsRemissionMedicationsPatientsChapter 14 Psychiatric Symptoms in WD
Zimbrean P. Chapter 14 Psychiatric Symptoms in WD. 2019, 159-170. DOI: 10.1016/b978-0-12-811077-5.00014-1.Peer-Reviewed Original ResearchWilson's diseasePsychiatric presentationsGoals of careNewer psychotropic medicationsSevere side effectsQuality of lifeIrreversible cognitive declineNeurological findingsPatients' qualitySymptomatic treatmentPsychotropic medicationsCurrent treatmentPsychiatric symptomsMood symptomsGeneral populationSide effectsFunctional psychosesCognitive declineWD patientsCognitive deficitsMood instabilitySymptomsTreatmentPresentationRemission
2013
Psychiatric aspects of Wilson disease: a review
Zimbrean PC, Schilsky ML. Psychiatric aspects of Wilson disease: a review. General Hospital Psychiatry 2013, 36: 53-62. PMID: 24120023, DOI: 10.1016/j.genhosppsych.2013.08.007.Peer-Reviewed Original ResearchConceptsPsychiatric symptomsPsychiatric manifestationsWilson's diseasePsychiatric disordersPercent of patientsTime of diagnosisDiagnosis of WDCertain gene mutationsHepatic involvementNeurologic involvementClinical presentationPsychiatric presentationsCurrent evidencePsychiatric aspectsPubMed databaseWD patientsSymptomsDiseaseDiagnosisWD diagnosisGene mutationsAverage timePatientsManifestationsDisorders