2024
Psychometric Analysis for a Standardized Approach When Evaluating Liver Transplant Candidates with Acute Alcohol-Related Hepatitis
Zimbrean P. Psychometric Analysis for a Standardized Approach When Evaluating Liver Transplant Candidates with Acute Alcohol-Related Hepatitis. Current Transplantation Reports 2024, 11: 63-76. DOI: 10.1007/s40472-024-00433-9.Peer-Reviewed Original ResearchAcute alcoholic hepatitisLiver transplantationPatients' mental health statusAlcohol-related hepatitisRisk of relapseMental health statusPost-transplant factorsPsychometric instrumentsManagement of patientsCare of patientsSustained alcohol abstinenceLiver transplant candidatesLT patientsTransplant settingChronic painAlcohol relapseAlcohol abstinenceAlcoholic hepatitisLT candidatesHealth statusDiagnostic accuracyTransplant candidatesPsychometric analysisRisk factorsPatients
2023
ACLP Best Practice Guidance: Evaluation and Treatment of Depression in Solid Organ Transplant Recipients
Zimbrean P, Andrews S, Hussain F, Fireman M, Kuntz K, Niazi S, Simpson S, Soeprono T, Winder G, Jowsey-Gregoire S. ACLP Best Practice Guidance: Evaluation and Treatment of Depression in Solid Organ Transplant Recipients. Journal Of The Academy Of Consultation-Liaison Psychiatry 2023, 64: 357-370. PMID: 37003570, DOI: 10.1016/j.jaclp.2023.03.007.Peer-Reviewed Original ResearchConceptsOrgan transplant recipientsSolid organ transplant recipientsTransplant recipientsDepressive disorderFirst-line antidepressantsTreatment of depressionMental health carePosttransplant depressionSOT recipientsTransplant patientsTreating providerClinical evaluationPositive screeningTreatment interventionsPatientsRecipientsHealth careDepressionDisordersConsensus processFrequent problemSpecial Interest GroupTreatmentPractice guidanceBest practice guidance
2022
Major Depressive Disorder in an International Multisite Wilson Disease Registry
Camarata M, Ala A, Coskun A, Deng Y, Embel V, Gonzalez-Peralta R, Maciejewski K, Patel A, Rubman S, To U, Tomlin R, Schilsky M, Zimbrean P. Major Depressive Disorder in an International Multisite Wilson Disease Registry. Journal Of The Academy Of Consultation-Liaison Psychiatry 2022, 64: 106-117. PMID: 36521682, DOI: 10.1016/j.jaclp.2022.12.001.Peer-Reviewed Original ResearchConceptsMajor depressive disorderWilson's diseaseDepressive disorderLifetime major depressive disorderMental health QOLPhysical health QoLMajor depressive episodeMental health qualityStructured psychiatric evaluationSignificant differencesCross-sectional reportsLiver testsLiver diseaseNeurological assessmentLife scoresClinical correlatesDepressive episodePsychiatric symptomsPsychiatric evaluationDisease RegistrySevere anxietyLaboratory testsLifetime historySignificant associationPatientsCannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations
Winder GS, Andrews SR, Banerjee AG, Hussain F, Ivkovic A, Kuntz K, Omary L, Shenoy A, Thant T, VandenBerg A, Zimbrean P. Cannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations. Transplantation Reviews 2022, 36: 100715. PMID: 35853383, DOI: 10.1016/j.trre.2022.100715.Peer-Reviewed Original ResearchConceptsSolid organ transplantationCannabinoid useOrgan transplantationClinical careUS transplantation centersSOT patientsKidney transplantationTransplantation centersCannabinoid effectsClinical impactClinicians' perceptionsMedical literaturePatientsTransplantationCliniciansCannabinoidsCareInterprofessional issuesPsychiatric perspectiveFuture studiesUse ratesProfessional societiesSystematized reviewOngoing dilemmaRecommendationsSubstance use screening in transplant populations: Recommendations from a consensus workgroup
