2017
Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial
Zheng DJ, Lu X, Schore RJ, Balsamo L, Devidas M, Winick NJ, Raetz EA, Loh ML, Carroll WL, Sung L, Hunger SP, Angiolillo AL, Kadan‐Lottick N. Longitudinal analysis of quality‐of‐life outcomes in children during treatment for acute lymphoblastic leukemia: A report from the Children's Oncology Group AALL0932 trial. Cancer 2017, 124: 571-579. PMID: 29112230, PMCID: PMC5808870, DOI: 10.1002/cncr.31085.Peer-Reviewed Original ResearchMeSH KeywordsAffective SymptomsChildChild, PreschoolFemaleHumansLongitudinal StudiesMalePrecursor Cell Lymphoblastic Leukemia-LymphomaQuality of LifeSex CharacteristicsConceptsAverage-risk acute lymphoblastic leukemiaQuality of lifeEmotional impairmentsLife Inventory (PedsQL) Generic CoreHigh-risk patientsProspective cohort studyTime of diagnosisEnd of therapyAcute lymphoblastic leukemiaFamily-based interventionsCohort studyQoL impairmentMean ageLymphoblastic leukemiaQOL outcomesPediatric QualityProportion of individualsEarly screeningPopulation normsImpaired rangeImpairmentMonthsTime pointsFunctioning impairmentImpairment patternsThe Behavior Rating Inventory of Executive Function (BRIEF) to Identify Pediatric Acute Lymphoblastic Leukemia (ALL) Survivors At Risk for Neurocognitive Impairment
Viola A, Balsamo L, Neglia JP, Brouwers P, Ma X, Kadan-Lottick NS. The Behavior Rating Inventory of Executive Function (BRIEF) to Identify Pediatric Acute Lymphoblastic Leukemia (ALL) Survivors At Risk for Neurocognitive Impairment. Journal Of Pediatric Hematology/Oncology 2017, 39: 174-178. PMID: 28085741, PMCID: PMC5364064, DOI: 10.1097/mph.0000000000000761.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityChildCross-Sectional StudiesExecutive FunctionHumansLogistic ModelsNeurocognitive DisordersParentsPrecursor Cell Lymphoblastic Leukemia-LymphomaSurveys and QuestionnairesSurvivorsConceptsLeukemia survivorsNeurocognitive impairmentAttention-deficit/hyperactivity disorder (ADHD) outcomesPediatric acute lymphoblastic leukemia survivorsPediatric acute lymphoblastic leukemia treatmentAcute lymphoblastic leukemia survivorsAcute lymphoblastic leukemia treatmentPotential late effectsAcute lymphoblastic leukemiaMultivariate logistic regressionExecutive Function Parent FormCross-sectional studyOngoing clinical careBehavior Rating InventoryComprehensive neuropsychological assessmentElevated scoresFirst remissionClinical outcomesLymphoblastic leukemiaLate effectsClinical careRating InventoryLeukemia treatmentCognitive impairmentIndex score
2016
Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study
Kunin-Batson AS, Lu X, Balsamo L, Graber K, Devidas M, Hunger SP, Carroll WL, Winick NJ, Mattano LA, Maloney KW, Kadan-Lottick NS. Prevalence and predictors of anxiety and depression after completion of chemotherapy for childhood acute lymphoblastic leukemia: A prospective longitudinal study. Cancer 2016, 122: 1608-1617. PMID: 27028090, PMCID: PMC4860039, DOI: 10.1002/cncr.29946.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsAnxietyChildChild, PreschoolDepressionFamily RelationsFemaleHumansLongitudinal StudiesMalePrecursor Cell Lymphoblastic Leukemia-LymphomaPrevalenceProspective StudiesRandomized Controlled Trials as TopicConceptsAcute lymphoblastic leukemiaCompletion of treatmentGreater riskEmotional-behavioral functioningChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaAdjusted longitudinal analysesCompletion of chemotherapyDepressive symptoms 6 monthsSymptoms 6 monthsEmotional distressElevated anxiety scoresAnxiety 1 monthStandardized rating scalesElevated depression scoresChildren's emotional-behavioral functioningLymphoblastic leukemiaPredictors of anxietySocial support copingMeasures of copingDepressive symptomsGeneral populationDepression scoresPsychosocial interventionsEarly screening
2015
The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia
Balsamo LM, Sint KJ, Neglia JP, Brouwers P, Kadan-Lottick NS. The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia. Journal Of Pediatric Psychology 2015, 41: 319-328. PMID: 26514641, PMCID: PMC4852216, DOI: 10.1093/jpepsy/jsv103.Peer-Reviewed Original ResearchMeSH KeywordsAchievementAdolescentChildCross-Sectional StudiesFemaleHumansIntelligenceMaleMathematicsMotor SkillsPrecursor Cell Lymphoblastic Leukemia-LymphomaReadingSurvivorsConceptsFine motorLeukemia survivorsPediatric acute lymphoblastic leukemia survivorsAcute lymphoblastic leukemia survivorsAcute lymphoblastic leukemiaCross-sectional studyVisual-motor integration skillsFirst remissionPediatric survivorsLymphoblastic leukemiaEffect modificationSurvivorsMotor skillsFM skillsAssociationLow intelligenceRemissionLeukemiaIntegration skillsYearsProspective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331
