2019
Monitoring neurocognitive functioning in childhood cancer survivors: evaluation of CogState computerized assessment and the Behavior Rating Inventory of Executive Function (BRIEF)
Balsamo LM, Mitchell HR, Ross W, Metayer C, Hardy KK, Kadan-Lottick NS. Monitoring neurocognitive functioning in childhood cancer survivors: evaluation of CogState computerized assessment and the Behavior Rating Inventory of Executive Function (BRIEF). BMC Psychology 2019, 7: 26. PMID: 31046815, PMCID: PMC6498488, DOI: 10.1186/s40359-019-0302-3.Peer-Reviewed Original ResearchConceptsBehavior Rating InventoryFull neuropsychological evaluationRating InventoryNeuropsychological evaluationChildhood cancer survivorsGrade-level performanceComprehensive neuropsychological testingCancer survivorsExecutive functionNeurocognitive functioningPsychosocial functioningAcademic difficultiesNeuropsychological testingComputerized assessmentNeurocognitive impairmentNeed of evaluationFunctioningReadingImproving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach
Balsamo L, Shabanova V, Carbonella J, Szondy MV, Kalbfeld K, Thomas DA, Santucci K, Grossman M, Pashankar F. Improving Care for Sickle Cell Pain Crisis Using a Multidisciplinary Approach. Pediatrics 2019, 143: e20182218. PMID: 30944154, DOI: 10.1542/peds.2018-2218.Peer-Reviewed Original ResearchConceptsVaso-occlusive crisisHospital daysReadmission ratesHospital costsSickle cell disease vaso-occlusive crisisMultidisciplinary quality improvement projectSickle cell pain crisisThirty-day readmission ratesDedicated team effortSCD pediatric patientsPatients ages 0Direct hospital costsLength of stayHigh usersStudy-Act methodologyQuality improvement projectMental health providersHigh-use groupPain planPain crisisFrequent hospitalizationsRisk patientsPediatric patientsPreintervention periodEmergency department
2018
Parental perception of child vulnerability in childhood cancer survivors
Hogan M, Ross WL, Balsamo L, Mitchell H, Kadan‐Lottick N. Parental perception of child vulnerability in childhood cancer survivors. Pediatric Blood & Cancer 2018, 65: e27364. PMID: 30024087, DOI: 10.1002/pbc.27364.Peer-Reviewed Original ResearchConceptsChildhood cancer survivorsCancer survivorsLate complicationsCancer historyPercent of parentsCurrent health statusCurrent mean ageChild Vulnerability ScalePatient sociodemographicsClinic visitsCohort studySurvivorship clinicPediatric patientsTherapy completionYears posttherapyMean ageMedical recordsLower riskHealth statusComplicationsChild vulnerabilityCancer treatmentSurvivorsTreatment intensityCancer diagnosisLong‐term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study
Zheng DJ, Krull KR, Chen Y, Diller L, Yasui Y, Leisenring W, Brouwers P, Howell R, Lai J, Balsamo L, Oeffinger KC, Robison LL, Armstrong GT, Kadan‐Lottick N. Long‐term psychological and educational outcomes for survivors of neuroblastoma: A report from the Childhood Cancer Survivor Study. Cancer 2018, 124: 3220-3230. PMID: 29888538, PMCID: PMC6168938, DOI: 10.1002/cncr.31379.Peer-Reviewed Original ResearchConceptsBehavior Problem IndexPsychological impairmentChronic health conditionsNeuroblastoma survivorsElevated riskAdult educational attainmentMultivariate log-binomial modelsMore chronic health conditionsPrevalence of impairmentPsychological functioningHealth conditionsAttention deficitsChildhood cancer survivorsAntisocial behaviorHigh-risk groupAnxiety/depressionEducational attainmentSocial withdrawalLog-binomial modelsNeurotoxic treatmentMedian agePeripheral neuropathyYear survivorsPulmonary diseaseCancer survivors
2017
Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial
Zheng DJ, Lu X, Schore RJ, Balsamo L, Devidas M, Winick NJ, Raetz EA, Loh ML, Carroll WL, Sung L, Hunger SP, Angiolillo AL, Kadan‐Lottick N. Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial. Cancer 2017, 124: 571-579. PMID: 29112230, PMCID: PMC5808870, DOI: 10.1002/cncr.31085.Peer-Reviewed Original ResearchConceptsAverage-risk acute lymphoblastic leukemiaQuality of lifeEmotional impairmentsLife Inventory (PedsQL) Generic CoreHigh-risk patientsProspective cohort studyTime of diagnosisEnd of therapyAcute lymphoblastic leukemiaFamily-based interventionsCohort studyQoL impairmentMean ageLymphoblastic leukemiaQOL outcomesPediatric QualityProportion of individualsEarly screeningPopulation normsImpaired rangeImpairmentMonthsTime pointsFunctioning impairmentImpairment patterns
