2011
Progesterone enhances adrenergic control of skin blood flow in women with high but not low orthostatic tolerance
Wenner MM, Taylor HS, Stachenfeld NS. Progesterone enhances adrenergic control of skin blood flow in women with high but not low orthostatic tolerance. The Journal Of Physiology 2011, 589: 975-986. PMID: 21173076, PMCID: PMC3060374, DOI: 10.1113/jphysiol.2010.194563.Peer-Reviewed Original ResearchConceptsLow orthostatic toleranceHigh orthostatic toleranceOrthostatic toleranceAdrenergic responseAdrenergic responsivenessNitric oxide synthase inhibitor NG-monomethylEndogenous sex hormone productionSynthase inhibitor NG-monomethylSkin blood flow responseBlood flow responseInhibitor NG-monomethylSex hormone productionFemale sex hormonesLower body negative pressure testSkin blood flowGnRH antagonistProgesterone administrationOrthostatic intoleranceNG-monomethylPeripheral αMicrodialysis infusionSex hormonesCyclooxygenase pathwayHT womenAdrenergic control
2010
Greater Orthostatic Tolerance in Young Black Compared With White Women
Hinds K, Stachenfeld NS. Greater Orthostatic Tolerance in Young Black Compared With White Women. Hypertension 2010, 56: 75-81. PMID: 20458005, PMCID: PMC2909588, DOI: 10.1161/hypertensionaha.110.150011.Peer-Reviewed Original ResearchConceptsLower body negative pressureBody negative pressureOrthostatic toleranceWhite womenHeart rateGreater sympathetic nervous system responseR intervalSympathetic nervous system responsesPlasma renin activityPlasma catecholamine concentrationsSerum aldosterone concentrationNervous system responsesNegative pressureBlack womenCumulative stress indexWoman underwentRenin activityAldosterone concentrationBaroreflex functionBlood pressureCatecholamine concentrationsOrthostatic challengePlasma concentrationsHealthy blacksBlood samples