Jowsey-Gregoire S, Jannetto PJ, Jesse MT, Fleming J, Winder GS, Balliet W, Kuntz K, Vasquez A, Weinland S, Hussain F, Weinrieb R, Fireman M, Nickels MW, Peipert JD, Thomas C, Zimbrean PC. Substance use screening in transplant populations: Recommendations from a consensus workgroup. Transplantation Reviews 2022, 36: 100694. PMID: 35537285, DOI: 10.1016/j.trre.2022.100694.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersTransplant patientsDrug testingConsultation-liaison psychiatryTransplant populationTransplant teamClinical historyOptimal carePatient practicesPatientsCurrent laboratory testingAmerican SocietyDisordersTransplantationPharmacy communityPossible risksInsurance issuesLaboratory testingOngoing testingRiskCertain substancesGroup discussionsTestingSubstancesGambling Disorders in Organ Transplant Recipients
Luchsinger W, Zimbrean P. Gambling Disorders in Organ Transplant Recipients. 2022, 183-188. DOI: 10.1007/978-3-031-15052-4_23.ChaptersMood Disorders in Transplantation: Bipolar Disorder Spectrum
Dahal R, Zimbrean P. Mood Disorders in Transplantation: Bipolar Disorder Spectrum. 2022, 13-22. DOI: 10.1007/978-3-031-15052-4_2.ChaptersBipolar disorderEnd-stage organ failureNeuropsychiatric adverse effectsRole of psychotropicsOrgan transplant recipientsSolid organ transplantationStandard immunosuppressantsPharmacological managementTransplant outcomesTransplant recipientsOrgan failureDisease burdenBipolar disorder spectrumSuccessful transplantationOrgan transplantationMood disordersGeneral populationTransplantationPatientsAdverse effectsDisorder spectrumDisordersPsychological effectsNonadherenceImmunosuppressants
2021
Management of Substance Use Disorders in a Patient With Left Ventricular Assist Device
Choi J, Alexis J, Gosev I, Zimbrean P, Nickels M. Management of Substance Use Disorders in a Patient With Left Ventricular Assist Device. Journal Of The Academy Of Consultation-Liaison Psychiatry 2021, 62: 568-576. PMID: 34391977, DOI: 10.1016/j.jaclp.2021.07.015.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersVentricular assist deviceHeart failureAssist deviceAdvanced heart failureChallenging patient populationHeart failure managementRole of LVADsLVAD candidatesConsultation-liaison psychiatryCardiac surgeryPatient populationPatient outcomesClinical casesPatientsFailure managementDisordersLVADAvailable literatureTreatmentLimited literatureSurgeryFailureManagementIdentifying the Most Important Consultation-Liaison Psychiatry Publications in 2020 Using a Novel Literature Assessment Instrument
Simpson SA, Bienvenu OJ, Andrews SR, Close JS, Adler Cohen MA, Fernandez-Robles C, Francis BA, Gandhi J, Gangopadhyay M, Gershengoren L, Grimaldi JA, Isenberg-Grzeda E, Key RG, Kiong T, Kontos N, Loh RM, Luchsinger W, Munjal S, Niazi SK, Nichols NA, Pathare A, Pereira LF, Shim JJ, Tobin MB, Zimbrean PC. Identifying the Most Important Consultation-Liaison Psychiatry Publications in 2020 Using a Novel Literature Assessment Instrument. Journal Of The Academy Of Consultation-Liaison Psychiatry 2021, 62: 493-500. PMID: 34048960, DOI: 10.1016/j.jaclp.2021.03.006.Peer-Reviewed Original ResearchConceptsConsultation-liaison psychiatryEvidence-based careSevere mental illnessConsultation-liaison psychiatristsExcellent interrater reliabilityComplex patientsEvidence-based practiceLithium treatmentAssessment instrumentsClinical practiceClinical importanceMedical riskMental illnessMedical settingsPractice areaQuality InstrumentArticles of interestInterrater reliabilityStandardized assessmentCOVID-19PatientsAggregate scoreLiterature reviewGuidelinesPsychiatry
2020