2016
Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study
Kunin-Batson AS, Lu X, Balsamo L, Graber K, Devidas M, Hunger SP, Carroll WL, Winick NJ, Mattano LA, Maloney KW, Kadan-Lottick NS. Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study. Cancer 2016, 122: 1608-1617. PMID: 27028090, PMCID: PMC4860039, DOI: 10.1002/cncr.29946.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaCompletion of treatmentGreater riskEmotional-behavioral functioningChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaAdjusted longitudinal analysesCompletion of chemotherapyDepressive symptoms 6 monthsSymptoms 6 monthsEmotional distressElevated anxiety scoresAnxiety 1 monthStandardized rating scalesElevated depression scoresChildren's emotional-behavioral functioningLymphoblastic leukemiaPredictors of anxietySocial support copingMeasures of copingDepressive symptomsGeneral populationDepression scoresPsychosocial interventionsEarly screening
2015
The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia
Balsamo LM, Sint KJ, Neglia JP, Brouwers P, Kadan-Lottick NS. The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia. Journal Of Pediatric Psychology 2015, 41: 319-328. PMID: 26514641, PMCID: PMC4852216, DOI: 10.1093/jpepsy/jsv103.Peer-Reviewed Original ResearchConceptsFine motorLeukemia survivorsPediatric acute lymphoblastic leukemia survivorsAcute lymphoblastic leukemia survivorsAcute lymphoblastic leukemiaCross-sectional studyVisual-motor integration skillsFirst remissionPediatric survivorsLymphoblastic leukemiaEffect modificationSurvivorsMotor skillsFM skillsAssociationLow intelligenceRemissionLeukemiaIntegration skillsYearsProspective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331
Mitchell H, Lu X, Myers RM, Sung L, Balsamo LM, Carroll WL, Raetz E, Loh ML, Mattano LA, Winick NJ, Devidas M, Hunger SP, Maloney K, Kadan-Lottick N. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331. International Journal Of Cancer 2015, 138: 332-339. PMID: 26235006, PMCID: PMC5138856, DOI: 10.1002/ijc.29708.Peer-Reviewed Original ResearchConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLife Inventory 4.0 Generic Core ScalesChildren's Oncology Group studyHRQoL 1 monthMean PedsQL scoresYears of therapyHealth-related qualityEnd of inductionHigh cure ratesGeneric Core ScalesSocial functioningRepeated-measures analysisTherapy completionTherapeutic trialsCure ratePediatric QualityPedsQL scoresConsiderable impairmentLongitudinal assessmentDiagnosisTherapyMonthsGroup study
2014
Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report
Lau S, Lu X, Balsamo L, Devidas M, Winick N, Hunger SP, Carroll W, Stork L, Maloney K, Kadan‐Lottick N. Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report. Pediatric Blood & Cancer 2014, 61: 2277-2284. PMID: 25175168, PMCID: PMC4282930, DOI: 10.1002/pbc.25195.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaChildren's Oncology Group reportChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemia therapyMonths of therapyProspective cohort studyAppropriate anticipatory guidanceHigh cure ratesLong-term outcomesMore childrenHealth care providersLess maternal educationFirst yearCohort studyPatient factorsCure rateLymphoblastic leukemiaCOG protocolsCare providersAnticipatory guidanceEligibility criteriaHigh incidenceLeukemia therapyMaternal educationAverage riskA prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia
Myers RM, Balsamo L, Lu X, Devidas M, Hunger SP, Carroll WL, Winick NJ, Maloney KW, Kadan‐Lottick N. A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia. Cancer 2014, 120: 1417-1425. PMID: 24473774, PMCID: PMC4319360, DOI: 10.1002/cncr.28578.Peer-Reviewed Original ResearchMeSH KeywordsAggressionAntineoplastic Combined Chemotherapy ProtocolsAnxietyAsparaginaseBehaviorChildChild, PreschoolCohort StudiesCyclophosphamideDepressionDexamethasoneEmotionsFemaleHumansLongitudinal StudiesMalePolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesPsychomotor AgitationVincristineConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaUnhealthy family functioningHispanic ethnicityChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaClinical rangeSubpopulation of patientsWorse physical functioningMore childrenFirst yearCoping Health InventoryCohort studyProspective studyRisk factorsPhysical functioningFamily functioningHealth InventoryFamily Assessment DevicePopulation normsMonthsFunctioning ScaleDepressionGroup protocol
