2024
Cervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success
Galecio-Castillo M, Guerrero W, Hassan A, Farooqui M, Jumaa M, Divani A, Abraham M, Petersen N, Fifi J, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Olivé-Gadea M, Tekle W, Zaidi S, Sabbagh S, Barkley T, Prasad A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Dibas M, Mokin M, Yavagal D, Ribo M, Jovin T, Ortega-Gutierrez S. Cervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success. Stroke 2024, 55: 1808-1817. PMID: 38913799, DOI: 10.1161/strokeaha.123.046148.Peer-Reviewed Original ResearchConceptsInternal carotid arteryCervical internal carotid arteryDistal embolizationModified ThrombolysisTandem lesionsMulticenter retrospective cohort studyParenchymal hematoma type 2Internal carotid artery stenosis/occlusionModified Rankin Scale scoreSymptomatic intracranial hemorrhageInverse probability of treatment weightingCerebral Infarction scoreCervical ICA dissectionRetrospective cohort studyProbability of treatment weightingRankin Scale scoreAssociated with higher ratesFunctional independenceRates of hypertensionAssociated with distal embolizationSelf-expanding stentsDissection etiologyRisk of distal embolizationICA occlusionCervical dissectionDeviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization
Zhang Z, Pu Y, Yu L, Bai H, Duan W, Liu X, Nie X, Wen Z, Zheng L, Hu X, Leng X, Pan Y, Petersen N, Liu L. Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization. Journal Of The American Heart Association 2024, 13: e033633. PMID: 38533955, PMCID: PMC11179781, DOI: 10.1161/jaha.123.033633.Peer-Reviewed Original ResearchConceptsBlood pressure targetsBlood pressureAutoregulatory limitsWorse outcomesAssociated with symptomatic intracranial hemorrhageAssociated with unfavorable clinical outcomesPressure targetsAssociated with worse outcomesAssociated with poor outcomesSignificant infarction growthSymptomatic intracranial hemorrhageUnfavorable clinical outcomeLarge vessel occlusion strokeAcute ischemic strokeMean velocity indexIntracranial hemorrhageBP management strategiesNeurological deteriorationClinical outcomesInfarct growthPoor outcomeEndovascular thrombectomyOcclusion strokeRecanalizationIschemic strokeAnesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions
Farooqui M, Galecio-Castillo M, Hassan A, Divani A, Jumaa M, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Sabbagh S, Zaidi S, Gadea M, Prasad A, Qureshi A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Anesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions. Journal Of NeuroInterventional Surgery 2024, jnis-2023-021360. PMID: 38429099, DOI: 10.1136/jnis-2023-021360.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageModified Rankin scoreFavorable functional outcomeAlberta Stroke Program Early CT ScoreNational Institutes of Health Stroke ScaleEndovascular therapyInternal carotid arteryFunctional outcomesAcute ischemic strokeProcedural sedationExcellent recanalizationTandem lesionsAssociated with superior functional outcomesBaseline Alberta Stroke Program Early CT ScoreAnesthetic strategyRecanalization timeAnterior circulation tandem lesionsGeneral anesthesiaAnesthetic techniqueDegree of internal carotid arteryInternal carotid artery stentingOptimal anesthetic strategyIschemic strokeLarge vessel occlusion acute ischemic strokeAcute ischemic stroke patients
2023
Safety of Intravenous Cangrelor Versus Dual Oral Antiplatelet Loading Therapy in Endovascular Treatment of Tandem Lesions: An Observational Cohort Study
Rodriguez‐Calienes A, Oliver M, Hassan A, Vivanco‐Suarez J, Divani A, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe‐Orozco D, Galecio‐Castillo M, Alhajala H, Malaga M, Farooqui M, Jovin T, Jumaa M, Ortega‐Gutierrez S. Safety of Intravenous Cangrelor Versus Dual Oral Antiplatelet Loading Therapy in Endovascular Treatment of Tandem Lesions: An Observational Cohort Study. Stroke Vascular And Interventional Neurology 2023, 3 DOI: 10.1161/svin.123.001020.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageIntravenous cangrelorIntracranial hemorrhageStent thrombosisSafety profilePetechial hemorrhagesTandem lesionsType 2Parenchymal hematoma type 2Inverse probabilityInternational multicenter cohortSimilar safety profileAcute ischemic strokeObservational cohort studyMyocardial infarction protocolDAPT regimensIntraprocedural administrationLoading therapyAntiplatelet therapyCohort studyIschemic strokeLesion interventionMulticenter cohortEndovascular treatmentInfarction protocolsMechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study.