Mitchell H, Lu X, Myers RM, Sung L, Balsamo LM, Carroll WL, Raetz E, Loh ML, Mattano LA, Winick NJ, Devidas M, Hunger SP, Maloney K, Kadan-Lottick N. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331. International Journal Of Cancer 2015, 138: 332-339. PMID: 26235006, PMCID: PMC5138856, DOI: 10.1002/ijc.29708.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolFemaleHumansLongitudinal StudiesMalePrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesQuality of LifeSurveys and QuestionnairesConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLife Inventory 4.0 Generic Core ScalesChildren's Oncology Group studyHRQoL 1 monthMean PedsQL scoresYears of therapyHealth-related qualityEnd of inductionHigh cure ratesGeneric Core ScalesSocial functioningRepeated-measures analysisTherapy completionTherapeutic trialsCure ratePediatric QualityPedsQL scoresConsiderable impairmentLongitudinal assessmentDiagnosisTherapyMonthsGroup studyChemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis
Iyer NS, Balsamo LM, Bracken MB, Kadan-Lottick NS. Chemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis. Blood 2015, 126: 346-353. PMID: 26048910, DOI: 10.1182/blood-2015-02-627414.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsBrain NeoplasmsChildCognition DisordersHumansPrecursor Cell Lymphoblastic Leukemia-LymphomaSurvival RateSurvivorsConceptsLong-term neurocognitive functioningAcute lymphoblastic leukemiaCranial radiationNeurocognitive functioningIntelligence quotientChildhood acute lymphoblastic leukemiaContinuous first remissionSurvivors of childhoodDatabase of AbstractsConfidence intervalsHealthy control groupStandard deviation scoreFine motor domainNeurocognitive domainsReviews of EffectsMEDLINE/PubMedFirst remissionFull-scale intelligence quotientPerformance intelligence quotientLymphoblastic leukemiaInformation processing speedDeviation scoreSD scoreModerate impairmentMultiple neurocognitive domains
2014
Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report
Lau S, Lu X, Balsamo L, Devidas M, Winick N, Hunger SP, Carroll W, Stork L, Maloney K, Kadan‐Lottick N. Family life events in the first year of acute lymphoblastic leukemia therapy: A children's oncology group report. Pediatric Blood & Cancer 2014, 61: 2277-2284. PMID: 25175168, PMCID: PMC4282930, DOI: 10.1002/pbc.25195.Peer-Reviewed Original ResearchMeSH KeywordsChildChild, PreschoolFamily RelationsFemaleFollow-Up StudiesHumansIncomeInfantLife Change EventsLongitudinal StudiesMaleMarriageParentsPrecursor Cell Lymphoblastic Leukemia-LymphomaPrognosisProspective StudiesStress, PsychologicalConceptsAcute lymphoblastic leukemiaChildren's Oncology Group reportChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemia therapyMonths of therapyProspective cohort studyAppropriate anticipatory guidanceHigh cure ratesLong-term outcomesMore childrenHealth care providersLess maternal educationFirst yearCohort studyPatient factorsCure rateLymphoblastic leukemiaCOG protocolsCare providersAnticipatory guidanceEligibility criteriaHigh incidenceLeukemia therapyMaternal educationAverage riskA prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia
Myers RM, Balsamo L, Lu X, Devidas M, Hunger SP, Carroll WL, Winick NJ, Maloney KW, Kadan‐Lottick N. A prospective study of anxiety, depression, and behavioral changes in the first year after a diagnosis of childhood acute lymphoblastic leukemia. Cancer 2014, 120: 1417-1425. PMID: 24473774, PMCID: PMC4319360, DOI: 10.1002/cncr.28578.Peer-Reviewed Original ResearchMeSH KeywordsAggressionAntineoplastic Combined Chemotherapy ProtocolsAnxietyAsparaginaseBehaviorChildChild, PreschoolCohort StudiesCyclophosphamideDepressionDexamethasoneEmotionsFemaleHumansLongitudinal StudiesMalePolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaProspective StudiesPsychomotor AgitationVincristineConceptsStandard-risk acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaUnhealthy family functioningHispanic ethnicityChildren's Oncology Group protocolsChildhood acute lymphoblastic leukemiaClinical rangeSubpopulation of patientsWorse physical functioningMore childrenFirst yearCoping Health InventoryCohort studyProspective studyRisk factorsPhysical functioningFamily functioningHealth InventoryFamily Assessment DevicePopulation normsMonthsFunctioning ScaleDepressionGroup protocol