2010
OBSERVING BEHAVIOR AND ATYPICALLY RESTRICTED STIMULUS CONTROL
Dube WV, Dickson CA, Balsamo LM, O'Donnell KL, Tomanari GY, Farren KM, Wheeler EE, McIlvane WJ. OBSERVING BEHAVIOR AND ATYPICALLY RESTRICTED STIMULUS CONTROL. Journal Of The Experimental Analysis Of Behavior 2010, 94: 297-313. PMID: 21541173, PMCID: PMC2972782, DOI: 10.1901/jeab.2010.94-297.Peer-Reviewed Original ResearchConceptsStimulus controlSample stimuliIntellectual disabilityAccuracy scoresEye-tracking apparatusEye-tracking dataEye tracking dataStimulus featuresHigher accuracy scoresApparent instanceStimuliCapable individualsParticipantsContingenciesInterventionAtypicallyTracking dataIndividualsBehaviorScoresAdditional interventionsObservingDiscriminationTwo-sampleDisability
2006
Language lateralization and the role of the fusiform gyrus in semantic processing in young children
Balsamo LM, Xu B, Gaillard WD. Language lateralization and the role of the fusiform gyrus in semantic processing in young children. NeuroImage 2006, 31: 1306-1314. PMID: 16545581, DOI: 10.1016/j.neuroimage.2006.01.027.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBrain MappingCerebral CortexChildChild, PreschoolDecision MakingDominance, CerebralFemaleFrontal LobeHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMotor CortexNeuropsychological TestsOxygenPsychomotor PerformanceReaction TimeReadingSemanticsSpeech PerceptionConceptsSemantic processingFusiform gyrusEarly word recognition processesAuditory semantic processingWord recognition processesAdult language processingSemantic decision taskSemantic category decisionsLeft fusiform gyrusPrevious neuroimaging findingsLeft-lateralized patternYoung childrenPattern of activationLanguage comprehensionDecision taskCategory decisionsTask accuracyTask difficultyLanguage developmentLanguage lateralizationFMRI techniquesLanguage processingBrain regionsCortical regionsNeuroimaging findings
2005
Seizure focus affects regional language networks assessed by fMRI
Berl MM, Balsamo LM, Xu B, Moore EN, Weinstein SL, Conry JA, Pearl PL, Sachs BC, Grandin CB, Frattali C, Ritter FJ, Sato S, Theodore WH, Gaillard WD. Seizure focus affects regional language networks assessed by fMRI. Neurology 2005, 65: 1604-1611. PMID: 16301489, DOI: 10.1212/01.wnl.0000184502.06647.28.Peer-Reviewed Original ResearchConceptsRegional asymmetry index
2004
fMRI language task panel improves determination of language dominance
Gaillard WD, Balsamo L, Xu B, McKinney C, Papero PH, Weinstein S, Conry J, Pearl PL, Sachs B, Sato S, Vezina LG, Frattali C, Theodore WH. fMRI language task panel improves determination of language dominance. Neurology 2004, 63: 1403-1408. PMID: 15505156, DOI: 10.1212/01.wnl.0000141852.65175.a7.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingCerebral CortexCerebrovascular CirculationChildDominance, CerebralEpilepsyFemaleHumansLanguageLanguage TestsMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsPreoperative CareReproducibility of ResultsSpeech PerceptionTemporal LobeVerbal BehaviorConceptsIntracarotid amobarbital testPanel of tasksLanguage dominanceSingle taskEpilepsy patientsFMRI language paradigmsHemisphere language dominancePatients ages 12Temporal lobe epilepsyPartial epilepsy patientsPresurgical epilepsy patientsAuditory comprehensionFMRI taskVerbal fluencyLanguage tasksLanguage lateralityBilateral activationLanguage lateralizationT fMRILanguage areasNondiagnostic findingsLobe epilepsyAmobarbital testLanguage paradigmsSingle paradigm
2003
Auditory comprehension of language in young children
Ahmad Z, Balsamo L, Sachs B, Xu B, Gaillard W. Auditory comprehension of language in young children. Neurology 2003, 60: 1598-1605. PMID: 12771248, DOI: 10.1212/01.wnl.0000059865.32155.86.Peer-Reviewed Original ResearchConceptsAuditory comprehensionTemporal gyrusYoung childrenLeft middle temporal gyrusAuditory language processingSuperior temporal sulcusRight-handed childrenMiddle temporal gyrusSuperior temporal gyrusLanguage fMRI studyTemporal sulcusLateralized activationFMRI studyAngular gyrusLanguage organizationIndividual subject dataLanguage processingTemporal regionsBrain regionsControl conditionFrontal lobeAge 5GyrusSignificant activationFMRIDevelopmental aspects of language processing: fMRI of verbal fluency in children and adults