P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Coskun A, Patel A, Wadhwa A, Apdik T, Tomlin R, Deng Y, Gonzalez-Peralta R, Schilsky M. P12 Effect of liver disease, neurological disease and mental health issues on quality of life in patients with wilson disease. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.23.Peer-Reviewed Original ResearchMental health issuesWilson's diseaseHealth issuesSeverity of liverMental health QOLPhysical health QoLReview of imagingP-QOL scoresQuality of lifeFIB4 scoreAdult patientsRegistry studyNeurological assessmentPhysical health issuesChronic diseasesOutcome measuresPatientsNeurological diseasesWD patientsQoLAssess qualityDiseaseCirrhosisSignificant differencesScoresP13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of life
Camarata M, Ala A, Maciejewski K, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Coskun A, Apdik T, Tomlin R, Deng Y, Schilsky M. P13 Major depressive disorder in patients with wilson’s disease: relationship with liver disease, neurological disease and quality of life. Gut 2020, 69: a13-a13. DOI: 10.1136/gutjnl-2020-basl.24.Peer-Reviewed Original ResearchMajor depressive disorderQuality of lifeMental health QOLWilson's diseaseNeurological diseasesLiver diseaseDepressive disorderFirst presentationExact testDepression symptomologySeverity of liverLifetime major depressive disorderLiver disease severityFisher's exact testPhysical health QOLSignificant differencesWilcoxon rank sum testMental health problemsRank sum testFIB4 scoreClinical featuresNeurological assessmentPHQ-9PatientsCurrent depressionFRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life
Camarata M, Ala A, To U, Zimbrean P, Rubman S, Patel A, Wadhwa A, Maciejewski K, Song X, Deng Y, Tomlin R, Apdik T, Coskun A, Schilsky M. FRI303 Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life. Journal Of Hepatology 2020, 73: s550-s551. DOI: 10.1016/s0168-8278(20)31573-7.Peer-Reviewed Original ResearchSystematic Review: Treatment for Addictive Disorder in Transplant Patients
Luchsinger W, Zimbrean P. Systematic Review: Treatment for Addictive Disorder in Transplant Patients. American Journal On Addictions 2020, 29: 445-462. PMID: 32410396, DOI: 10.1111/ajad.13054.Peer-Reviewed Original ResearchConceptsTransplant patientsAlcohol use disorderUse disordersOrgan transplantationAddictive disordersSystematic reviewLiver transplant patientsOpioid use disorderNumber of patientsPromising treatment optionSubstance use disordersOpioid disordersFirst systematic reviewTransplant candidatesHeart transplantTreatment optionsCase reportOutcome measuresMedical statusHigh riskPatientsDatabases PubMedTreatment interventionsControl groupLiterature search
2019
Implementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial
Martino S, Zimbrean P, Forray A, Kaufman JS, Desan PH, Olmstead TA, Gilstad-Hayden K, Gueorguieva R, Yonkers KA. Implementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial. Journal Of General Internal Medicine 2019, 34: 2520-2529. PMID: 31468342, PMCID: PMC6848470, DOI: 10.1007/s11606-019-05257-3.Peer-Reviewed Original ResearchConceptsConsultation-liaison serviceSubstance misuseMotivational interviewMedical inpatientsGeneral medical inpatient servicesMedical inpatient servicesGeneral medical inpatientsStudy-eligible patientsMedical inpatient unitsAcute care hospitalsMain MeasuresPrimary outcomesMedical education workshopSecondary outcomesCare hospitalControlled TrialsEffective implementation strategiesMeasuresPrimary outcomesMedical HospitalInpatient unitInpatient servicesMedical ordersPatientsPatients' statementsMotivational interviewingInpatientsBody Image in Liver Transplantation Recipients
