1997
A cross sectional assessment of health status instruments in patients with rheumatoid arthritis participating in a clinical trial. Minocycline in Rheumatoid Arthritis Trial Group.
Tuttleman M, Pillemer S, Tilley B, Fowler S, Buckley L, Alarcón G, Trentham D, Neuner R, Clegg D, Leisen J, Heyse S. A cross sectional assessment of health status instruments in patients with rheumatoid arthritis participating in a clinical trial. Minocycline in Rheumatoid Arthritis Trial Group. The Journal Of Rheumatology 1997, 24: 1910-5. PMID: 9330931.Peer-Reviewed Original ResearchConceptsPatient global assessmentSF-36Rheumatoid arthritisM-HAQOutcome measuresClinical trialsGlobal assessmentShort Form Health SurveyFunctional health status measuresJoint swelling scoreRA clinical trialsRA outcome measuresHealth Assessment QuestionnaireHealth status instrumentsSF-36 scalesRheumatoid arthritis trialsHealth status measuresMultitrait scaling analysisCross-sectional assessmentCross-sectional analysisMIRA trialStudy patientsRA populationScore correlationsPain itemsEffects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis.
Buckley L, Leib E, Cartularo K, Vacek P, Cooper S. Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. The Journal Of Rheumatology 1997, 24: 1489-94. PMID: 9263140.Peer-Reviewed Original ResearchConceptsBone mineral densityLow-dose methotrexateRheumatoid arthritisLumbar spineFemoral neckDose methotrexateMineral densityBMD of patientsFemoral neck bone mineral densityNeck bone mineral densitySpine bone mineral densityMeasurement of BMDAntirheumatic drug useVitamin D3 supplementationYears of followupGreater bone lossDMARD useD3 supplementationFollowup visitMTX useBone lossPrednisoneSimilar dosePatientsMethotrexateRadiographic results from the Minocycline in Rheumatoid Arthritis (MIRA) Trial.
Bluhm G, Sharp J, Tilley B, Alarcon G, Cooper S, Pillemer S, Clegg D, Heyse S, Trentham D, Neuner R, Kaplan D, Leisen J, Buckley L, Duncan H, Tuttleman M, Li S, Fowler S. Radiographic results from the Minocycline in Rheumatoid Arthritis (MIRA) Trial. The Journal Of Rheumatology 1997, 24: 1295-302. PMID: 9228128.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnti-Bacterial AgentsArthritis, RheumatoidArthroscopyFemaleHumansMaleMiddle AgedMinocyclinePlacebosRadiographyTreatment OutcomeConceptsJoint space narrowingRheumatoid arthritis trialsDisease progressionArthritis trialsSpace narrowingPercentage of patientsSignificant differencesReported clinical resultsErosive jointsOral minocyclinePlacebo groupErosive diseaseFinal visitRadiographic progressionPlacebo treatmentTreat analysisRadiographic resultsFuture trialsClinical centersClinical resultsPosteroanterior filmsRadiographic changesTreatment benefitProgression rateWeek trial
1996
Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. A randomized, double-blind, placebo-controlled trial.
Buckley L, Leib E, Cartularo K, Vacek P, Cooper S. Calcium and vitamin D3 supplementation prevents bone loss in the spine secondary to low-dose corticosteroids in patients with rheumatoid arthritis. A randomized, double-blind, placebo-controlled trial. Annals Of Internal Medicine 1996, 125: 961-8. PMID: 8967706, DOI: 10.7326/0003-4819-125-12-199612150-00004.Peer-Reviewed Original ResearchConceptsBone mineral densityLow-dose corticosteroidsPlacebo-controlled trialVitamin D3 supplementationMineral densityRheumatoid arthritisVitamin D3Prednisone therapyLumbar spineD3 supplementationBone lossOutpatient care facilitiesLong-term useCorticosteroid useVertebral fracturesWard's triangleAutoimmune diseasesFemoral neckCorticosteroidsHigh riskSupplemental calciumRational therapyPatientsArthritisTherapy
1995
Effects of low dose corticosteroids on the bone mineral density of patients with rheumatoid arthritis.
Buckley L, Leib E, Cartularo K, Vacek P, Cooper S. Effects of low dose corticosteroids on the bone mineral density of patients with rheumatoid arthritis. The Journal Of Rheumatology 1995, 22: 1055-9. PMID: 7674230.Peer-Reviewed Original ResearchConceptsBone mineral densityRheumatoid arthritisLumbar spineFemoral neckMineral densityLow dosesLow-dose corticosteroid useLow bone mineral densitySimilar bone mineral densityLow-dose corticosteroidsMean daily doseEffect of corticosteroidsCross-sectional studyDose corticosteroidsPrednisone doseCorticosteroid useDisease durationDaily doseDaily dosesSectional studyRisk factorsStudy groupPatientsDisease severityCorticosteroidsMinocycline in rheumatoid arthritis. A 48-week, double-blind, placebo-controlled trial. MIRA Trial Group.
Tilley B, Alarcón G, Heyse S, Trentham D, Neuner R, Kaplan D, Clegg D, Leisen J, Buckley L, Cooper S, Duncan H, Pillemer S, Tuttleman M, Fowler S. Minocycline in rheumatoid arthritis. A 48-week, double-blind, placebo-controlled trial. MIRA Trial Group. Annals Of Internal Medicine 1995, 122: 81-9. PMID: 7993000, DOI: 10.7326/0003-4819-122-2-199501150-00001.Peer-Reviewed Original ResearchConceptsIgM rheumatoid factor levelsErythrocyte sedimentation rateRheumatoid factor levelsRheumatoid arthritisMinocycline groupGlobal assessmentPlacebo groupMore patientsPlatelet countModified Health Assessment QuestionnaireFactor levelsEfficacy of minocyclineEvaluator's global assessmentWeek 48 visitActive rheumatoid arthritisHealth Assessment QuestionnairePatient global assessmentPlacebo-controlled trialModerate rheumatoid arthritisDisease-modifying drugsMechanism of actionJoint tendernessMorning stiffnessStudy medicationDisease activity
1990
Administration of folinic acid after low dose methotrexate in patients with rheumatoid arthritis.
Buckley L, Vacek P, Cooper S. Administration of folinic acid after low dose methotrexate in patients with rheumatoid arthritis. The Journal Of Rheumatology 1990, 17: 1158-61. PMID: 2132565.Peer-Reviewed Original ResearchConceptsLow-dose methotrexateFolinic acidDose methotrexateRheumatoid arthritisShort-term side effectsDose of methotrexateIncidence of stomatitisFolinic acid supplementationTerm side effectsLeucovorin treatmentAntiarthritic effectsGastrointestinal toxicityMTX administrationCrossover trialTherapeutic effectAcid supplementationSide effectsMethotrexateLeucovorinArthritisSignificant differencesPatientsAdministrationDosePlaceboEducational and psychosocial needs of patients with chronic disease: A survey of preferences of patients with rheumatoid arthritis
Buckley L, Vacek P, Cooper S. Educational and psychosocial needs of patients with chronic disease: A survey of preferences of patients with rheumatoid arthritis. Arthritis & Rheumatism 1990, 3: 5-10. PMID: 2285739, DOI: 10.1002/art.1790030103.Peer-Reviewed Original Research