Gaillard WD, Sachs BC, Whitnah JR, Ahmad Z, Balsamo LM, Petrella JR, Braniecki SH, McKinney CM, Hunter K, Xu B, Grandin CB. Developmental aspects of language processing: fMRI of verbal fluency in children and adults. Human Brain Mapping 2003, 18: 176-185. PMID: 12599275, PMCID: PMC6871939, DOI: 10.1002/hbm.10091.Peer-Reviewed Original ResearchConceptsLaterality of activationSemantic verbal fluencyVerbal fluencyFluency taskFrontal gyrusSemantic verbal fluency taskInferior frontal gyrusSemantic fluency taskVerbal fluency taskMiddle frontal gyrusTask testingDevelopmental differencesLanguage processingFluencyBrain areasDevelopmental aspectsAge 7 yearsFMRIInterest approachBOLD fMRISPM 99GyrusActivation mapsChildrenAdultsfMRI identifies regional specialization of neural networks for reading in young children
Gaillard WD, Balsamo LM, Ibrahim Z, Sachs BC, Xu B. fMRI identifies regional specialization of neural networks for reading in young children. Neurology 2003, 60: 94-100. PMID: 12525725, DOI: 10.1212/wnl.60.1.94.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusFrontal gyrusTemporal-occipital junctionMiddle temporal gyrusYoung childrenSupplementary motor areaFusiform gyrusLanguage networkTemporal gyrusOccipital junctionLanguage lateralizationNative EnglishEarly readersWernicke's areaNeural networkMotor areaBrain regionsCognitive networksAge 6Prominent activationGyrusFMRIChildren 7Interest approachBOLD technique
2002
Neuroimaging Reveals Automatic Speech Coding during Perception of Written Word Meaning
Xu B, Grafman J, Gaillard WD, Spanaki M, Ishii K, Balsamo L, Makale M, Theodore WH. Neuroimaging Reveals Automatic Speech Coding during Perception of Written Word Meaning. NeuroImage 2002, 17: 859-870. PMID: 12377160, DOI: 10.1006/nimg.2002.1215.Peer-Reviewed Original ResearchConceptsSemantic processingWord meaningsVisual word perceptionMultiple cognitive tasksMechanisms of readingButton-press responseFunctional magnetic resonance imaging (fMRI) techniquesBehavioral response measuresSignificant bilateral activationPhonological recodingPhonological tasksWord perceptionWord readingLetter stringsCognitive tasksSemantic tasksNeural basisNeuroimaging sessionSpeech soundsBaseline taskPhonological processesNeural responsesVisual stimuliActive processingSpeech codeLanguage dominance in partial epilepsy patients identified with an fMRI reading task
Gaillard WD, Balsamo L, Xu B, Grandin CB, Braniecki SH, Papero PH, Weinstein S, Conry J, Pearl PL, Sachs B, Sato S, Jabbari B, Vezina LG, Frattali C, Theodore WH. Language dominance in partial epilepsy patients identified with an fMRI reading task. Neurology 2002, 59: 256-265. PMID: 12136067, DOI: 10.1212/wnl.59.2.256.Peer-Reviewed Original ResearchConceptsIntracarotid amobarbital testROI analysisRegional asymmetry indexTemporal lobe epilepsyPartial epilepsy patientsAsymmetry indexLanguage areasTemporal language areaQuantitative ROI analysisFrontal language areasMost patientsLanguage dominanceLobe epilepsyPartial epilepsyAmobarbital testEpilepsy patientsPatientsLanguage lateralizationTemporal areaQuantitative regionInterest analysisInterrater agreementEpilepsyVisual controlFMRIA Functional Magnetic Resonance Imaging Study of Left Hemisphere Language Dominance in Children
Balsamo LM, Xu B, Grandin CB, Petrella JR, Braniecki SH, Elliott TK, Gaillard WD. A Functional Magnetic Resonance Imaging Study of Left Hemisphere Language Dominance in Children. JAMA Neurology 2002, 59: 1168-1174. PMID: 12117366, DOI: 10.1001/archneur.59.7.1168.Peer-Reviewed Original ResearchConceptsFrontal gyrusTemporal gyrusLanguage dominanceFunctional magnetic resonance imaging studyLeft hemisphere language dominanceFunctional magnetic resonance imagingAuditory language taskStrong left lateralizationLeft inferior temporal gyrusInferior frontal gyrusFunctional magnetic resonanceMiddle temporal gyrusMiddle frontal gyrusHemisphere language dominanceInferior temporal gyrusMagnetic resonance imaging studyResonance imaging studyReceptive languageHemisphere lateralizationLeft lateralizationAreas of activationLanguage tasksLeft fusiformGreater activationHemispheric lateralization