Zimbrean PC, Gan G, Deng Y, Emre S. Body Image in Liver Transplantation Recipients. Liver Transplantation 2019, 25: 712-723. PMID: 30746848, DOI: 10.1002/lt.25432.Peer-Reviewed Original ResearchConceptsLiver transplant recipientsTransplant recipientsQuality of lifeBI concernsLiver transplantation recipientsChronic liver diseaseAcute liver failureCross-sectional studyMental health carePaucity of dataLiver transplantationTransplantation recipientsYounger patientsLiver failureLiver diseaseQOL scoresOrgan transplantationPatientsRecipientsHealth careBody image concernsTransplantationLow incomeBody imageDepressionChapter 19 Wilson Disease Psychiatric Aspects
Zimbrean P. Chapter 19 Wilson Disease Psychiatric Aspects. 2019, 215-225. DOI: 10.1016/b978-0-12-810532-0.00019-7.Peer-Reviewed Original ResearchQuality of lifeWilson's diseasePsychiatric presentationsGoals of careNewer psychotropic medicationsIrreversible cognitive declineCommon presentationNeurological findingsSymptomatic treatmentPsychotropic medicationsCurrent treatmentGeneral populationPsychiatric aspectsCognitive declineFunctional psychosesWD patientsCognitive deficitsMood instabilitySymptomsTreatmentPresentationSecondary effectsRemissionMedicationsPatients
2018
The Role of the Psychiatrist in the Perioperative Setting
Zimbrean P. The Role of the Psychiatrist in the Perioperative Setting. 2018, 7-14. DOI: 10.1007/978-3-319-99774-2_2.Peer-Reviewed Original ResearchPerioperative settingPsychiatric servicesCommon psychiatric presentationsGeneral hospital settingCare of patientsConsultation-liaison psychiatrySurgical outcomesPsychiatric presentationsGeneral HospitalPsychiatric illnessHospital settingConsultation modelPsychiatric subspecialtySettingPsychiatryPatientsSurgeryHospitalIllnessCarePerioperative Psychiatric Aspects in Neurosurgery
Munjal S, Zimbrean P. Perioperative Psychiatric Aspects in Neurosurgery. 2018, 145-171. DOI: 10.1007/978-3-319-99774-2_10.Peer-Reviewed Original ResearchComorbid neurological conditionsPerioperative psychiatric symptomsTraumatic brain injuryCommon neurosurgical procedurePsychotropic medicationsNeurosurgical treatmentPsychiatric presentationsBrain injuryNeurosurgical interventionPerioperative settingNeurological conditionsPsychiatric symptomsNeurosurgical conditionsPsychiatric assessmentBrain tumorsPsychiatric aspectsPsychiatric conditionsNeurosurgical proceduresPsychoactive effectsMedicationsSymptomsPatientsEpilepsyInjuryTumorsMental Health in Chronic and End-Stage Renal Disease
Zimbrean P, Braverman J, Novak M. Mental Health in Chronic and End-Stage Renal Disease. 2018, 73-89. DOI: 10.1007/978-3-319-94914-7_6.Peer-Reviewed Original ResearchChronic kidney diseaseRenal replacement therapyReplacement therapyPsychiatric presentationsEnd-stage renal diseaseCommon mental health concernsCommon psychiatric presentationsMental health presentationsMental health concernsMental health considerationsRenal diseaseCardiovascular changesKidney diseaseDepressive disorderHealth presentationsHigh prevalenceSleep disordersUS adultsPsychiatric concernsPatientsPsychiatric conditionsAge 20Disease controlHealth concernMental healthDialysis: Medical and Psychological Considerations
Hussain F, Zimbrean P. Dialysis: Medical and Psychological Considerations. 2018, 91-102. DOI: 10.1007/978-3-319-94914-7_7.Peer-Reviewed Original ResearchEnd-stage renal diseaseChronic kidney diseaseStage 5 chronic kidney diseaseDiscontinuation of dialysisRenal replacement modalityAge-matched cohortDemand of dialysisRenal diseasePeritoneal dialysisReplacement modalityCenter hemodialysisKidney diseasePatient populationWorse outcomesSleep disordersGeneral populationMortality rateRelevant pharmacologyHome dialysisPsychiatric implicationsMedical considerationsPatientsDialysisIncreased ratesDisease