2019
In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation
Davis MT, Hillmer A, Holmes SE, Pietrzak RH, DellaGioia N, Nabulsi N, Matuskey D, Angarita G, Carson RE, Krystal JH, Esterlis I. In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 11490-11495. PMID: 31085640, PMCID: PMC6561298, DOI: 10.1073/pnas.1818871116.Peer-Reviewed Original ResearchConceptsMGluR5 availabilitySuicidal ideationHC individualsPathophysiology of PTSDLimbic brain regionsVolume of distributionHealthy comparison controlsSuicide risk managementPositron emission tomographyReceptor 5Venous input functionsBrain regionsPTSD individualsEmission tomographyMDD individualsVivo evidenceRecent evidencePotential roleMGluR5PTSDComparison controlsDysregulationMDDIdeationIndividuals
2016
Longitudinal suicidal ideation across 18-months postpartum in mothers with childhood maltreatment histories
Muzik M, Brier Z, Menke RA, Davis MT, Sexton MB. Longitudinal suicidal ideation across 18-months postpartum in mothers with childhood maltreatment histories. Journal Of Affective Disorders 2016, 204: 138-145. PMID: 27344623, PMCID: PMC5012909, DOI: 10.1016/j.jad.2016.06.037.Peer-Reviewed Original ResearchConceptsPostpartum suicidal ideationSuicidal ideationChildhood maltreatmentProtective factorsCM historyMaternal suicidal ideationSeverity of SIHistory of CMSample of womenChildhood maltreatment historyPostpartumFactor associationsPercentage countsMarital statusSeverityMothersRiskIdeationFamily supportHigh rateSelf-report measuresMaltreatment historyNon-clinical sampleWomenAssociation