1997
Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis.
Buckley L, Leib E, Cartularo K, Vacek P, Cooper S. Effects of low dose methotrexate on the bone mineral density of patients with rheumatoid arthritis. The Journal Of Rheumatology 1997, 24: 1489-94. PMID: 9263140.Peer-Reviewed Original ResearchConceptsBone mineral densityLow-dose methotrexateRheumatoid arthritisLumbar spineFemoral neckDose methotrexateMineral densityBMD of patientsFemoral neck bone mineral densityNeck bone mineral densitySpine bone mineral densityMeasurement of BMDAntirheumatic drug useVitamin D3 supplementationYears of followupGreater bone lossDMARD useD3 supplementationFollowup visitMTX useBone lossPrednisoneSimilar dosePatientsMethotrexate
1990
Administration of folinic acid after low dose methotrexate in patients with rheumatoid arthritis.
Buckley L, Vacek P, Cooper S. Administration of folinic acid after low dose methotrexate in patients with rheumatoid arthritis. The Journal Of Rheumatology 1990, 17: 1158-61. PMID: 2132565.Peer-Reviewed Original ResearchConceptsLow-dose methotrexateFolinic acidDose methotrexateRheumatoid arthritisShort-term side effectsDose of methotrexateIncidence of stomatitisFolinic acid supplementationTerm side effectsLeucovorin treatmentAntiarthritic effectsGastrointestinal toxicityMTX administrationCrossover trialTherapeutic effectAcid supplementationSide effectsMethotrexateLeucovorinArthritisSignificant differencesPatientsAdministrationDosePlacebo