Featured Publications
Inaccuracy of pulse oximetry with dark skin pigmentation: clinical implications and need for improvement
Kyriacou PA, Charlton PH, Al-Halawani R, Shelley KH. Inaccuracy of pulse oximetry with dark skin pigmentation: clinical implications and need for improvement. British Journal Of Anaesthesia 2022, 130: e33-e36. PMID: 35430087, DOI: 10.1016/j.bja.2022.03.011.Peer-Reviewed Original ResearchCOVID-19: Pulse oximeters in the spotlight
Michard F, Shelley K, L’Her E. COVID-19: Pulse oximeters in the spotlight. Journal Of Clinical Monitoring And Computing 2020, 35: 11-14. PMID: 32578070, PMCID: PMC7308445, DOI: 10.1007/s10877-020-00550-7.Peer-Reviewed Original ResearchConceptsPeripheral perfusion indexAcute respiratory failureManagement of patientsIntensive care unitCoronavirus disease 2019Preload-modifying maneuverPulse oximetry waveformRespiratory failureCare unitFluid therapyPreload responsivenessPerfusion indexRespiratory effortDisease 2019Oxygen saturationPulse oximetryHospital wardsPulse oximeterSpO2PatientsTherapyOximetryWards
2016
Ventilation-Induced Modulation of Pulse Oximeter Waveforms
Alian AA, Atteya G, Gaal D, Golembeski T, Smith BG, Dai F, Silverman DG, Shelley K. Ventilation-Induced Modulation of Pulse Oximeter Waveforms. Anesthesia & Analgesia 2016, 123: 346-356. PMID: 27284998, DOI: 10.1213/ane.0000000000001377.Peer-Reviewed Original ResearchConceptsSystolic blood pressureArterial pressure waveformBlood volumeFluid resuscitationBlood pressureOnly systolic blood pressurePressure waveformAirway pressure waveformFinger pulse oximetrySubstantial blood lossDynamic preload indicesVenous blood volumeArterial pressure measurementsArterial waveform parametersP-valuePulse oximeter waveformWilcoxon signed-rank testArterial pressureBlood lossBlood transfusionEarly bleedingPediatric patientsPreload indexHemodynamic dataScoliosis surgery
2013
Is pulse oximetry an essential tool or just another distraction? The role of the pulse oximeter in modern anesthesia care
Shah A, Shelley KH. Is pulse oximetry an essential tool or just another distraction? The role of the pulse oximeter in modern anesthesia care. Journal Of Clinical Monitoring And Computing 2013, 27: 235-242. PMID: 23314807, DOI: 10.1007/s10877-013-9428-7.Peer-Reviewed Original ResearchConceptsPulse oximetryOutcome studiesAnesthesia carePulse oximeterStandard of careAnesthetic agentsClinical careClinical monitoringPatient careFirst operationCardiovascular monitoringOximetryAvailable evidenceAnesthesiologistsCareOutcomes researchAmerican SocietyFurther studiesPatientsOximeterPatient monitoringRare eventUnambiguous roleNoninvasive cardiovascular monitoringVast majority
2012
Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion?
Phillips J, Belhaj A, Shafqat K, Langford R, Shelley K, Kyriacou P. Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion? Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2012, 2012: 3644-3647. PMID: 23366717, DOI: 10.1109/embc.2012.6346756.Peer-Reviewed Original ResearchConceptsVenous oxygen saturationOxygen saturationBlood volumeNegative airway pressureAirway pressureVenous bloodArterial saturationRespiratory modulationHealthy volunteersRespiratory frequencyTissue bedsPilot studyResultant modulationArteryModulationFingerBloodPhotoplethysmographic signalsVolunteersRespiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform
Alian AA, Shelley KH. Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform. Sensors 2012, 12: 2236-2254. PMID: 22438762, PMCID: PMC3304164, DOI: 10.3390/s120202236.Peer-Reviewed Original Research
2010
Measuring venous oxygenation using the photoplethysmograph waveform
Walton ZD, Kyriacou PA, Silverman DG, Shelley KH. Measuring venous oxygenation using the photoplethysmograph waveform. Journal Of Clinical Monitoring And Computing 2010, 24: 295-303. PMID: 20644985, DOI: 10.1007/s10877-010-9248-y.Peer-Reviewed Original ResearchConceptsVenous saturationVenous systemRegional venous oxygen saturationPeripheral venous waveformCardiac surgery patientsVenous oxygen saturationPeripheral venous systemPhotoplethysmograph waveformsWilcoxon signed-rank testVenous waveformSurgery patientsAtrial contractionSigned-rank testVenous bloodVenous oxygenationOxygen saturationGold standardPPG characteristicsHigh complianceBonferroni correctionSignificant differencesPPG analysisBloodPPG waveformPatients
2007
Photoplethysmography: Beyond the Calculation of Arterial Oxygen Saturation and Heart Rate
Shelley KH. Photoplethysmography: Beyond the Calculation of Arterial Oxygen Saturation and Heart Rate. Anesthesia & Analgesia 2007, 105: s31-s36. PMID: 18048895, DOI: 10.1213/01.ane.0000269512.82836.c9.Peer-Reviewed Original Research