2018
Predictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB)
Miccio J, Jairam V, Gao S, Augustyn A, Oladeru O, Onderdonk B, Costa J, Han D, Khan S, Friedlaender G, Lindskog D, Deshpande H, Tara H, Osborn H, Roberts K, Patel K. Predictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB). International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e335. DOI: 10.1016/j.ijrobp.2018.07.1028.Peer-Reviewed Original Research
1988
Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging.
Leyvraz S, Costa J. Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging. Die Orthopädie 1988, 17: 121-7. PMID: 3290794.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasTissue sarcomasDifferent prognostic factorsManagement of patientsStratification of patientsPrognostic factorsSimilar prognosisSurgical marginsHistological diagnosisStaging systemClinical aspectsOptimal diagnosisTumorsPatientsDiagnosisPrognosisSarcomaStagingCliniciansPathologistsGrading
1986
High‐grade soft tissue sarcomas of the extremities
Potter D, Kinsella T, Glatstein E, Wesley R, White D, Seipp C, Chang A, Lack E, Costa J, Rosenberg S. High‐grade soft tissue sarcomas of the extremities. Cancer 1986, 58: 190-205. PMID: 3518911, DOI: 10.1002/1097-0142(19860701)58:1<190::aid-cncr2820580133>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdolescentAdultAgedAmputation, SurgicalAntineoplastic Combined Chemotherapy ProtocolsArmChildClinical Trials as TopicCombined Modality TherapyFemaleFollow-Up StudiesHumansLegMaleMiddle AgedNeoplasm MetastasisNeoplasm Recurrence, LocalPrognosisRandom AllocationSarcomaThighConceptsHigh-grade soft tissue sarcomasSoft tissue sarcomasNational Cancer InstituteLimb-sparing proceduresSignificant prognostic variablesOverall survivalAdjuvant chemotherapyTissue sarcomasPrognostic variablesDecreased overall survivalOutcomes of patientsDisease-free survivalMicroscopic marginsPostoperative radiotherapyFirst recurrenceProspective trialRecurrent diseaseSurgery BranchHistologic typeLocal excisionRandomized trialsPatient refusalTumor sizeCancer InstitutePatients
1985
A randomized, prospective trial of adjuvant chemotherapy in adults with soft tissue sarcomas of the head and neck, breast, and trunk
Glenn J, Kinsella T, Glatstein E, Tepper J, Baker A, Sugarbaker P, Sindelar W, Roth J, Brennan M, Costa J, Seipp C, Wesley R, Young R, Rosenberg S. A randomized, prospective trial of adjuvant chemotherapy in adults with soft tissue sarcomas of the head and neck, breast, and trunk. Cancer 1985, 55: 1206-1214. PMID: 3882217, DOI: 10.1002/1097-0142(19850315)55:6<1206::aid-cncr2820550612>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsDisease-free survivalActuarial disease-free survivalOverall actuarial survivalChemotherapy armAdjuvant chemotherapyOverall survivalActuarial survivalApparent congestive heart failureAggressive local treatmentUse of chemotherapyCongestive heart failureSubgroup of patientsHigh-grade sarcomaSoft tissue sarcomasPostoperative radiotherapyProspective trialComplete resectionHeart failureAdditional patientsTreatment armsGross tumorProspective studyTissue sarcomasLocal treatmentChemotherapy
1984
The grading of soft tissue sarcomas results of a clinicohistopathologic correlation in a series of 163 cases
Costa J, Wesley R, Glatstein E, Rosenberg S. The grading of soft tissue sarcomas results of a clinicohistopathologic correlation in a series of 163 cases. Cancer 1984, 53: 530-541. PMID: 6692258, DOI: 10.1002/1097-0142(19840201)53:3<530::aid-cncr2820530327>3.0.co;2-d.Peer-Reviewed Original ResearchConceptsPrimary lesionOverall survivalAggressive lesionsPatient survivalBetter patient survivalSoft tissue sarcomasMinimal metastatic potentialPoor patient survivalGroup of lesionsUse of necrosisFirst recurrenceClinical courseHistologic typingHistologic featuresTissue sarcomasHistopathologic parametersStratified analysisHistologic parametersLesionsClinicohistopathologic correlationMetastatic potentialGrading systemPatientsRecurrenceNecrosis
1983
Prospective randomized evaluation of adjuvant chemotherapy in adults with soft tissue sarcomas of the extremities
Rosenberg S, Tepper J, Glatstein E, Costa J, Young R, Baker A, Brennan M, Demoss E, Seipp C, Sindelar W, Sugarbaker P, Wesley R. Prospective randomized evaluation of adjuvant chemotherapy in adults with soft tissue sarcomas of the extremities. Cancer 1983, 52: 424-434. PMID: 6344981, DOI: 10.1002/1097-0142(19830801)52:3<424::aid-cncr2820520307>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasDisease-free survivalAdjuvant chemotherapyChemotherapy groupOverall survivalTissue sarcomasPilot trialPatient groupRadiation therapyHigh-grade soft tissue sarcomasContinuous disease-free survivalLocal failureHigh-dose methotrexatePercent of patientsLimb-sparing surgeryImmediate postoperative periodProspective Randomized EvaluationWide local resectionPrevious pilot trialUnderwent amputationAdult patientsLocal resectionPostoperative periodLocal therapyActuarial analysis
1982
The Treatment of Soft-tissue Sarcomas of the Extremities
ROSENBERG S, TEPPER J, GLATSTEIN E, COSTA J, BAKER A, BRENNAM M, DEMOSS E, SEIPP C, SINDELAR W, SUGARBAKER P, WESLEY R. The Treatment of Soft-tissue Sarcomas of the Extremities. Annals Of Surgery 1982, 196: 305-315. PMID: 7114936, PMCID: PMC1352604, DOI: 10.1097/00000658-198209000-00009.Peer-Reviewed Original ResearchConceptsSoft tissue sarcomasHigh-grade soft tissue sarcomasLimb-sparing groupLimb-sparing resectionLocal recurrencePostoperative chemotherapyAdult patientsTissue sarcomasRadiation therapySurvival rateDisease-free survival ratesAdjuvant radiation therapyHigh-dose methotrexateLimb-sparing surgeryOverall survival rateProspective Randomized StudyWide local excisionJoint proximalAdjuvant chemotherapyResection groupPostoperative radiotherapyOverall survivalRandomized studyLocal excisionAmputation group
1981
Adjuvant Chemotherapy for Patients with Soft Tissue Sarcomas
Rosenberg S, Tepper J, Glatstein E, Costa J, Young R, Seipp C, Wesley R. Adjuvant Chemotherapy for Patients with Soft Tissue Sarcomas. Surgical Clinics Of North America 1981, 61: 1415-1423. PMID: 7031940, DOI: 10.1016/s0039-6109(16)42595-8.Peer-Reviewed Original Research