2024
Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study
Shimbo D, Cohen M, McGoldrick M, Ensari I, Diaz K, Fu J, Duran A, Zhao S, Suls J, Burg M, Chaplin W. Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study. Journal Of The American Heart Association 2024, 13: e032698. PMID: 38690710, PMCID: PMC11179860, DOI: 10.1161/jaha.123.032698.Peer-Reviewed Original ResearchConceptsEndothelial cell-derived microparticlesEndothelium-dependent vasodilationCell-derived microparticlesEndothelial progenitor cellsGroup x time interactionEndothelial cell healthCirculating bone marrow-derived endothelial progenitor cellsIncreased risk of cardiovascular disease eventsIndex scoreEndothelial healthProgenitor cellsImpaired endothelium-dependent vasodilationRisk of cardiovascular disease eventsAcute effectsTime interactionBone marrow-derived endothelial progenitor cellsMarrow-derived endothelial progenitor cellsRecall taskStatistically significant group x time interactionsSignificant group x time interactionRandomized controlled studyCardiovascular disease eventsVascular endothelial healthRandomized controlled experimental studyNegative emotions
2012
Endothelial cell activation, reduced endothelial cell reparative capacity, and impaired endothelial-dependent vasodilation after anger provocation
Shimbo D, Rosenberg LB, Chaplin W, Zhao S, Goldensohn ER, Cholankeril M, Fu J, Hong SB, Jelic S, Burg MM. Endothelial cell activation, reduced endothelial cell reparative capacity, and impaired endothelial-dependent vasodilation after anger provocation. International Journal Of Cardiology 2012, 167: 1064-1065. PMID: 23157814, PMCID: PMC3582854, DOI: 10.1016/j.ijcard.2012.10.069.Peer-Reviewed Original Research
2011
Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease
Burg MM, Soufer A, Lampert R, Collins D, Soufer R. Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease. Molecular Medicine 2011, 17: 495-501. PMID: 21267513, PMCID: PMC3105151, DOI: 10.2119/molmed.2010.00083.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Parasympathetic activityArtery diseaseAutonomic contributionsChronic stable coronary artery diseaseStable coronary artery diseaseCholinergic antiinflammatory pathwayLaboratory stressCoronary plaque ruptureEndothelin-1 increaseSignificant odds ratioEndothelial cell functionCardiac eventsEndothelial dysfunctionIndwelling catheterAutonomic factorsSympathetic activityAntiinflammatory pathwayAutonomic influencesAutonomic toneOdds ratioPlaque ruptureParasympathetic withdrawalHemodynamic monitor
2010
Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease
Fernandez AB, Soufer R, Collins D, Soufer A, Ranjbaran H, Burg MM. Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease. Psychosomatic Medicine 2010, 72: 348-353. PMID: 20368479, PMCID: PMC2872076, DOI: 10.1097/psy.0b013e3181d71982.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseET-1 increaseET-1Chronic stable coronary heart diseaseStable coronary heart diseaseMultivariate logistic regression modelET-1 elevationAcute coronary syndromeHistory of diabetesRate-pressure productCoronary artery diseaseEndothelin-1 increaseLogistic regression modelsCoronary syndromeArtery diseaseBeta blockersPotential confoundersPressure productHeart diseasePlaque ruptureBlood samplesPatientsAngry ruminationNitric oxideStress protocol