Rodriguez-Calienes A, Hassan A, Siegler J, Galecio-Castillo M, Farooqui M, Jumaa M, Janjua N, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Nguyen T, Sheth S, Yoo A, Linares G, Lu Y, Vivanco-Suarez J, Ortega-Gutierrez S. Mechanical thrombectomy beyond 24 hours from last known well in tandem lesions: A multicenter cohort study. Interventional Neuroradiology 2023, 15910199231196960. PMID: 37642978, DOI: 10.1177/15910199231196960.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageNIH Stroke ScaleMechanical thrombectomyHospital mortalityComplete reperfusionTandem lesionsFunctional independenceAnterior circulation tandem lesionsEffectiveness of MTMulticenter cohort studyLarge vessel occlusionFuture prospective studiesTreatment of patientsOutcomes of interestMulticenter registryStroke ScaleCohort studyIntracranial hemorrhageProspective studyVessel occlusionHematoma 2Treatment weightingPatientsInverse probabilityMortalityClinical and Safety Outcomes of Endovascular Therapy 6 to 24 Hours After Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
Galecio-Castillo M, Farooqui M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Zaidi S, Sabbagh S, Olivé-Gadea M, Barkley T, De Leacy R, Sprankle K, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Vivanco-Suarez J, Rodriguez-Calienes A, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Clinical and Safety Outcomes of Endovascular Therapy 6 to 24 Hours After Large Vessel Occlusion Ischemic Stroke With Tandem Lesions. Journal Of Stroke 2023, 25: 378-387. PMID: 37607694, PMCID: PMC10574302, DOI: 10.5853/jos.2023.00759.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageSafety outcomesMRS 0Secondary outcomesEndovascular therapyTandem lesionsLarge vessel occlusion ischemic strokeLower median National InstitutesHealth Stroke Scale scoreLarge vessel occlusion patientsEarly neurological improvementMedian National InstitutesStroke Scale scoreAlberta Stroke ProgramModified Rankin ScaleFirst-pass effectEarly windowIntravenous thrombolysisOrdinal mRSNeurological improvementSuccessful reperfusionTomography ScoreIschemic strokeRankin ScaleStroke ProgramSafety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions
Rodriguez-Calienes A, Galecio-Castillo M, Farooqui M, Hassan A, Jumaa M, Divani A, Ribo M, Abraham M, Petersen N, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Alhajala H, Ikram A, Rizzo F, Qureshi A, Begunova L, Matsoukas S, Vigilante N, Salazar-Marioni S, Abdalkader M, Gordon W, Soomro J, Turabova C, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Sheth S, Ortega-Gutierrez S. Safety Outcomes of Mechanical Thrombectomy Versus Combined Thrombectomy and Intravenous Thrombolysis in Tandem Lesions. Stroke 2023, 54: 2522-2533. PMID: 37602387, PMCID: PMC10599264, DOI: 10.1161/strokeaha.123.042966.Peer-Reviewed Original ResearchConceptsRisk of sICHParenchymal hematoma type 2Symptomatic intracranial hemorrhageRankin Scale score 0Intravenous antiplatelet therapyIntravenous thrombolysisFavorable functional outcomeMechanical thrombectomyHemorrhagic transformationFunctional outcomeType 2Antiplatelet therapyHospital mortalitySuccessful reperfusionComplete reperfusionScore 0Tandem lesionsAnterior circulation tandem lesionsExcellent functional outcomeIVT treatmentStroke centersMulticenter cohortPrimary outcomeRevascularization techniquesAlone group