2024
Shaping childhood obesity: behavioral and environmental risk factors associated with body mass index trajectories between 2 and 9 years in Samoan children
Choy C, Johnson W, Naseri T, Filipo V, Arorae M, Tafunaina F, Unasa F, Savusa K, Reupena M, Braun J, Duckham R, Soti-Ulberg C, McGarvey S, Hawley N. Shaping childhood obesity: behavioral and environmental risk factors associated with body mass index trajectories between 2 and 9 years in Samoan children. International Journal Of Obesity 2024, 1-10. PMID: 39472691, DOI: 10.1038/s41366-024-01665-6.Peer-Reviewed Original ResearchBody mass indexDietary pattern adherenceHigher body mass indexPhysical activityNetherlands Physical Activity QuestionnaireRisk factorsBody mass index trajectoriesFood frequency questionnaire dataPhysical Activity QuestionnaireHigh physical activityBody mass index gainBehavioral risk factorsHousehold asset scoreLow household assetsCubic spline regressionAged 2 to 4 yearsAged 2Public health solutionsChildhood risk factorsSamoan childrenActivity QuestionnaireObesity preventionBMI trajectoriesObesity riskHealth solutionsAssociations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Rivara A, Russell E, Carlson J, Pomer A, Naseri T, Reupena M, Manna S, Viali S, Minster R, Weeks D, DeLany J, Kershaw E, McGarvey S, Hawley N. Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort. PLOS ONE 2024, 19: e0302643. PMID: 38829901, PMCID: PMC11146712, DOI: 10.1371/journal.pone.0302643.Peer-Reviewed Original ResearchConceptsType 2 diabetesAllele of rs373863828Body mass indexFasting glucoseAdult SamoansDevelopment of type 2 diabetesOdds of type 2 diabetesReduction of modifiable risk factorsRs373863828 genotypeAssociated with higher body mass indexType 2 diabetes developmentGlucose rate of changeMass indexHousehold asset scoreUrbanization of residenceHigher body mass indexRisk factorsModifiable risk factorsRate of changeBaseline variablesMultivariate linear regressionPhysical activityDiabetes preventionType 2 diabetes mellitusSmoking statusAssociations of childhood BMI traits with blood pressure and glycated haemoglobin in 6–9‐year‐old Samoan children
Choy C, Johnson W, Braun J, Soti‐Ulberg C, Reupena M, Naseri T, Savusa K, Lupematasila V, Arorae M, Tafunaina F, Unasa F, Duckham R, Wang D, McGarvey S, Hawley N. Associations of childhood BMI traits with blood pressure and glycated haemoglobin in 6–9‐year‐old Samoan children. Pediatric Obesity 2024, 19: e13112. PMID: 38439600, PMCID: PMC11081844, DOI: 10.1111/ijpo.13112.Peer-Reviewed Original ResearchBody mass indexBody mass index velocityBody mass index trajectoriesChildhood BMI trajectoriesBlood pressureHigher body mass indexChildhood characteristicsAssociation of HbA1cAssociated with higher BPAt-risk populationsSamoan childrenGlycated hemoglobinBMI trajectoriesPacific childrenPrevention effortsCohort studyElevated glycated hemoglobinHigher HbA1cMass indexHigh BPElevated BPYear oldsAt-riskMultilevel modelsRisk factors
2023
Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations
Krishnan M, Phipps-Green A, Russell E, Major T, Cadzow M, Stamp L, Dalbeth N, Hindmarsh J, Qasim M, Watson H, Liu S, Carlson J, Minster R, Hawley N, Naseri T, Reupena M, Deka R, McGarvey S, Merriman T, Murphy R, Weeks D. Association of rs9939609 in FTO with BMI among Polynesian peoples living in Aotearoa New Zealand and other Pacific nations. Journal Of Human Genetics 2023, 68: 463-468. PMID: 36864286, PMCID: PMC10313811, DOI: 10.1038/s10038-023-01141-5.Peer-Reviewed Original ResearchConceptsBody mass indexMean body mass indexHigher body mass indexPrevious smaller studiesAssociation of rs9939609New Zealand PolynesiansMass indexFat massSmall studySignificant associationPolynesian ancestryFTO variantsRs9939609Effect size estimatesAssociationSimilar effectsMean effect size estimate
2022
CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand
Russell EM, Carlson JC, Krishnan M, Hawley NL, Sun G, Cheng H, Naseri T, Reupena M, Viali S, Tuitele J, Major TJ, Miljkovic I, Merriman TR, Deka R, Weeks DE, McGarvey ST, Minster RL. CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand. BMJ Open Diabetes Research & Care 2022, 10: e002275. PMID: 35144939, PMCID: PMC8845200, DOI: 10.1136/bmjdrc-2021-002275.Peer-Reviewed Original ResearchConceptsBody mass indexType 2 diabetesAssociation of BMIHigher body mass indexMinor alleleType 2 diabetes riskCross-sectional associationsPacific Island populationsRs373863828 genotypeMass indexDiabetes riskHigher oddsLower oddsDiabetesObesityEvidence of differencesMissense variantsRs373863828Regression analysisGlucoseAssociationOddsIndirect effectsPolynesian individuals